4,754 research outputs found
The CP-violating asymmetry in \eta\to\pi^+ \pi^- e^+e^-
We study the CP-violating asymmetry {\cal A}_{\rm CP}, which arises, in
\eta\to\pi^+\pi^- e^+e^-, from the angular correlation of the e^+ e^- and
\pi^+\pi^- planes due to the interference between the magnetic and electric
decay amplitudes. With the phenomenologically determined magnetic amplitude and
branching ratio as input, the asymmetry, induced by the electric bremsstrahlung
amplitude through the CP-violating decay \eta\to\pi^+\pi^-, and by an
unconventional tensor type operator, has been estimated respectively. The upper
bound of {\cal A}_{\rm CP} from the former is about 10^{-3}, and the asymmetry
from the latter might be up to O(10^{-2}). One can therefore expect that this
CP asymmetry would be an interesting CP-violating observable for the future
precise measurements in the \eta factories.Comment: LaTeX, 6 pages. One reference corrected, and some new references
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Pair formation and collapse in imbalanced Fermion populations with unequal masses
We present an exact Quantum Monte Carlo study of the effect of unequal masses
on pair formation in Fermionic systems with population imbalance loaded into
optical lattices. We have considered three forms of the attractive interaction
and find in all cases that the system is unstable and collapses as the mass
difference increases and that the ground state becomes an inhomogeneous
collapsed state. We also address the question of canonical vs grand canonical
ensemble and its role, if any, in stabilizing certain phases
Smartphone-Delivered Ecological Momentary Interventions Based on Ecological Momentary Assessments to Promote Health Behaviors: Systematic Review and Adapted Checklist for Reporting Ecological Momentary Assessment and Intervention Studies.
BACKGROUND: Healthy behaviors are crucial for maintaining a person's health and well-being. The effects of health behavior interventions are mediated by individual and contextual factors that vary over time. Recently emerging smartphone-based ecological momentary interventions (EMIs) can use real-time user reports (ecological momentary assessments [EMAs]) to trigger appropriate support when needed in daily life. OBJECTIVE: This systematic review aims to assess the characteristics of smartphone-delivered EMIs using self-reported EMAs in relation to their effects on health behaviors, user engagement, and user perspectives. METHODS: We searched MEDLINE, Embase, PsycINFO, and CINAHL in June 2019 and updated the search in March 2020. We included experimental studies that incorporated EMIs based on EMAs delivered through smartphone apps to promote health behaviors in any health domain. Studies were independently screened. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed. We performed a narrative synthesis of intervention effects, user perspectives and engagement, and intervention design and characteristics. Quality appraisal was conducted for all included studies. RESULTS: We included 19 papers describing 17 unique studies and comprising 652 participants. Most studies were quasi-experimental (13/17, 76%), had small sample sizes, and great heterogeneity in intervention designs and measurements. EMIs were most popular in the mental health domain (8/17, 47%), followed by substance abuse (3/17, 18%), diet, weight loss, physical activity (4/17, 24%), and smoking (2/17, 12%). Of the 17 studies, the 4 (24%) included randomized controlled trials reported nonstatistically significant effects on health behaviors, and 4 (24%) quasi-experimental studies reported statistically significant pre-post improvements in self-reported primary outcomes, namely depressive (P<.001) and psychotic symptoms (P=.03), drinking frequency (P<.001), and eating patterns (P=.01). EMA was commonly used to capture subjective experiences as well as behaviors, whereas sensors were rarely used. Generally, users perceived EMIs to be helpful. Common suggestions for improvement included enhancing personalization, multimedia and interactive capabilities (eg, voice recording), and lowering the EMA reporting burden. EMI and EMA components were rarely reported and were not described in a standardized manner across studies, hampering progress in this field. A reporting checklist was developed to facilitate the interpretation and comparison of findings and enhance the transparency and replicability of future studies using EMAs and EMIs. CONCLUSIONS: The use of smartphone-delivered EMIs using self-reported EMAs to promote behavior change is an emerging area of research, with few studies evaluating efficacy. Such interventions could present an opportunity to enhance health but need further assessment in larger participant cohorts and well-designed evaluations following reporting checklists. Future research should explore combining self-reported EMAs of subjective experiences with objective data passively collected via sensors to promote personalization while minimizing user burden, as well as explore different EMA data collection methods (eg, chatbots). TRIAL REGISTRATION: PROSPERO CRD42019138739; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=138739
