Pair-wise analysis of the MHC class II frequencies in controls, total patients and WNND/WNF* subpopulations.

<p>P values in bold indicate significance.</p

Identification of Climatic Factors Affecting the Epidemiology of Human West Nile Virus Infections in Northern Greece - Fig 6

<p>a) For the week (W₀) the WNF/WNND case(s) occurred 41% of the cases emerged at relative humidity levels above the 10th percentile of the mean value distribution of relative humidity over the period 1979–2008. b) results for precipitation (18%), and c) soil water content (39%).</p

Pair-wise analysis of homozygous/heterozygous state in controls, total WNV cases and WNND/WNF^* subpopulations.

<p><i>P</i> values in bold indicate significance^.</p

Odds ratios for the risk of the presence of WNF/WNND human cases in association with anomalies of the mean weekly values for relative humidity, air temperature, soil water content and wind speed for the concurrent week 0 WNF/WNND human cases occurred and for time lags 1–3 weeks.

<p>Odds ratios for the risk of the presence of WNF/WNND human cases in association with anomalies of the mean weekly values for relative humidity, air temperature, soil water content and wind speed for the concurrent week 0 WNF/WNND human cases occurred and for time lags 1–3 weeks.</p

Number of WNF/WNND human cases (out of 441) above the 90th and 95th percentile for air temperature and soil temperature and the 5th and 10th percentile for precipitation, relative humidity, soil water content and wind speed of the mean value distributions over the period 1979–2008.

<p>Number of WNF/WNND human cases (out of 441) above the 90th and 95th percentile for air temperature and soil temperature and the 5th and 10th percentile for precipitation, relative humidity, soil water content and wind speed of the mean value distributions over the period 1979–2008.</p

Degree of agreement plot for the air temperature weekly anomalies obtained from the difference of the period 1979–2008 vs. 2010–2014.

<p>The difference of NCDC and ERAI against their average and the 2SD range are plotted.</p

Plots show the air temperature anomalies in August 2009 compared with those of August 2010 the year the first and largest outbreak of WNV infections in Greece.

<p>Plots show the air temperature anomalies in August 2009 compared with those of August 2010 the year the first and largest outbreak of WNV infections in Greece.</p

The official nomenclature of the identified alleles and their frequency in European populations together with the respective allelic frequencies found in this study (column Greece) [24].

<p>The official nomenclature of the identified alleles and their frequency in European populations together with the respective allelic frequencies found in this study (column Greece) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0165952#pone.0165952.ref024" target="_blank">24</a>].</p

Number of reported WNF/WNND cases in humans for the period 2010–2014 in Northern Greece.

<p>Number of reported WNF/WNND cases in humans for the period 2010–2014 in Northern Greece.</p

Geographic distribution of the WNF/WNND cases in humans observed during the period 2010–2014 in Northern Greece (triangles) and the grid defined to retrieve the climatic factors based on ERA-Interim (black spots grid).

<p>Red triangles represent the neuro-invasive WNND human cases; yellow triangles other milder human cases of WNF; cyan spots mark location of the mosquito traps. (OpenStreetMap software (<a href="http://www.openstreetmap.org/" target="_blank">http://www.openstreetmap.org</a>)</p