2 research outputs found
Platinum(II) Complexes with Novel Diisocyanide Ligands: Catalysts in Alkyne Hydroarylation
A series of novel diisocyanide ligands
(<i>o</i>-CNC<sub>6</sub>H<sub>4</sub>O)<sub>2</sub>Y (diNC-1:
Y = PÂ(O)ÂPh; diNC-2:
Y = <i>o</i>-CÂ(O)ÂC<sub>6</sub>H<sub>4</sub>CÂ(O); diNC-3:
Y = <i>m</i>-CÂ(O)ÂC<sub>6</sub>H<sub>4</sub>CÂ(O); diNC-4:
Y = CÂ(O)ÂC<sub>2</sub>H<sub>4</sub>CÂ(O); diNC-5: Y = <i>trans</i>-CÂ(O)ÂC<sub>2</sub>H<sub>2</sub>CÂ(O)) was successfully synthesized
by reaction of lithium 2-isocyanophenate (generated in situ from benzoxazole
and <i>n</i>-BuLi) and a diacylic or phosphonic dichloride.
The corresponding platinumÂ(II) complexes of general formula [PtX<sub>2</sub>(diNC)]<sub>1,2</sub> (X = Cl, Me; diNC = diisocyanide ligand)
were isolated by simple substitution of 1,5-cyclooctadiene in the
starting [PtX<sub>2</sub>(COD)] complexes. The structure of the complexes,
mononuclear or dinuclear, was confirmed by single-crystal X-ray analysis.
A dinuclear complex of formula {(μ-diNC)Â[<i>cis</i>-PtCl<sub>2</sub>(PPh<sub>3</sub>)]<sub>2</sub>} could also be obtained
with the diisocyanide ligand having a rigid fumaryl bridge and consequently
the isocyanide moieties pointing in opposite directions. All the complexes
were employed as catalysts in the hydroarylation of alkynes, showing
generally good activity and selectivity toward the <i>trans</i>-hydroarylation product. With <i>N</i>-methylindole as
aromatic substrate the major product was instead a heterocycle:alkyne
2:1 adduct
Platinum(II) Complexes with Novel Diisocyanide Ligands: Catalysts in Alkyne Hydroarylation
A series of novel diisocyanide ligands
(<i>o</i>-CNC<sub>6</sub>H<sub>4</sub>O)<sub>2</sub>Y (diNC-1:
Y = PÂ(O)ÂPh; diNC-2:
Y = <i>o</i>-CÂ(O)ÂC<sub>6</sub>H<sub>4</sub>CÂ(O); diNC-3:
Y = <i>m</i>-CÂ(O)ÂC<sub>6</sub>H<sub>4</sub>CÂ(O); diNC-4:
Y = CÂ(O)ÂC<sub>2</sub>H<sub>4</sub>CÂ(O); diNC-5: Y = <i>trans</i>-CÂ(O)ÂC<sub>2</sub>H<sub>2</sub>CÂ(O)) was successfully synthesized
by reaction of lithium 2-isocyanophenate (generated in situ from benzoxazole
and <i>n</i>-BuLi) and a diacylic or phosphonic dichloride.
The corresponding platinumÂ(II) complexes of general formula [PtX<sub>2</sub>(diNC)]<sub>1,2</sub> (X = Cl, Me; diNC = diisocyanide ligand)
were isolated by simple substitution of 1,5-cyclooctadiene in the
starting [PtX<sub>2</sub>(COD)] complexes. The structure of the complexes,
mononuclear or dinuclear, was confirmed by single-crystal X-ray analysis.
A dinuclear complex of formula {(μ-diNC)Â[<i>cis</i>-PtCl<sub>2</sub>(PPh<sub>3</sub>)]<sub>2</sub>} could also be obtained
with the diisocyanide ligand having a rigid fumaryl bridge and consequently
the isocyanide moieties pointing in opposite directions. All the complexes
were employed as catalysts in the hydroarylation of alkynes, showing
generally good activity and selectivity toward the <i>trans</i>-hydroarylation product. With <i>N</i>-methylindole as
aromatic substrate the major product was instead a heterocycle:alkyne
2:1 adduct