Column generation with dynamic duty selection for railway crew rescheduling

The Dutch railway network experiences about three large disruptions per day on average. In this paper, we present an algorithm to reschedule the crews when such a disruption occurs. The algorithm is based on column generation techniques combined with Lagrangian heuristics. Since the number of duties is very large in practical instances, we first define a core problem of tractable size. If some tasks remain uncovered in the solution of the core problem, we perform a neighborhood exploration to improve the solution. Computational experiments with real-life instances show that our method is capable of producing good solutions within a couple of minutes of Computation time

Large deviations in boundary-driven systems: Numerical evaluation and effective large-scale behavior

We study rare events in systems of diffusive fields driven out of equilibrium by the boundaries. We present a numerical technique and use it to calculate the probabilities of rare events in one and two dimensions. Using this technique, we show that the probability density of a slowly varying configuration can be captured with a small number of long wave-length modes. For a configuration which varies rapidly in space this description can be complemented by a local equilibrium assumption

Revisiting the Clinical Interpretation of CT-Measured Pulmonary Artery-to-Aorta Ratio—The Rotterdam Study

Rationale: The pulmonary artery (PA) diameter-to-aorta ratio (PA:A) ratio is a novel marker in cardiovascular imaging for detecting pulmonary hypertension. However, we question the effect of the varying aorta diameter on the ratio, which complicates the interpretation of the PA:A ratio. Objective: Investigate the variability of the PA:A ratio by examining the correlation between PA:A ratio and aorta diameter and by comparing the associations of the PA diameter, aorta diameters, and PA:A ratio. Methods: We included 2197 participants from the Rotterdam Study who underwent non-contrast multidetector computed tomography to measure the PA and aorta diameters. Pearson correlation coefficient was calculated between the PA:A ratio and aorta diameter. Multiple linear regression analyses were performed to compare the determinants of the individual diameters and PA:A ratio.Results: We found a statistically significant correlation between the PA:A ratio and aorta diameter (r = −0.38, p &lt; 0.001). The PA diameter was statistically significantly associated with, height, weight, diastolic blood pressure, blood pressure medication, prevalence of atrial fibrillation, prevalence of heart failure, and prevalence of stroke (p &lt; 0.05). Except for blood pressure medication, the PA:A ratio had similar determinants compared to the PA diameter but was also statistically significantly associated with sex, and systolic blood pressure (p &lt; 0.05), which were statistically significantly associated with the aorta diameter (p &lt; 0.05). Conclusion: The PA:A ratio should not be interpreted without taking into account the variability of the individual components (PA and aorta diameter) according to the anthropomorphic and clinical characteristics.</p

Interpersonal communication about climate change:how messages change when communicated through simulated online social networks

Climate change communication research has mainly focused on how to communicate climate change effectively to the public. By contrast, how such information is then spread through interpersonal social networks has been neglected, despite being an essential component of cultural change. Using a Facebook-like format, we examined what types of climate change messages ‘survive’ when passed between individuals via communication network chains. We found that statements centred on conventional climate change topics (e.g., its impact on the natural world and human health) survived longer in communication chains than those with less conventional topics (e.g., its impact on societal competence, development, or communality). Moreover, statements about gains from mitigation (gain-frames) survived more than those about costs of non-mitigation (loss-frames) in initial communications, but loss-framed information survived more later in communication chains. In light of research showing that climate change messages focused on society and/or gain frames can motivate action, this research highlights a challenge by showing that these messages are less likely to be spread throughout society

