Association between patient characteristics and clusters [n(%) or Mean (SD)].

<p>Association between patient characteristics and clusters [n(%) or Mean (SD)].</p

Longitudinal models of lung function and current severity proxies.

<p>Longitudinal models of lung function and current severity proxies.</p

Comparison of factors between clusters.

<p>Cluster 1 had significantly lower composite scores than Clusters 2 or 3 (p<0.0001). Cluster 3 had significantly lower PFT, VO₂m + WLM composites than Cluster 2 (p<0.0001).</p

Association between lung function and clusters.

<p>Association between lung function and clusters.</p

Factors and loadings for standardized outcome estimates at 30 years.

<p>Factors and loadings for standardized outcome estimates at 30 years.</p

CBD patient population demographics and clinical results (N = 207).

<p>CBD patient population demographics and clinical results (N = 207).</p

Population characteristics by high-risk autoantibody profile (HRP) phenotype in 257 serum/plasma samples from clinic visits of 144 FDRs from the studies of the Etiology of rheumatoid arthritis (SERA) cohort.

<p>Population characteristics by high-risk autoantibody profile (HRP) phenotype in 257 serum/plasma samples from clinic visits of 144 FDRs from the studies of the Etiology of rheumatoid arthritis (SERA) cohort.</p

Median (25th, 75th Percentile)^* levels of adiponectin and inflammatory markers by high-risk autoantibody profile (HRP) phenotype in 257 serum/plasma samples from clinic visits of 144 FDRs from the studies of the Etiology of rheumatoid arthritis (SERA) cohort.

<p>Median (25th, 75th Percentile)^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0199578#t002fn001" target="_blank">*</a>} levels of adiponectin and inflammatory markers by high-risk autoantibody profile (HRP) phenotype in 257 serum/plasma samples from clinic visits of 144 FDRs from the studies of the Etiology of rheumatoid arthritis (SERA) cohort.</p

Modification of the association between adiponectin and inflammatory markers (A through H) by HRP status using linear mixed models in the studies of the Etiology of rheumatoid arthritis.

<p>This figure presents the interaction between adiponectin and High-Risk profile autoantibody (HRP) status in 257 serum and plasma samples from clinic visits of 144 first degree-relatives of RA patients in the Studies of the Etiology of Rheumatoid Arthritis. All analyses were adjusted for age, sex, ethnicity, BMI, pack-years of smoking, and current use of cholesterol-lowering medications.</p

Association between adiponectin and markers of inflammation in 257 serum/plasma samples from clinic visits of 144 FDRs from the studies of the Etiology of rheumatoid arthritis (SERA) cohort.

<p>Association between adiponectin and markers of inflammation in 257 serum/plasma samples from clinic visits of 144 FDRs from the studies of the Etiology of rheumatoid arthritis (SERA) cohort.</p