Over-represented motifs in genes upregulated in WT at 13.5 d.p.c.

<p>Over-represented motifs in genes upregulated in WT at 13.5 d.p.c.</p

Top 20 PIF at 13.5 d.p.c.

<p>* The top 20 PIF scores with a q-value < 0.10 are presented. For multiple probesetIDs with the same annotation, the probesetID with smallest q-value was saved.</p><p>^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117607#t008fn001" target="_blank">*</a>}</p

KEGG pathway analysis of genes highly correlated with <i>Myl3</i> at d35 in wild-type vs. MSTN-null mice.

<p>KEGG pathway analysis of genes highly correlated with <i>Myl3</i> at d35 in wild-type vs. MSTN-null mice.</p

Top 20 PIF at d35^*.

<p>*The top 20 PIF scores with a q-value < 0.10 are presented. For multiple probesetIDs with the same annotation, the probesetID with smallest q-value was saved.</p><p>Top 20 PIF at d35^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117607#t009fn001" target="_blank">*</a>}.</p

Top 20 WT/null differentially expressed genes ranked by significance at d35, q < 0.05^*.

<p>*For multiple probesetIDs with the same annotation, the probesetID with smallest q-value was saved.</p><p>^{^}Fold changes are presented as WT/null. Fold change > 1 indicates higher expression in the WT compared to the null. Fold change < 1 indicates higher expression in the null genotype compared to the WT.</p><p>Top 20 WT/null differentially expressed genes ranked by significance at d35, q < 0.05^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117607#t002fn001" target="_blank">*</a>}.</p

Over-represented motifs in genes upregulated in MSTN-null at 13.5 d.p.c.

<p>Over-represented motifs in genes upregulated in MSTN-null at 13.5 d.p.c.</p

Heat map of genes highly correlated to <i>Myl3</i> in WT and MSTN-null mice at d35.

<p>Heat map of genes highly correlated to <i>Myl3</i> in WT and MSTN-null mice at d35.</p

Differential wiring of co-correlated genes between WT and MSTN-null mice (|r| ≥ 0.9).

<p>Differential wiring of co-correlated genes between WT and MSTN-null mice (|r| ≥ 0.9).</p

Relationship between RIF1 and RIF2 at 13.5 d.p.c. and d35.

<p>Relationship between RIF1 and RIF2 at 13.5 d.p.c. and d35.</p

Top 20 WT/null differentially expressed genes ranked by significance at 13.5 d.p.c., q < 0.05^*.

<p>*For multiple probesetIDs with the same annotation, the probesetID with smallest q-value was saved.</p><p>^{^}Fold changes are presented as WT/null. Fold change > 1 indicates higher expression in the WT compared to the null. Fold change < 1 indicates higher expression in the null genotype compared to the WT.</p><p>Top 20 WT/null differentially expressed genes ranked by significance at 13.5 d.p.c., q < 0.05^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0117607#t001fn001" target="_blank">*</a>}.</p