222 research outputs found

    Who is the Attorney General\u27s Client

    Get PDF
    The article discusses a court case of Free Enterprise Fund v. Public Co. Accounting Oversight Board recently decided by the U.S. Supreme Court based on the role of the U.S. President in the faithful execution of laws. The role of the Attorney General, client relationship and its historical considerations are discussed. The obligations of executive branch, plausible alternative and the role of President in setting of legal policy are also discussed

    Who is the Attorney General\u27s Client

    Get PDF
    The article discusses a court case of Free Enterprise Fund v. Public Co. Accounting Oversight Board recently decided by the U.S. Supreme Court based on the role of the U.S. President in the faithful execution of laws. The role of the Attorney General, client relationship and its historical considerations are discussed. The obligations of executive branch, plausible alternative and the role of President in setting of legal policy are also discussed

    The Impact of Situational Elements Upon an Internship Director\u27s Supervisory Style: A Model

    Get PDF
    This article argues that internship directors must examine the constraints and objectives of their program and then select an appropriate supervisory style in order to be effective. Considering the many benefits associated with the internship experience, it is not surprising that over one thousand colleges and universities in the U.S. offer some type of internship program. What is surprising is that internship directors looking for suggestions on internship administration find little research devoted to developing effective administrative decisions. The relationship between the intern, the faculty coordinator, and the site supervisor may be of a helping nature whereby the faculty coordinator consults with and advises the intern with the hope of improving the intern\u27s understanding of the communication principles operating in the internship. Some directors, on the other hand, may feel that learning is the responsibility of the student, hence the particular workplace becomes the primary locus of education through the internship

    Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 13: Injection therapies, low-back pain, and lumbar fusion

    Get PDF
    pre-printThe medical literature continues to fail to support the use of lumbar epidural injections for long-term relief of chronic back pain without radiculopathy. There is limited support for the use of lumbar epidural injections for short-term relief in selected patients with chronic back pain. Lumbar intraarticular facet injections are not recommended for the treatment of chronic lower-back pain. The literature does suggest the use of lumbar medial nerve blocks for short-term relief of facet-mediated chronic lower-back pain without radiculopathy. Lumbar medial nerve ablation is suggested for 3-6 months of relief for chronic lower-back pain without radiculopathy. Diagnostic medial nerve blocks by the double-injection technique with an 80% improvement threshold are an option to predict a favorable response to medial nerve ablation for facet-mediated chronic lower-back pain without radiculopathy, but there is no evidence to support the use of diagnostic medial nerve blocks to predict the outcomes in these same patients with lumbar fusion. There is insufficient evidence to support or refute the use of trigger point injections for chronic lower-back pain without radiculopathy

