Investigate the Structural Response of Ultra High Performance Concrete Column under the High Explosion

Most of the structures that are damaged by an explosion are not initially designed to resist this kind of load. In the overall structure of any building, columns play an important role to prevent the collapse of frame structure under blast impact. Hence, the main concept in the blast resistance design of the structure is to improve the blast load capacity of the column. In this study, dynamic analysis and numerical model of Ultra High Performance Concrete (UHPC) column under high explosive load, is presented. Based on the Johnson Holmquist 2 damage model and the subroutine in the ABAQUS platform, a total of twenty UHPC model of the column were calculated. The objective of the article is to investigate the structural response of the UHPC column and locate the most vulnerable scenarios to propose necessary recommendations for the UHPC column in the blast loading resistance design. The input parameters, including the effect of various shapes of cross-section, scaled distance, steel reinforcement ratio, and cross-section area, are analyzed to clarify the dynamic behavior of the UHPC column subjected to blast loading. Details of the numerical data, and the discussion on the important obtained results, are also provided in this paper

A Study on Design and Control of the Multi-Station Multi-Container Transportation System

In considering the problem of saving spaces during the transportation of items from one station to another, for example, in warehouses, factories, hospitals, etc., an automatic transportation system (ATS) that could take advantage of the above ceiling spaces for the transportation of products is considered. Such a system guarantees that the activities occurring in the floor area will be maintained as usual. To achieve this requirement, the ceiling spaces of a building are used to construct an automatic multi-station multi-container (MSMC) transportation system. This system can transport items from one place to another in the whole system. This system is designed to utilize the spaces above the ceiling, and it has the advantage of saving floor space for transportation operations. This will increase the operational capability of the industries and also improve the productivity of the industry in which this system is implemented. The entire transportation system includes (1) the essential conveying system (which is a functional conveyor module with a specified number of containers); (2) the control block that can monitor and operate the system; and (3) the sensor block for detecting and identifying the containers. The content of this article focuses on the introduction of the mechanical system (1); the control system (2); and the operating principle of the whole system (3)

A Study on Design and Control of the Multi-Station Multi-Container Transportation System

In considering the problem of saving spaces during the transportation of items from one station to another, for example, in warehouses, factories, hospitals, etc., an automatic transportation system (ATS) that could take advantage of the above ceiling spaces for the transportation of products is considered. Such a system guarantees that the activities occurring in the floor area will be maintained as usual. To achieve this requirement, the ceiling spaces of a building are used to construct an automatic multi-station multi-container (MSMC) transportation system. This system can transport items from one place to another in the whole system. This system is designed to utilize the spaces above the ceiling, and it has the advantage of saving floor space for transportation operations. This will increase the operational capability of the industries and also improve the productivity of the industry in which this system is implemented. The entire transportation system includes (1) the essential conveying system (which is a functional conveyor module with a specified number of containers); (2) the control block that can monitor and operate the system; and (3) the sensor block for detecting and identifying the containers. The content of this article focuses on the introduction of the mechanical system (1); the control system (2); and the operating principle of the whole system (3)

Effect of calophyllolide on myeloperoxidase (MPO) activity.

<p>All mice were sacrificed on day 1 and day 5 post-operation, and skin tissue samples were collected to assess MPO activity (n = 3 mice per group per experiment). Data are represented as mean ± SEM and compared by one-way ANOVA. *** P<0.001.</p

Anti-inflammatory and wound healing activities of calophyllolide isolated from <i>Calophyllum inophyllum</i> Linn

<div><p>Due to the high-cost and limitations of current wound healing treatments, the search for alternative approaches or drugs, particularly from medicinal plants, is of key importance. In this study, we report anti-inflammatory and wound healing activities of the major calophyllolide (CP) compound isolated from <i>Calophyllum inophyllum</i> Linn. The results showed that CP had no effect on HaCaT cell viability over a range of concentrations. CP reduced fibrosis formation and effectively promoted wound closure in mouse model without causing body weight loss. The underlying molecular mechanisms of wound repair by CP was investigated. CP markedly reduced MPO activity, and increased M2 macrophage skewing, as shown by up-regulation of M2-related gene expression, which is beneficial to the wound healing process. CP treatment prevented a prolonged inflammatory process by down-regulation of the pro-inflammatory cytokines—IL-1β, IL-6, TNF-α, but up-regulation of the anti-inflammatory cytokine, IL-10. This study is the first to indicate a plausible role for CP in accelerating the process of wound healing through anti-inflammatory activity mechanisms, namely, by regulation of inflammatory cytokines, reduction in MPO, and switching of macrophages to an M2 phenotype. These findings may enable the utilization of CP as a potent therapeutic for cutaneous wound healing.</p></div

Effect of calophyllolide (CP) on acceleration of wound closure.

<p>Effect of calophyllolide (CP) on acceleration of wound closure.</p

Attenuation of inflammatory cytokines expression by calophyllolide.

<p>Serum levels of (<b>A</b>) IL-1β, (<b>B</b>) IL-6, (<b>C</b>) TNF-α, and (<b>D</b>) IL-10. Data are represented as mean ± SEM and compared by one-way ANOVA (n = 3 mice per group per experiment). * P<0.05, ** P<0.01, *** P<0.001.</p

Histological and quantitative analyses of the cutaneous wound healing of calophyllolide.

<p>Mice were daily treated with CP (6 mg/animal) and PI (100 mg/animal) until enthanasia. <b>(A)</b> Histological observation of collagen on wound healing at day 14 by Masson’s Trichrome staining. Reduction of collagenous scar (arrow head) in CP-treated group compared to vehicle- and PI-treated groups. Arrows indicate wound site with scale bar = 1cm. <b>(B)</b> Representative graph of semi-quantitative collagen content at day 10 and day 14 (n = 3–4 animals per group per experiment). Data are represented as mean ± SEM and compared by one-way ANOVA.</p

Effect of calophyllolide on HaCaT and RAW264.7 cell viability.

<p>HPLC chromatograms of the isolated calophyollide <b>(A)</b> and standard control <b>(B)</b>. This compound was recorded at 233 nm, and its retention time is 36.6 min. <b>(C)</b> No effect of CP on the viability of both HaCaT and murine macrophage RAW264.7 cells after 24 h treatment.</p

Erratum: The second national tuberculosis prevalence survey in Vietnam (PLOS ONE (2020) 15:4 (e0232142) DOI: 10.1371/journal.pone.0232142)

In Table 1, the data and footnotes use an outdated analysis and do not correctly describe the contents of the table. Please see the correct Table 1 here. In Table 2 and Table 4, the headings Rural and Remote are swapped in the fifteenth and sixteenth rows. The fifteenth row should be Remote and the sixteenth row should be Rural. Please see the correct Table 2 and Table 4 here. (Table Presented)