22,805 research outputs found
Hyperpolarized ^1H NMR employing low γ nucleus for spin polarization storage
The PASADENA (parahydrogen and synthesis allow dramatically enhanced nuclear alignment)(1, 2) and DNP (Dynamic Nuclear Polarization)(3) methods efficiently hyperpolarize biologically relevant nuclei such as 1^H, (31)^P, (13)^C, (15)^N achieving signal enhancement by a factor of ~ 100000 on currently utilized MRI scanners. Recently, many groups have demonstrated the utility of hyperpolarized MR in biological systems using hyperpolarized (13)^C biomarkers with a relatively long spin lattice relaxation time T_1 on the order of tens of seconds.(4-7) Moreover, hyperpolarized (15)^N for biomedical MR has been proposed due to even longer spin lattice relaxations times.(8) An additional increase of up to tens of minutes in the lifetime of hyperpolarized agent in vivo could be achieved by using the singlet states of low gamma (γ) nuclei.(9) However, as NMR receptivity scales as γ^3 for spin 1/2 nuclei, direct NMR detection of low γ nuclei results in a lower signal-to-noise ratio compared to proton detection. While protons are better nuclei for detection, short spin lattice relaxation times prevent direct 1^H hyperpolarized MR in biomedical applications
Polarimetric variations of binary stars. II. Numerical simulations for circular and eccentric binaries in Mie scattering envelopes
We present numerical simulations of the periodic polarimetric variations
produced by a binary star placed at the center of an empty spherical cavity
inside a circumbinary ellipsoidal and optically thin envelope made of dust
grains. Mie single-scattering is considered along with pre- and post-scattering
extinction factors which produce a time-varying optical depth and affect the
morphology of the periodic variations. We are interested in the effects that
various parameters will have on the average polarization, the amplitude of the
polarimetric variations, and the morphology of the variability. We show that
the absolute amplitudes of the variations are smaller for Mie scattering than
for Thomson scattering. Among the four grain types that we have studied, the
highest polarizations are produced by grains with sizes in the range 0.1-0.2
micron. In general, the variations are seen twice per orbit. In some cases,
because spherical dust grains have an asymmetric scattering function, the
polarimetric curves produced also show variations seen once per orbit.
Circumstellar disks produce polarimetric variations of greater amplitude than
circumbinary envelopes.
Another goal of these simulations is to see if the 1978 BME (Brown, McLean, &
Emslie, ApJ, 68, 415) formalism, which uses a Fourier analysis of the
polarimetric variations to find the orbital inclination for Thomson-scattering
envelopes, can still be used for Mie scattering. We find that this is the case,
if the amplitude of the variations is sufficient and the true inclinations is
i_true > 45 deg. For eccentric orbits, the first-order coefficients of the
Fourier fit, instead of second-order ones, can be used to find almost all
inclinations.Comment: 23 pages, 5 figures, to be published in Astronomical Journa
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Development of Container Free Sample Exposure for Synchrotron X-ray Footprinting.
The method of X-ray footprinting and mass spectrometry (XFMS) on large protein assemblies and membrane protein samples requires high flux density to overcome the hydroxyl radical scavenging reactions produced by the buffer constituents and the total protein content. Previously, we successfully developed microsecond XFMS using microfluidic capillary flow and a microfocused broadband X-ray source at the Advanced Light Source synchrotron beamlines, but the excessive radiation damage incurred when using capillaries prevented the full usage of a high-flux density beam. Here we present another significant advance for the XFMS method: the instrumentation of a liquid injection jet to deliver container free samples to the X-ray beam. Our preliminary experiments with a liquid jet at a bending magnet X-ray beamline demonstrate the feasibility of the approach and show a significant improvement in the effective dose for both the Alexa fluorescence assay and protein samples compared to conventional capillary flow methods. The combination of precisely controlled high dose delivery, shorter exposure times, and elimination of radiation damage due to capillary effects significantly increases the signal quality of the hydroxyl radical modification products and the dose-response data. This new approach is the first application of container free sample handling for XFMS and opens up the method for even further advances, such as high-quality microsecond time-resolved XFMS studies
Quasiparticle Interference on the Surface of the Topological Insulator BiTe
The quasiparticle interference of the spectroscopic imaging scanning
tunneling microscopy has been investigated for the surface states of the large
gap topological insulator BiTe through the T-matrix formalism. Both the
scalar potential scattering and the spin-orbit scattering on the warped
hexagonal isoenergy contour are considered. While backscatterings are forbidden
by time-reversal symmetry, other scatterings are allowed and exhibit strong
