36 research outputs found

    BASICS FOR A GRAPHICAL MODEL OF RISK – PERFORMANCES CORRELATION

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    A company runs a business with the goal to get a minimum level of performance.Before making an investment decision, an adequate analysis of the risk-performance correlationhas to be done. In order to emphasize the connection between these two terms, in this paper, wepropose a graphical model for analyzing the correlation between the size of the risk and the size ofthe performances. In this respect, we’ll define the performance as a function of two variables:efficiency and efficacy. The risk is considered as a function of the same variables, the efficiencyand the efficacy, and it comprises two components: the operational risk and the financial risk. Thegraphical model analyses the strategy of the company regarding the concentration of its effort onthe efficiency or the efficacy and, respectively, the correlation between the performance and therisk depending on the adopted ways.performances, risk, efficiency, degree of operating leverage, degree of financial leverage

    The Effects of Reevaluating the Balance Sheet on the Financial Standing of the Company

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    The annual financial statements of different companies must emphasize, for the internal and external users, the activity that was run and the standing at a specific moment of time. The assessment of a business doesn’t affect the accounting registrations. However, “the accurate image” provided by the book-keeping is a significant landmark for the evaluator when applying the evaluation methods. In this paper, in order to emphasize the effects of reevaluating the balance sheet on pointing out the financial standing, we have presented the calculation and the significance of the analysis indicators on a case study, before and after the reassessment operations.Financial analysis, reevaluation, financial standing, balance sheet

    THE EFFECTS OF REEVALUATING THE BALANCE SHEET ON THE FINANCIAL STANDING OF THE COMPANY

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    The annual financial statements of different companies must emphasize, for theinternal and external users, the activity that was run and the standing at a specific moment oftime. The assessment of a business doesn’t affect the accounting registrations. However, theaccurate image provided by the book-keeping is a significant landmark for the evaluatorwhen applying the evaluation methods. In this paper, in order to emphasize the effects ofreevaluating the balance sheet on pointing out the financial standing, we have presented thecalculation and the significance of the analysis indicators on a case study, before and afterthe reassessment operations.Financial analysis, reevaluation, financial standing, balance sheet

    A study regarding the risk of the micro-entreprises in the Dolj district

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    The study of the risk has become very important in the last years, due to the increase of the competition on the Romanian market and also due to the consolidation of the market economy mechanisms that have determined the augmentation of the number of bankruptcies in Romania. The micro-enterprises are, obviously, the most exposed at the risk of bankruptcy, fact that justifies a study of the risk that these enterprises face. In this paper, we have analyzed the risk of the micro-enterprises during the period 2004-2005, on a database that included 1401 companies. For this aim, we have used two specific instruments: a score function, for the estimation of the bankruptcy risk, and the degrees of leverage, for the assessment of the operating and financial risk. After making this study, we noticed that the micro-enterprises from the Dolj District have dealt with a risk augmentation in 2005, fact emphasized both by the decrease of the average score and by the augmentation of the weight of the bankrupt companies in the total number of analyzed enterprises. Also, the other drawn conclusion was linked with the lack of correlation between the Z score and the degrees of operating and financial leverage, due to the different foundations of these instruments in appreciating the risk dimension.risk, score function, degree of operating leverage, degree of financial leverage.

    USING LINEAR REGRESSION IN THE ANALYSIS OF FINANCIAL-ECONOMIC PERFORMANCES

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    Seeing that the steady pace of development and evolution of modern society has left its mark on the phenomena in all fields of activity, including in the field of economics, the analysis of financial-economic performances, as a major preoccupation of firms, has made a huge qualitative leap, by shifting the focus to the exploitation of databases (through adequate techniques) and the thorough interpretation of results. Starting from the idea that in economics, as well as in other sciences, anything has the tendency to depend on anything else, in this paper we intended to develop an econometrical model capable of expressing the relation between the economic rate of return- as a fundamental indicator of expressing the firm’s financial-economic performance- and its determinant factors. The multiple linear regression model has been developed through the analysis of data from 30 Romanian companies in the processing industry and by using the specific SPSS instruments, version 16.0.multiple linear regression model, financial-economic performances,economic rate of return

