Visualization 3: Intraoperative measurement of bowel oxygen saturation using a multispectral imaging laparoscope

Variation of small bowel StO2 over time during euthanasia of porcine subject. Originally published in Biomedical Optics Express on 01 October 2015 (boe-6-10-4179

Visualization 2: Intraoperative measurement of bowel oxygen saturation using a multispectral imaging laparoscope

Variation of small bowel StO2 over time during clamping and unclamping of the mesenteric arcade. Originally published in Biomedical Optics Express on 01 October 2015 (boe-6-10-4179

Media 1: Multispectral image alignment using a three channel endoscope in vivo during minimally invasive surgery

Originally published in Biomedical Optics Express on 01 October 2012 (boe-3-10-2567

Media 3: Multispectral image alignment using a three channel endoscope in vivo during minimally invasive surgery

Originally published in Biomedical Optics Express on 01 October 2012 (boe-3-10-2567

Media 2: Multispectral image alignment using a three channel endoscope in vivo during minimally invasive surgery

Originally published in Biomedical Optics Express on 01 October 2012 (boe-3-10-2567

Thermal reaction, gradual healing and complete ablation of tumour xenograft seen <i>in vivo</i> in a mouse that received IT GNRs and CW NIR laser irradiation for three minutes.

<p>The numbering indicates the days post-irradiation while the first (un-numbered) image is the pre-irradiated tumour. The irradiated site was excised at day 30 and TEM analysis is shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0185990#pone.0185990.g010" target="_blank">Fig 10(d)–10(h)</a>.</p

The measured temperature profiles from each sample with (solid lines) and without (dotted lines) CW laser irradiation using the same line colours used in Fig 1 to represent the different samples.

<p>GNR concentrations are labelled for each sample.</p

Temperature rise seen <i>in vivo</i> after intratumoural (IT) GNRs administration and during CW irradiation for three minutes measured from the tumour site externally by the thermal imaging camera, after adjusting for background and baseline temperatures.

<p>The black dashed line shows the time (180 seconds) when the laser was turned off, corresponding to when the ROI reached a 42° temperature rise.</p

Aggregation of GNRs can be observed in these TEM images (a) representing gold nanorod sample before CW laser irradiation and (b-d) after CW laser irradiation (60,000x magnification).

<p>The blue scale bars are 50 nm in length.</p

Scheme of experimental procedure of <i>in vivo</i> analysis.

<p>Scheme of experimental procedure of <i>in vivo</i> analysis.</p