Progenitor constraints on the Type-Ia supernova SN2011fe from pre-explosion Hubble Space Telescope HeII narrow-band observations

We present Hubble Space Telescope (HST) imaging observations of the site of the Type-Ia supernova SN2011fe in the nearby galaxy M101, obtained about one year prior to the event, in a narrow band centred on the HeII 4686 \AA{} emission line. In a "single-degenerate" progenitor scenario, the hard photon flux from an accreting white dwarf (WD), burning hydrogen on its surface over $\sim1$ Myr should, in principle, create a HeIII Str\"{o}mgren sphere or shell surrounding the WD. Depending on the WD luminosity, the interstellar density, and the velocity of an outflow from the WD, the HeIII region could appear unresolved, extended, or as a ring, with a range of possible surface brightnesses. We find no trace of HeII 4686 \AA{} line emission in the HST data. Using simulations, we set $2\sigma$ upper limits on the HeII 4686 \AA{} luminosity of $L_{\rm HeII} < 3.4 \times 10^{34}$ erg s$^{-1}$ for a point source, corresponding to an emission region of radius $r < 1.8$ pc. The upper limit for an extended source is $L_{\rm HeII} < 1.7 \times 10^{35}$ erg s$^{-1}$, corresponding to an extended region with $r\sim11$ pc. The largest detectable shell, given an interstellar-medium density of 1 cm$^{-3}$, has a radius of $\sim6$ pc. Our results argue against the presence, within the $\sim10^5$ yr prior to the explosion, of a supersoft X-ray source of luminosity $L_{\rm bol} \ge 3 \times 10^{37}$ erg s$^{-1}$, or of a super-Eddington accreting WD that produces an outflowing wind capable of producing cavities with radii of 2-6 pc.Comment: Accepted by MNRAS Letters; revised version following referee report and readers' comment

The multiple personalities of Watson and Crick strands

<p>Abstract</p> <p>Background</p> <p>In genetics it is customary to refer to double-stranded DNA as containing a "Watson strand" and a "Crick strand." However, there seems to be no consensus in the literature on the exact meaning of these two terms, and the many usages contradict one another as well as the original definition. Here, we review the history of the terminology and suggest retaining a single sense that is currently the most useful and consistent.</p> <p>Proposal</p> <p>The <it>Saccharomyces </it>Genome Database defines the Watson strand as the strand which has its 5'-end at the short-arm telomere and the Crick strand as its complement. The Watson strand is always used as the reference strand in their database. Using this as the basis of our standard, we recommend that Watson and Crick strand terminology only be used in the context of genomics. When possible, the centromere or other genomic feature should be used as a reference point, dividing the chromosome into two arms of unequal lengths. Under our proposal, the Watson strand is standardized as the strand whose 5'-end is on the short arm of the chromosome, and the Crick strand as the one whose 5'-end is on the long arm. Furthermore, the Watson strand should be retained as the reference (plus) strand in a genomic database. This usage not only makes the determination of Watson and Crick unambiguous, but also allows unambiguous selection of reference stands for genomics.</p> <p>Reviewers</p> <p>This article was reviewed by John M. Logsdon, Igor B. Rogozin (nominated by Andrey Rzhetsky), and William Martin.</p

Spectroscopic identification of a redshift 1.55 supernova host galaxy from the Subaru Deep Field Supernova Survey

Context: The Subaru Deep Field (SDF) Supernova Survey discovered 10 Type Ia supernovae (SNe Ia) in the redshift range 1.5<z<2.0, as determined solely from photometric redshifts of the host galaxies. However, photometric redshifts might be biased, and the SN sample could be contaminated by active galactic nuclei (AGNs). Aims: We aim to obtain the first robust redshift measurement and classification of a z > 1.5 SDF SN Ia host galaxy candidate Methods: We use the X-shooter (U-to-K-band) spectrograph on the Very Large Telescope to allow the detection of different emission lines in a wide spectral range. Results: We measure a spectroscopic redshift of 1.54563 +/- 0.00027 of hSDF0705.25, consistent with its photometric redshift of 1.552 +/- 0.018. From the strong emission-line spectrum we rule out AGN activity, thereby confirming the optical transient as a SN. The host galaxy follows the fundamental metallicity relation defined in Mannucci et al. (2010, 2011) showing that the properties of this high-redshift SN Ia host galaxy is similar to other field galaxies. Conclusions: Spectroscopic confirmation of additional SDF SN hosts would be required to confirm the cosmic SN rate evolution measured in the SDF.Comment: 14 pages, 2 figures, Accepted A&A Upload of the Journal versio

Is There a Twelfth Protein-Coding Gene in the Genome of Influenza A? A Selection-Based Approach to the Detection of Overlapping Genes in Closely Related Sequences

Protein-coding genes often contain long overlapping open-reading frames (ORFs), which may or may not be functional. Current methods that utilize the signature of purifying selection to detect functional overlapping genes are limited to the analysis of sequences from divergent species, thus rendering them inapplicable to genes found only in closely related sequences. Here, we present a method for the detection of selection signatures on overlapping reading frames by using closely related sequences, and apply the method to several known overlapping genes, and to an overlapping ORF on the negative strand of segment 8 of influenza A virus (NEG8), for which the suggestion has been made that it is functional. We find no evidence that NEG8 is under selection, suggesting that the intact reading frame might be non-functional, although we cannot fully exclude the possibility that the method is not sensitive enough to detect the signature of selection acting on this gene. We present the limitations of the method using known overlapping genes and suggest several approaches to improve it in future studies. Finally, we examine alternative explanations for the sequence conservation of NEG8 in the absence of selection. We show that overlap type and genomic context affect the conservation of intact overlapping ORFs and should therefore be considered in any attempt of estimating the signature of selection in overlapping gene