Control of non-controllable quantum systems: A quantum control algorithm based on Grover iteration
A new notion of controllability, eigenstate controllability, is defined for
finite-dimensional bilinear quantum mechanical systems which are neither
strongly completely controllably nor completely controllable. And a quantum
control algorithm based on Grover iteration is designed to perform a quantum
control task of steering a system, which is eigenstate controllable but may not
be (strongly) completely controllable, from an arbitrary state to a target
state.Comment: 7 pages, no figures, submitte
Interleukin-18 expression increases in response to neurovascular damage following soman-induced status epilepticus in rats
Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and cardiovascular diseases, may also negatively affect the brain and contribute to central nervous system diseases. Air pollution is comprised of ambient particulate matter (PM) of different sizes, gases, organic compounds, and metals. An important contributor to PM is represented by traffic-related air pollution, mostly ascribed to diesel exhaust (DE). Epidemiological and animal studies have shown that exposure to air pollution may be associated with multiple adverse effects on the central nervous system. In addition to a variety of behavioral abnormalities, the most prominent effects caused by air pollution are oxidative stress and neuro-inflammation, which are seen in both humans and animals, and are supported by in vitro studies. Among factors which can affect neurotoxic outcomes, age is considered most relevant. Human and animal studies suggest that air pollution may cause developmental neurotoxicity, and may contribute to the etiology of neurodevelopmental disorders, including autism spectrum disorder. In addition, air pollution exposure has been associated with increased expression of markers of neurodegenerative disease pathologies, such as alpha-synuclein or beta-amyloid, and may thus contribute to the etiopathogenesis of neurodegenerative diseases, particularly Alzheimer's disease and Parkinson's disease
Increased expression of the chemokines CXCL1 and MIP-1α by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status epilepticus in rats
<p>Abstract</p> <p>Background</p> <p>Exposure to the nerve agent soman (GD) causes neuronal cell death and impaired behavioral function dependent on the induction of status epilepticus (SE). Little is known about the maturation of this pathological process, though neuroinflammation and infiltration of neutrophils are prominent features. The purpose of this study is to quantify the regional and temporal progression of early chemotactic signals, describe the cellular expression of these factors and the relationship between expression and neutrophil infiltration in damaged brain using a rat GD seizure model.</p> <p>Methods</p> <p>Protein levels of 4 chemokines responsible for neutrophil infiltration and activation were quantified up to 72 hours in multiple brain regions (i.e. piriform cortex, hippocampus and thalamus) following SE onset using multiplex bead immunoassays. Chemokines with significantly increased protein levels were localized to resident brain cells (i.e. neurons, astrocytes, microglia and endothelial cells). Lastly, neutrophil infiltration into these brain regions was quantified and correlated to the expression of these chemokines.</p> <p>Results</p> <p>We observed significant concentration increases for CXCL1 and MIP-1α after seizure onset. CXCL1 expression originated from neurons and endothelial cells while MIP-1α was expressed by neurons and microglia. Lastly, the expression of these chemokines directly preceded and positively correlated with significant neutrophil infiltration in the brain. These data suggest that following GD-induced SE, a strong chemotactic response originating from various brain cells, recruits circulating neutrophils to the injured brain.</p> <p>Conclusions</p> <p>A strong induction of neutrophil attractant chemokines occurs following GD-induced SE resulting in neutrophil influx into injured brain tissues. This process may play a key role in the progressive secondary brain pathology observed in this model though further study is warranted.</p
User-Centered Event Data Modelling and Analytics
Conventional data analytics platforms are not adequate to be applied in the management of emergency situations. The 3V the usually characterize big data (volume, variety, velocity) along with the issue of integrating information coming from heterogeneous networks require the development of new systems. In this paper we provide the design of a data analytics platform that we are developing around the concept of event, that is simple or complex data stream gathered from physical and social sensors that are encapsulated with contextual information (space, time, thematics). Copyright \ua9 2014 for the individual papers by the papers' authors
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