    Forecast of a quality indicator in academic activity using statistical methods

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    The paper presents the time evolution of an indicator for quality, which is related to self-evaluation of academic staff in technical faculties. The study is focused on two major issues that compose the academic activities: teaching and research activity on one side, and managerial activities on the other side. The aim of the study is to reveal the forecast of self-evaluation using statistical methods and to assess if possible, the minimum accepted value of the quality indicator

    The Effects of Reevaluating the Balance Sheet on the Financial Standing of the Company

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    The annual financial statements of different companies must emphasize, for the internal and external users, the activity that was run and the standing at a specific moment of time. The assessment of a business doesn’t affect the accounting registrations. However, “the accurate image” provided by the book-keeping is a significant landmark for the evaluator when applying the evaluation methods. In this paper, in order to emphasize the effects of reevaluating the balance sheet on pointing out the financial standing, we have presented the calculation and the significance of the analysis indicators on a case study, before and after the reassessment operations

    Human upper limb positional analysis using homogenous transformation matrix

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    A mathematical model is presented to determine the spatial displacement of an end-effector attached to the human upper limb kinematic chain. The proposed method in-volves the successive application of the homogenous rotation matrices associated with each element movement to determine the general transfer matrix or the so-called homoge-neous transformations matrix. This method is proven to be an error free method for esti-mating the position and orientation of an end-effector attached to a kinematic chain. The methodology presented in this paper combines a well know mathematical technique used in engineering (in the development of space robots) and the anatomical features of the human upper limb to estimate not only the end-effector 3D position but also the limb pos-es during a particular displacement

    Acute Hypoglycemia Induces Retinal Cell Death in Mouse

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    BACKGROUND: Glucose is the most important metabolic substrate of the retina and maintenance of normoglycemia is an essential challenge for diabetic patients. Glycemic excursions could lead to cardiovascular disease, nephropathy, neuropathy and retinopathy. A vast body of literature exists on hyperglycemia namely in the field of diabetic retinopathy, but very little is known about the deleterious effect of hypoglycemia. Therefore, we decided to study the role of acute hypoglycemia in mouse retina. METHODOLOGY/PRINCIPAL FINDINGS: To test effects of hypoglycemia, we performed a 5-hour hyperinsulinemic/hypoglycemic clamp; to exclude an effect of insulin, we made a hyperinsulinemic/euglycemic clamp as control. We then isolated retinas from each group at different time-points after the clamp to analyze cells apoptosis and genes regulation. In parallel, we used 661W photoreceptor cells to confirm in vivo results. We showed herein that hypoglycemia induced retinal cell death in mouse via caspase 3 activation. We then tested the mRNA expression of glutathione transferase omega 1 (Gsto1) and glutathione peroxidase 3 (Gpx3), two genes involved in glutathione (GSH) homeostasis. The expression of both genes was up-regulated by low glucose, leading to a decrease of reduced glutathione (GSH). In vitro experiments confirmed the low-glucose induction of 661W cell death via superoxide production and activation of caspase 3, which was concomitant with a decrease of GSH content. Moreover, decrease of GSH content by inhibition with buthionine sulphoximine (BSO) at high glucose induced apoptosis, while complementation with extracellular glutathione ethyl ester (GSHee) at low glucose restored GSH level and reduced apoptosis. CONCLUSIONS/SIGNIFICANCE: We showed, for the first time, that acute insulin-induced hypoglycemia leads to caspase 3-dependant retinal cell death with a predominant role of GSH content

    A simplified microwave-based motion detector for home cage activity monitoring in mice

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    Background: Locomotor activity of rodents is an important readout to assess well-being and physical health, and is pivotal for behavioral phenotyping. Measuring homecage-activity with standard and cost-effective optical methods in mice has become difficult, as modern housing conditions (e.g. individually ventilated cages, cage enrichment) do not allow constant, unobstructed, visual access. Resolving this issue either makes greater investments necessary, especially if several experiments will be run in parallel, or is at the animals' expense. The purpose of this study is to provide an easy, yet satisfying solution for the behavioral biologist at novice makers level. Results: We show the design, construction and validation of a simplified, low-cost, radar-based motion detector for home cage activity monitoring in mice. In addition we demonstrate that mice which have been selectively bred for low levels of anxiety-related behavior (LAB) have deficits in circadian photoentrainment compared to CD1 control animals. Conclusion: In this study we have demonstrated that our proposed low-cost microwave-based motion detector is well-suited for the study of circadian rhythms in mice
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