132 research outputs found
Syntheses of 1,5-benzothiazepines: Part XVIII-Syntheses of potential, fluorinated 2,4-diaryl-8-ethoxy / fluoro-2,5-dihydro-1,5-benzothiazepines as prospective cardiovascular agents
1181-118
(E)-1-(2,5-Dimethyl-3-thienyl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one
In the title compound, C18H20O4S, the thiophene and benzene rings are oriented at a dihedral angle of 10.83 (11)°. The central chain makes dihedral angles of 1.86 (13) and 9.25 (12)° with the benzene and thiophene rings, respectively. In the crystal, molecules are linked through weak intermolecular C—H⋯O interactions. π–π interactions are also observed between the benzene rings with a centroid–centroid distance of 3.6832 (12) Å. The slippage between the benzene rings is 0.956 Å
ONE POT SYNTHESIS OF FLUORINE CONTAINING DIASTEREOISOMERiC SPIRO [3H-INDOL-3,2'-OXIRAN]-2(1H)-ONES AND THEIR CONVERSION TO 5a.1Ob-DIHYDRO-5H, 6H-INDOLO [23-b] QUINOLIN-11-ONES
One-Pot Three-Component Condensation Reaction in Water: An Efficient and Improved Procedure for the Synthesis of Pyrimido[2,1-b]benzothiazoles
Montmorillonite Catalysed Synthesis of Novel Spiro[3H-Indole-3,3′- [3H-1,2,4] Triazol]-2(1H) Ones in Dry Media under Microwave Irradiation
Synthesis of [1,2,4]Triazolo[3,4-b]Pteridines as a Novel Class of Heterocyclic Compounds
A general method for the synthesis of structurally diverse quinoxalines and pyrido-pyrazine derivatives using camphor sulfonic acid as an efficient organo-catalyst at room temperature
Synthesis of a series of 2,3-disubstituted 4H-1,4-benzothiazines and X-ray crystal structure of ethyl 7-chloro-3-methyl-4H-1,4-benzothiazine-2-carboxylate
The reaction between 2-aminobenzenethiol and ethyl acetoacetate is studied under a variety of conditions, and a procedure for the exclusive synthesis of 1,4-benzothiazines by the neat reaction of substituted aminothiols with beta-ketoesters and beta-dicarbonyl compounds in 85-96% yield is described. With microwave heating, even when both the reactants are solid, yields are high, reaction times brief, and work-up easy. A facile reaction is also observed even in a solid-state reaction. The molecular structure of ethyl 7-chloro-3-methyl-4H-1,4-benzothiazine-2-carboxylate (4d) was determined by single-crystal X-ray diffraction
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