OR and 95% CI of cardiopulmonary complications for PS vs. TS during gastrointestinal endoscopy in all of the patients.

<p>OR and 95% CI of cardiopulmonary complications for PS vs. TS during gastrointestinal endoscopy in all of the patients.</p

Funnel plot assessing publication bias.

<p>No publication bias was noted. SE, standard error.</p

Forest plot demonstrating amnesia with PS vs. TS for gastrointestinal endoscopy.

<p>Forest plot demonstrating amnesia with PS vs. TS for gastrointestinal endoscopy.</p

Forest plot demonstrating discharge time with PS vs. TS for gastrointestinal endoscopy.

<p>Forest plot demonstrating discharge time with PS vs. TS for gastrointestinal endoscopy.</p

PSCs derived Galectin-1 promotes the proliferative activity (S-phase fraction) of CFPAC-1 cells.

<p>(a–c) Quantitative graphical representation of Apoptosis, G1, G2 and S cell population. Points, average of three independent experiments. a, CFPAC-1; b, CFPAC-1 + hNPSC; c, CFPAC-1 + hCaPSC. (d) A bar-graphical representation S-Phase Fraction cells in each group. *<i>p</i><0.01 <i>vs</i>. CFPAC-1, #<i>p</i><0.05 <i>vs</i>. hNPSC+CFPAC-1, ^△<i>p</i>>0.05 <i>vs</i>. hNPSC +β-Lactose.</p

The Use of Propofol as a Sedative Agent in Gastrointestinal Endoscopy: A Meta-Analysis

<div><h3>Objectives</h3><p>To assess the efficacy and safety of propofol sedation for gastrointestinal endoscopy, we conducted a meta-analysis of randomized controlled trials (RCTs) comparing propofol with traditional sedative agents.</p> <h3>Methods</h3><p>RCTs comparing the effects of propofol and traditional sedative agents during gastrointestinal endoscopy were found on MEDLINE, the Cochrane Central Register of Controlled Trials, and EMBASE. Cardiopulmonary complications (i.e., hypoxia, hypotension, arrhythmia, and apnea) and sedation profiles were assessed.</p> <h3>Results</h3><p>Twenty-two original RCTs investigating a total of 1,798 patients, of whom 912 received propofol only and 886 received traditional sedative agents only, met the inclusion criteria. Propofol use was associated with shorter recovery (13 studies, 1,165 patients; WMD –19.75; 95% CI –27.65, 11.86) and discharge times (seven studies, 471 patients; WMD –29.48; 95% CI –44.13, –14.83), higher post-anesthesia recovery scores (four studies, 503 patients; WMD 2.03; 95% CI 1.59, 2.46), better sedation (nine studies, 592 patients; OR 4.78; 95% CI 2.56, 8.93), and greater patient cooperation (six studies, 709 patients; WMD 1.27; 95% CI 0.53, 2.02), as well as more local pain on injection (six studies, 547 patients; OR 10.19; 95% CI 3.93, 26.39). Effects of propofol on cardiopulmonary complications, procedure duration, amnesia, pain during endoscopy, and patient satisfaction were not found to be significantly different from those of traditional sedative agents.</p> <h3>Conclusions</h3><p>Propofol is safe and effective for gastrointestinal endoscopy procedures and is associated with shorter recovery and discharge periods, higher post-anesthesia recovery scores, better sedation, and greater patient cooperation than traditional sedation, without an increase in cardiopulmonary complications. Care should be taken when extrapolating our results to specific practice settings and high-risk patient subgroups.</p> </div

Galectin-1 intensity of staining and clinicopathologic characteristics of the 18 patients with chronic pancreatitis and 66 patients with pancreatic cancer.

<p>UICC, International Union Against Cancer; PNI, perineural invasion.</p

Additional file 1: of Galectin-1 from cancer-associated fibroblasts induces epithelial–mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancer

Supplementary Table. Association of Gal-1 and Gli1 with clinicopathological indicators: age and gender. (DOC 33 kb

Forest plot demonstrating patient cooperation with PS vs. TS for gastrointestinal endoscopy.

<p>Forest plot demonstrating patient cooperation with PS vs. TS for gastrointestinal endoscopy.</p

Forest plot demonstrating patient satisfaction with PS vs. TS for gastrointestinal endoscopy.

<p>Forest plot demonstrating patient satisfaction with PS vs. TS for gastrointestinal endoscopy.</p