Sensor location and axes orientation of the Magneto-Inertial Measurement Units (MIMUs) attached on the children’s body segments.

<p>H: head level; S: sternum level; P: pelvis.</p

Gait parameters obtained for both the TD and CP groups.

<p>Gait parameters obtained for both the TD and CP groups.</p

RMS_a inter-component relationships for the two groups (TD in light grey and CP in black).

<p>The inter-component comparison graphs characterized by significant different regression lines between the TD and CP groups are reported in figure: RMS_aAP vs RMS_aML for head (p = 0.007), RMS_aML vs RMSaCC for sternum (p = 0.048), and RMS_aAP vs RMSaCC for pelvis (p = 0.043).</p

On the left, RMS of the acceleration components at the three levels.

<p>On the right, attenuation coefficients from pelvis to head (C_PH), from pelvis to sternum (C_PS), and from sternum to head (C_SH) along the three anatomical axes. Parameters computed for the TD and CP groups are represented with empty and filled box-plots, respectively. Significant between-groups differences (p < 0.05 or p < 0.01) are reported with the symbol § or §§, respectively.</p

IPA analysis.

<p>In the figure are shown the top 6 signaling networks: 1) Cellular Movement, Hematological System Development and Function and Immune Cell Trafficking; 2) Cell Morphology, Cellular Movement, Digestive System Development and Function; 3) Free Radical Scavenging, Connective Tissue Disorders and Inflammatory Disease; 4) Cell-To-Cell Signaling and Interaction, Cellular Function and Maintenance, Hematological System Development and Function; 5) Organ Morphology, Skeletal and Muscular System Development and Function, Tissue Morphology; 6) Organ Morphology, Skeletal and Muscular System Development and Function, Cancer.</p

Gene Ontology annotation of protein.

<p>To have a general picture of the molecular functions (a), biological processes (b), and protein class (c), of identified proteins, the Protein ANalysis THrough Evolutionary Relationships (PANTHER) Database was used.</p

1d-SDS-PAGE.

<p>Proteins were resolved by Any kD Mini-PROTEAN TGX precast polyacrylamide gels. Gel line was sliced up in 7 pieces; gel bands were destained, reduced, alkylated, and digested with trypsin; peptides were resuspended and analyzed by LC-MS/MS.</p

IPA analysis.

<p>List of signaling networks associated with identified proteins.</p