Developing the Heritage Destination: An investigation of the implementation of strategic plans

This paper attempts to investigate the factors which are influential in the effective implementation of strategic planning in a heritage tourism setting. In particular, the paper looks at the respective roles of the public and private sectors in relation to creating an economically viable, augmented tourist experience from a core heritage resource, and the role of strategic planning in this process. This study is set within the context of a wider research programme which focuses on the strategic marketing planning of tourism at two heritage regions in Northern Ireland, which are made up of both publicly and privately owned resources. A conceptual model is presented, which serves to outline the marketing tasks of heritage tourism, making a distinction between strategic and operational dimensions and assigning each between public and private sectors. Findings are presented from in-depth interviews carried out with private sector tourism providers operating in the region

Dutch Treat: Netherlands Judiciary Only Goes Halfway Towards Adopting Delaware Trilogy in Takeover Context

This Note examines Dutch takeover law in light of the current inter-EU competition to attract entities to individual Member States. The recent hostile takeover of the Dutch bank, ABN AMRO, provides an excellent example of the Netherlands\u27 opportunity to use its judiciary to solidify its reputation as a competitive, business-friendly jurisdiction. The Dutch Enterprise Chamber can aid the Netherlands in becoming the preeminent EU country--a similar status to Delaware\u27s Chancery Court in the United States. Although the Enterprise Chamber attempted to introduce Delaware law in ABN AMRO, it unfortunately misapplied the law. As a result, the Dutch Supreme Court had to overrule its decision; however, the possibility of adopting Delaware takeover law remains. This Note proposes that the Dutch Enterprise Chamber adopt the Delaware takeover trilogy--Revlon, Unocal, and Unitrin--in order to provide certainty to Dutch takeover law and improve its corporate governance, which, in turn, should aid the Netherlands in attracting enterprises. Although it is too early to know, the Netherlands may become a European Delaware

Understanding the influence of place on festival making and artistic production in the local urban festival context

Recent decades have seen a dramatic increase in research output on arts festivals and cultural events, and a growing focus on the role festivals play in negotiating and constructing meanings of place. However, little attention has been paid to how place shapes the process of festival making and artistic production. This paper attempts to address this shortcoming by examining the extent to which place matters to the production of festival activity and asks: how does place influence festival making and artistic production in a local arts festival context? The study is part of ongoing qualitative research into the Five Lamps Arts Festival, a local urban festival in Dublin’s North Inner-City and employs a mixed methods approach. Findings indicate that processes of festival making and artistic production are permeated by the social, cultural, and physical dimensions of place, thereby revealing the potent and mutually inter-dependent relationship between place and festivals

Flea‘in Around: A Look at the Identification, Preservation, Clearing, and Mounting of Siphonaptera

Fleas are remarkable and highly specialized insects, with no part of their external anatomy being easily mistaken for that of any other insect. Due to their small size, the subtle differences among the distinguishing morphological characteristics of each species, and complexities of preparing specimens, identifying, and working with fleas is challenging. Various documents and taxonomic keys are available that discuss mounting procedures and the identification of medically important fleas for large regions of the world including the United States; however, many of these have become antiquated over time. Some of the distinguishing specialized characteristics exhibited among flea species, as presented in older keys, come in the form of line drawings, which are accurate but can be difficult to use when comparing it to structures on a whole specimen when viewed through a microscope. This paper presents a guide which describes in detail previously developed, but obscure techniques covering the preservation, preparation, clearing, and mounting of Siphonaptera specimens. In addition, we are also presenting an easy-to-use photographic key of twelve flea species collected from back yard wildlife, as well as pet cats and dogs in Orange County, CA. This key, which is freely available online at the Orange County Mosquito and Vector Control District’s website, is an effective tool for the identification of common flea species found in southern California. Using the key in conjunction with the mounting guide will provide users with a full-circle guide to preserving, identifying, and mounting flea specimens. Keyed flea genera include Cediopsylla, Ctenocephalides, Diamanus, Echidinophaga, Hoplopsyllus, Leptopsylla, Nosopsyllus, Orchopoeas, Pulex, and Xenopsylla. Examined hosts include cats, coyotes, dogs, mice, opossums, rabbits, raccoons, rats, skunks, squirrels, and woodrats

Do Trap-Neuter-Return (TNR) Practices Contribute to Human–Coyote Conflicts in Southern California?

One possible contributor to the unusually high number of conflicts between coyotes (Canis latrans) and people in urban southern California, USA, may be the abundance of free-roaming domestic cats (Felis catus; cats) subsidized by feeding and augmented by trap-neuter-return (TNR) programs. To determine if coyotes regularly prey on and consume cats, we combined visual and molecular-genetic approaches to identify prey items in stomachs of 311 coyotes from Los Angeles County and Orange County, provided to the South Coast Research and Extension Center, in Irvine, California, between June 2015 and December 2018. We detected cat remains in 35% of the stomachs of 245 coyotes with identifiable meals, making cats the most common mammalian prey item consumed and more common than reported previously. Using a geographic information systems approach, we then compared landscape characteristics associated with locations of coyotes that ate cats to public shelter records for TNR cat colonies. Cat-eating coyotes were associated with areas that were more intensively developed, had little natural or altered open space, and had higher building densities than coyotes that did not eat cats. Locations of TNR colonies had similar landscape characteristics. Coyotes associated with TNR colonies, and those that were euthanized (vs. road-killed), were also more likely to have consumed cats. The high frequency of cat remains in coyote diets and landscape characteristics associated with TNR colonies and cat-eating coyotes support the argument that high cat densities and associated supplemental feeding attracted coyotes. Effective mitigation of human–coyote conflicts may require prohibitions on outdoor feeding of free-roaming cats and wildlife and the elimination of TNR colonies

\u3ci\u3eEscherichia coli\u3c/i\u3e Surface Display of Single-Chain Antibody VRC01 against HIV-1 infection

Human immunodeficiency virus type 1 (HIV-1) transmission and infection occur mainly via the mucosal surfaces. The commensal bacteria residing in these surfaces can potentially be employed as a vehicle for delivering inhibitors to prevent HIV-1 infection. In this study, we have employed a bacteria-based strategy to display a broadly neutralizing antibody VRC01, which could potentially be used to prevent HIV-1 infection. The VRC01 antibody mimics CD4-binding to gp120 and has broadly neutralization activities against HIV-1. We have designed a construct that can express the fusion peptide of the scFv-VRC01 antibody together with the autotransporter β-barrel domain of IgAP gene from Neisseria gonorrhoeae, which enabled surface display of the antibody molecule. Our results indicate that the scFv-VRC01 antibody molecule was displayed on the surface of the bacteria as demonstrated by flow cytometry and immunofluorescence microscopy. The engineered bacteria can capture HIV-1 particles via surface-binding and inhibit HIV-1 infection in cell culture