Strabismus measurements with novel video goggles

PURPOSE: To assess the validity of a novel, simplified, noninvasive test for strabismus using video goggles. DESIGN: Cross-sectional method comparison study in which the new test, the strabismus video goggles, is compared with the existing reference standard, the Hess screen test. PARTICIPANTS: We studied 41 adult and child patients aged ≥6 years with ocular misalignment owing to congenital or acquired paralytic or comitant strabismus and 17 healthy volunteers. METHODS: All participants were tested with binocular infrared video goggles with built-in laser target projection and liquid crystal display shutters for alternate occlusion of the eyes and the conventional Hess screen test. In both tests, ocular deviations were measured on a 9-point target grid located at 0±15° horizontal and vertical eccentricity. MAIN OUTCOME MEASURES: Horizontal and vertical ocular deviations at 9 different gaze positions of each eye were measured by the strabismus video goggles and the Hess screen test. Agreement was quantified as the intraclass correlation coefficient. Secondary outcomes were the utility of the goggles in patients with visual suppression and in children. RESULTS: There was good agreement between the strabismus video goggles and the Hess screen test in the measurements of horizontal and vertical deviation (intraclass correlation coefficient horizontal 0.83, 95% confidence interval [0.77, 0.88], vertical 0.76, 95% confidence interval [0.68, 0.82]). Both methods reproduced the characteristic strabismus patterns in the 9-point grid. In contrast to Hess screen testing, strabismus video goggle measurements were even possible in patients with comitant strabismus and visual suppression. CONCLUSIONS The new device is simple and is fast and accurate in measuring ocular deviations, and the results are closely correlated with those obtained using the conventional Hess screen test. It can even be used in patients with visual suppression who are not suitable for the Hess screen test. The device can be applied in children as young as 6 years of age

Stellar parameters for the First Release of the MaStar Library: An Empirical Approach

We report the stellar atmospheric parameters for 7503 spectra contained in the first release of the MaNGA stellar library (MaStar) in SDSS DR15. The first release of MaStar contains 8646 spectra measured from 3321 unique stars, each covering the wavelength range 3622 \AA\ to 10354 \AA\ with a resolving power of $R \sim$ 1800. In this work, we first determined the basic stellar parameters: effective temperature ($\rm T_{eff}$), surface gravity ($\log g$), and metallicity ($\rm[Fe/H]$), which best fit the data using an empirical interpolator based on the Medium-resolution Isaac Newton Telescope library of empirical spectra (MILES), as implemented by the University of Lyon Spectroscopic analysis Software (Koleva et al. 2008, ULySS) package. While we analyzed all 8646 spectra from the first release of MaStar, since MaStar has a wider parameter-space coverage than MILES, not all of these fits are robust. In addition, not all parameter regions covered by MILES yield robust results, likely due to the non-uniform coverage of the parameter space by MILES. We tested the robustness of the method using the MILES spectra itself and identified a proxy based on the local density of the training set. With this proxy, we identified 7503 MaStar spectra with robust fitting results. They cover the range from 3179K to 20,517K in effective temperature ($\rm T_{eff}$), from 0.40 to 5.0 in surface gravity ($\log g$), and from $-$2.49 to $+$0.73 in metallicity ($\rm[Fe/H]$).Comment: 14 pages, 13 figure

Synthesis and Characterization of Symmetrically versus Unsymmetrically Proton-Bridged Hexa-Iron Clusters

Syntheses and magnetic and structural characterization of hexa-iron complexes of derivatized salicylaldoximes are discussed. Complexation of Fe(BF4)2·6H2O with each ligand (H2 L1 and H4 L2) in a methanolic-pyridine solution resulted in hexa-iron compounds (C1 and C2, respectively), which each contain two near-parallel metal triangles of [Fe3-μ3-O], linked by six fluoride bridges and stabilized by a hydrogen-bonded proton between the μ3-O groups. Within each metal triangle of C2, Fe(III) ions are connected via the amine "straps" of (H4 L2-2H). Variable-temperature magnetic susceptibility and Mössbauer data of C1 and C2 indicate the presence of dominant antiferromagnetic interactions between the high-spin (S = 5/2) Fe(III) centers. For C1, two quadrupole doublets are observed at room temperature and 5 K, consistent with structural data from which discrete but disordered [Fe3-μ3-O] and [Fe3-μ3-OH] species were inferred. For C2, a single sharp quadrupole doublet with splitting intermediate between those determined for C1 was observed, consistent with the symmetric [Fe3-μ3-O···H···μ3-O-Fe3] species inferred crystallographically from the very short μ3-O···μ3-O separation. The differences in the physical properties of the complexes, as seen in the Mössbauer, X-ray, and magnetic data, are attributed to the conformational flexibility imparted by the nature of the linkages between the closely related ligands