dependence on the spin configurations of the eigenfunctions at k points over
the isoenergy contour. The characteristic scattering wavevectors found in our
analysis agree well with recent experiment results.Comment: 5 pages, 2 figures, Some typos are correcte
A New Experiment to Study Hyperon CP Violation and the Charmonium System
Fermilab operates the world's most intense antiproton source, now exclusively
dedicated to serving the needs of the Tevatron Collider. The anticipated 2009
shutdown of the Tevatron presents the opportunity for a world-leading low- and
medium-energy antiproton program. We summarize the status of the Fermilab
antiproton facility and review physics topics for which a future experiment
could make the world's best measurements.Comment: 16 pages, 3 figures, to appear in Proceedings of CTP symposium on
Supersymmetry at LHC: Theoretical and Experimental Perspectives, The British
University in Egypt, Cairo, Egypt, 11-14 March 200
Theory of the Three Dimensional Quantum Hall Effect in Graphite
We predict the existence of a three dimensional quantum Hall effect plateau
in a graphite crystal subject to a magnetic field. The plateau has a Hall
conductivity quantized at with the
c-axis lattice constant. We analyze the three-dimensional Hofstadter problem of
a realistic tight-binding Hamiltonian for graphite, find the gaps in the
spectrum, and estimate the critical value of the magnetic field above which the
Hall plateau appears. When the Fermi level is in the bulk Landau gap, Hall
transport occurs through the appearance of chiral surface states. We estimate
the magnetic field necessary for the appearance of the three dimensional
quantum Hall Effect to be T for electron carriers and T for hole
carriers.Comment: Several new references adde
Reply to ``Comment on `Insulating Behavior of -DNA on the Micron Scale' "
In our experiment, we found that the resistance of vacuum-dried -DNA
exceeds at 295 K. Bechhoefer and Sen have raised a number of
objections to our conclusion. We provide counter arguments to support our
original conclusion.Comment: 1 page reply to comment, 1 figur
Effective mass theory of monolayer \delta-doping in the high-density limit
Monolayer \delta-doped structures in silicon have attracted renewed interest
with their recent incorporation into atomic-scale device fabrication strategies
as source and drain electrodes and in-plane gates. Modeling the physics of
\delta-doping at this scale proves challenging, however, due to the large
computational overhead associated with ab initio and atomistic methods. Here,
we develop an analytical theory based on an effective mass approximation. We
specifically consider the Si:P materials system, and the limit of high donor
density, which has been the subject of recent experiments. In this case,
metallic behavior including screening tends to smooth out the local disorder
potential associated with random dopant placement. While smooth potentials may
be difficult to incorporate into microscopic, single-electron analyses, the
problem is easily treated in the effective mass theory by means of a jellium
approximation for the ionic charge. We then go beyond the analytic model,
incorporating exchange and correlation effects within a simple numerical model.
We argue that such an approach is appropriate for describing realistic,
high-density, highly disordered devices, providing results comparable to
density functional theory, but with greater intuitive appeal, and lower
computational effort. We investigate valley coupling in these structures,
finding that valley splitting in the low-lying \Gamma band grows much more
quickly than the \Gamma-\Delta band splitting at high densities. We also find
that many-body exchange and correlation corrections affect the valley splitting
more strongly than they affect the band splitting
BoWFire: Detection of Fire in Still Images by Integrating Pixel Color and Texture Analysis
Emergency events involving fire are potentially harmful, demanding a fast and
precise decision making. The use of crowdsourcing image and videos on crisis
management systems can aid in these situations by providing more information
than verbal/textual descriptions. Due to the usual high volume of data,
automatic solutions need to discard non-relevant content without losing
relevant information. There are several methods for fire detection on video
using color-based models. However, they are not adequate for still image
processing, because they can suffer on high false-positive results. These
methods also suffer from parameters with little physical meaning, which makes
fine tuning a difficult task. In this context, we propose a novel fire
detection method for still images that uses classification based on color
features combined with texture classification on superpixel regions. Our method
uses a reduced number of parameters if compared to previous works, easing the
process of fine tuning the method. Results show the effectiveness of our method
of reducing false-positives while its precision remains compatible with the
state-of-the-art methods.Comment: 8 pages, Proceedings of the 28th SIBGRAPI Conference on Graphics,
Patterns and Images, IEEE Pres
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