7,828 research outputs found
Design of an integrated shallow water wave experiment
The experimental design and instrumentation for an integrated shallow-water surface gravity wave experiment is discussed. The experiment required the measurement of the water surface elevation, meteorological parameters, and directional spectra at a number of locations on a shallow lake. In addition, to acquire data under a wide range of conditions, an experimental period of three years was required. A system of telephone and radio modem links were installed to enable real-time monitoring of instrument performance at eight separate measurement locations on the lake. This system also enabled logging sessions to be optimized to ensure the maximum possible data return from this extended experimentIEEE Oceanic Engineering Societ
Synchronized pulse control of decoherence
We present a new strategy for multipulse control over decoherence. When a
two-level system interacts with a reservoir characterized by a specific
frequency, we find that the decoherence is effectively suppressed by
synchronizing the pulse-train application with the dynamical motion of the
reservoir.Comment: 14 pages, 8 figure
Decoherence Rates in Large Scale Quantum Computers and Macroscopic Systems
Markovian regime decoherence effects in quantum computers are studied in
terms of the fidelity for the situation where the number of qubits N becomes
large. A general expression giving the decoherence time scale in terms of
Markovian relaxation elements and expectation values of products of system
fluctuation operators is obtained, which could also be applied to study
decoherence in other macroscopic systems such as Bose condensates and
superconductors. A standard circuit model quantum computer involving
three-state lambda system ionic qubits is considered, with qubits localised
around well-separated positions via trapping potentials. The centre of mass
vibrations of the qubits act as a reservoir. Coherent one and two qubit gating
processes are controlled by time dependent localised classical electromagnetic
fields that address specific qubits, the two qubit gating processes being
facilitated by a cavity mode ancilla, which permits state interchange between
qubits. With a suitable choice of parameters, it is found that the decoherence
time can be made essentially independent of N.Comment: Minor revisions. To be published in J Mod Opt. One figur
Asymmetric double-well potential for single atom interferometry
We consider the evolution of a single-atom wavefunction in a time-dependent
double-well interferometer in the presence of a spatially asymmetric potential.
We examine a case where a single trapping potential is split into an asymmetric
double well and then recombined again. The interferometer involves a
measurement of the first excited state population as a sensitive measure of the
asymmetric potential. Based on a two-mode approximation a Bloch vector model
provides a simple and satisfactory description of the dynamical evolution. We
discuss the roles of adiabaticity and asymmetry in the double-well
interferometer. The Bloch model allows us to account for the effects of
asymmetry on the excited state population throughout the interferometric
process and to choose the appropriate splitting, holding and recombination
periods in order to maximize the output signal. We also compare the outcomes of
the Bloch vector model with the results of numerical simulations of the
multi-state time-dependent Schroedinger equation.Comment: 9 pages, 6 figure
Patient-Reported Outcomes Measurement Information System physical function correlates with Toronto Extremity Salvage Score in an orthopaedic oncology population
Background: The National Institute of Health\u27s Patient-Reported Outcomes Measurement Information System (PROMIS) uses computerised-adaptive testing to reduce survey burden and improve sensitivity. PROMIS is being used across medical and surgical disciplines but has not been studied in orthopaedic oncology.
Questions/purposes: The aim of the study was to compare PROMIS measures with upper extremity (UE) and lower extremity (LE) Toronto Extremity Salvage Score (TESS) by assessing the following: (1) responder burden, (2) correlation between scores and (3) floor/ceiling effects.
Patients and methods: This cross-sectional trial analysed all 97 adult patients treated surgically for a bone or soft tissue tumour at a tertiary institution between November 2015 and March 2016. TESS (UE or LE) and PROMIS (Physical Function, Pain Interference and Depression) surveys were administered preoperatively. Pearson correlations between each PROMIS domain and TESS were calculated, as were floor/ceiling effects of each outcome measure.
Results: (1) Completion of three PROMIS questionnaires required a mean total of 16.8 (+/- 5.8 standard deviation) questions, compared with 31 and 32 questions for the LE and UE TESS questionnaires, respectively. (2) The PROMIS Physical Function scores demonstrated a strong positive correlation with the LE TESS (r = 0.84; 95% confidence interval [CI], 0.72-0.91; p \u3c 0.001) and moderate positive correlation with the UE TESS (r = 0.64; 95% CI, 0.34-0.83; p = 0.055). The PROMIS Depression scores demonstrated a weak negative correlation with both the LE TESS (r = -0.38; 95% CI, -0.61 to -0.10; p = 0.010) and with UE TESS (r = -0.38; 95% CI, -0.67 to -0.01; p = 0.055). The PROMIS Pain Interference scores demonstrated a strong negative correlation with the LE TESS (r = -0.71; 95% CI, -0.83 to -0.52; p \u3c 0.001) and a moderate negative correlation with the UE TESS (r = -0.62; 95% CI, -0.81 to -0.30; p = 0.001). (3) The UE TESS had a range of scores from 16 to 100 with a 27% ceiling effect and no floor effect, and the LE TESS had a range from 10 to 98 with no floor or ceiling effect. There was no floor or ceiling effect for any PROMIS measures.
Conclusions: In an orthopaedic oncology population, the PROMIS Physical Function and Pain Interference scores correlate with the TESS and have the benefit of reduced survey burden and ceiling effect. The PROMIS Depression scores may provide additional information regarding patient outcomes not captured by the TESS.
Level of Evidence: Level III.
The translational potential of this article: Patient reported outcome measures asses patients\u27 symptoms, function and health-related quality of life and are designed to capture more clinical information than can be gathered by objective medial testing alone. As reimbursements and the understanding of patient outcomes are becoming tied to performance on PROMIS measures, it is an important step to establish how PROMIS measures correlate and compare to traditional legacy measures
Immune response impairs learning in free-flying bumble-bees
Parasites can influence different host behaviours including foraging, mate choice and predator avoidance. Several recent papers have shown reduced learning abilities in infected insects. However, it is difficult to separate the effects of the immune response from the direct effects of the parasite. Using a free-flying learning paradigm, this paper shows that learning performance is impaired in bumble-bees (Bombus terrestris) that are not infected but whose immune system is stimulated non-pathogenically. This demonstrates that before it is assumed that a parasite has a direct effect on a host's behaviour, the effect of the immune response stimulated by the parasite must first be quantified
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