Kaplan-Meier survival curves for osteosarcoma patients according to genotype for (A) rs4148416 in <i>ABCC3</i> (X² = 21.4, <i>p-value</i> = 3.8×10⁻⁶); (B) rs4148737 in <i>ABCB1</i> (X² = 18.4, <i>p-value</i> = 1.0×10⁻⁴); and (C) rs1128503 or rs10276036 in <i>ABCB1</i> (X² = 20.9, <i>p-value</i> = 2.9×10⁻⁵<i>).</i>

<p>Kaplan-Meier survival curves for osteosarcoma patients according to genotype for (A) rs4148416 in <i>ABCC3</i> (X² = 21.4, <i>p-value</i> = 3.8×10⁻⁶); (B) rs4148737 in <i>ABCB1</i> (X² = 18.4, <i>p-value</i> = 1.0×10⁻⁴); and (C) rs1128503 or rs10276036 in <i>ABCB1</i> (X² = 20.9, <i>p-value</i> = 2.9×10⁻⁵<i>).</i></p

Genes and polymorphisms associated with overall survival (OS) and event free survival (EFS).

<p>*HR: Hazard Ratio.</p><p>**Analysis adjusted for metastasis at diagnosis.</p