Additional file 2: Figure S1. of Exaggerated CpH methylation in the autism-affected brain

Detecting sample outliers. Figure S2. Null distributions. Figure S3. Published meQTLs help identify sample outliers. Figure S4. Cytosine summary. Figure S5. Percent methylation. Figure S6. Correlation between RRBS and 27K array data. Figure S7. Single-site differential methylation analysis. Figure S8. Methylation patterns at previously reported DMRs. Figure S9. Hypermethylation signal in CpH sites increases with methylation difference between cases and controls. Figure S10. Functional enrichment testing at histone marks from a lympoblastoid cell line (LCL). Figure S11. Power calculation curve. (PPTX 1789 kb

Additional file 3: of Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Video S1. (Quicktime) Video to illustrate the DORV phenotype finding in an Adamts6 mutant heart. (MOV 1983 kb

Additional file 2: of Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Figure S1. Manhattan plot for European and African-American ancestry single variant analysis. Figure S2. Quantile-quantile plot for European and African-American ancestry single variant analysis. Figure S3. Manhattan plot for EA single variant analysis. Figure S4. QQ plot for EA single variant analysis. Figure S5. Manhattan plot for AA single variant analysis. Figure S6. Quantile-quantile plot for AA single variant analysis. Figure S7. Miami plot European and African-American ancestry sex-stratified single variant analysis. Figure S8. Quantile-quantile plots for European and African-American ancestry sex-stratified single variant analyses. Figure S9. Normal morphology of adult Adamts6 heterozygous hearts. (DOCX 4290 kb