12 research outputs found
PET and MRI based treatment planning systems: a methodology for realistic evaluation of the dose and fluence distribution in BNCT and in GdNCT
An overview on the developments and improvements of a new treatment planning system for BNCT
PET and MRI based treatment planning systems: a methodology for a realistic evaluation of the dose and fluence distributions in BNCT and in GdNCT
Spectrum shaping assessment of accelerator-based fusion neutron sources to be used in BNCT treatment
An overview on the developments and improvements of a treatment planning system for BNCT
Development of a treatment planning system for BNCT based on positron emission tomography data - preliminary results
Experimental and Computational Validation of BDTPS using a Heterogeneous Boron Phantom
none5DAQUINO G.G; N. CERULLO; MAZZINI M; MOSS R.L; MUZI LDAQUINO G., G; Cerullo, Nicola; Mazzini, M; MOSS R., L; Muzi, L
Gel dosimetry in the BNCT facility for extra-corporeal treatment of liver cancer at the HFR Petten
A thorough evaluation of the dose inside a specially designed and built facility for extra-corporeal treatment of liver cancer by boron neutron capture therapy (BNCT) at the High Flux Reactor (HFR) Petten (The Netherlands) is the necessary step before animal studies can start. The absorbed doses are measured by means of gel dosemeters, which help to validate the Monte Carlo simulations of the spheroidal liver holder that will contain the human liver for irradiation with an epithermal neutron beam. These dosemeters allow imaging of the dose due to gammas and to the charged particles produced by the 10B reaction. The thermal neutron flux is extrapolated from the boron dose images and compared to that obtained by the calculations. As an additional reference, Au, Cu and Mn foil measurements are performed. All results appear consistent with the calculations and confirm that the BNCT liver facility is able to provide an almost homogeneous thermal neutron distribution in the liver, which is a requirement for a successful treatment of liver metastases