    The Health Status of Southern Children: A Neglected Regional Disparity

    Full text link
    Purpose: Great variations exist in child health outcomes among states in the United States, with southern states consistently ranked among the lowest in the country. Investigation of the geographical distribution of children’s health status and the regional factors contributing to these outcomes has been neglected. We attempted to identify the degree to which region of residence may be linked to health outcomes for children with the specific aim of determining whether living in the southern region of the United States is adversely associated with children’s health status. Methods: A child health index (CHI) that ranked each state in the United States was computed by using statespecific composite scores generated from outcome measures for a number of indicators of child health. Five indicators for physical health were chosen (percent low birth weight infants, infant mortality rate, child death rate, teen death rate, and teen birth rates) based on their historic and routine use to define health outcomes in children. Indicators were calculated as rates or percentages. Standard scores were calculated for each state for each health indicator by subtracting the mean of the measures for all states from the observed measure for each state. Indicators related to social and economic status were considered to be variables that impact physical health, as opposed to indicators of physical health, and therefore were not used to generate the composite child health score. These variables were subsequently examined in this study as potential confounding variables. Mapping was used to redefine regional groupings of states, and parametric tests (2-sample t test, analysis of means, and analysis-of-variance F tests) were used to compare the means of the CHI scores for the regional groupings and test for statistical significance. Multiple regression analysis computed the relationship of region, social and economic indicators, and race to the CHI. Simple linear-regression analyses were used to assess the individual effect of each indicator. Results: A geographic region of contiguous states, characterized by their poor child health outcomes relative to other states and regions of the United States, exists within the “Deep South” (Mississippi, Louisiana, Arkansas, Tennessee, Alabama, Georgia, North Carolina, South Carolina, and Florida). This Deep-South region is statistically different in CHI scores from the US Census Bureau– defined grouping of states in the South. The mean of CHI scores for the Deep-South region was \u3e1 SD below the mean of CHI scores for all states. In contrast, the CHI score means for each of the other 3 regions were all above the overall mean of CHI scores for all states. Regression analysis showed that living in the Deep- South region is a stronger predictor of poor child health outcomes than other consistently collected and reported variables commonly used to predict children’s health. Conclusions: The findings of this study indicate that region of residence in the United States is statistically related to important measures of children’s health and may be among the most powerful predictors of child health outcomes and disparities. This clarification of the poorer health status of children living in the Deep South through spatial analysis is an essential first step for developing a better understanding of variations in the health of children. Similar to early epidemiology work linking geographic boundaries to disease, discovering the mechanisms/pathways/causes by which region influences health outcomes is a critical step in addressing disparities and inequities in child health and one that is an important and fertile area for future research. The reasons for these disparities may be complex and synergistically related to various economic, political, social, cultural, and perhaps even environmental (physical) factors in the region. This research will require the use and development of new approaches and applications of spatial analysis to develop insights into the societal, environmental, and historical determinants of child health that have been neglected in previous child health outcomes and policy research. The public policy implications of the findings in this study are substantial. Few, if any, policies identify these children as a high-risk group on the basis of their region of residence. A better understanding of the depth and breadth of disparities in health, education, and other social outcomes among and within regions of the United States is necessary for the generation of policies that enable policy makers to address and mitigate the factors that influence these disparities. Defining and clarifying the regional boundaries is also necessary to better inform public policy decisions related to resource allocation and the prevention and/or mitigation of the effects of region on child health. The identification of the Deep South as a clearly defined sub-region of the Census Bureau’s regional definition of the South suggests the need to use more culturally and socially relevant boundaries than the Census Bureau regions when analyzing regional data for policy development

    Chamber free fusion welding root side purging method and apparatus

    Get PDF
    A method and apparati are presented for non-chamber root side purging in fusion welding of oxygen reactive metals which require that the molten weld zone and local solid areas of the weld seam remaining at high temperatures be shielded from normal atmosphere to prevent degradation of the welded area. The apparati provide an inert atmosphere to the root side of a weld joint through a porous medium whereby the jet-like thrust of the plasma arc actually draws the continuously supplied inert atmosphere into the path of the molten or high temperature solid weld zone. The porous medium is configured so it can be placed at the borders of the weld seam and substantially parallel to the seam without restricting the view of the root side of the seam. The inert gas is dispersed evenly through the porous media and across the weld seam, at the point of arc penetration and in front of and behind the arc. The apparati can be constructed so as to limit the amount of inert gas flow and can be mobile and travel synchronously with the welding arc

    The Iowa Homemaker vol.37, no.5

    Get PDF
    One Flight Down to Fantasy, William Smith, page 4 Sophisticate Your Old Favorite, Diane Rasmussen, page 6 Be Letter Perfect, Laura Dailey, page 7 Creating – From-me-to-you messages, Corky Allbee, page 8 They Taught Us to Read, Amelia Caulker, page 11 Color Reactions, Carole Boughton, page 13 Let’s Keep Christmas, Condensed from sermon by Peter Marshall, page 1

    Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites.

    Get PDF
    Voltage-gated sodium (NaV) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic NaV channel NaChBac have demonstrated that propofol promotes channel activation and accelerates activation-coupled inactivation, but the molecular mechanisms of these effects are unclear. Here, guided by computational docking and molecular dynamics simulations, we predict several propofol-binding sites in NaChBac. We then strategically place small fluorinated probes at these putative binding sites and experimentally quantify the interaction strengths with a fluorinated propofol analogue, 4-fluoropropofol. In vitro and in vivo measurements show that 4-fluoropropofol and propofol have similar effects on NaChBac function and nearly identical anesthetizing effects on tadpole mobility. Using quantitative analysis by 19F-NMR saturation transfer difference spectroscopy, we reveal strong intermolecular cross-relaxation rate constants between 4-fluoropropofol and four different regions of NaChBac, including the activation gate and selectivity filter in the pore, the voltage sensing domain, and the S4-S5 linker. Unlike volatile anesthetics, 4-fluoropropofol does not bind to the extracellular interface of the pore domain. Collectively, our results show that propofol inhibits NaChBac at multiple sites, likely with distinct modes of action. This study provides a molecular basis for understanding the net inhibitory action of propofol on NaV channels. © 2018 Wang et al

    Rowing Against the Tide: Getting Landowners to Manage Habitat for Their Favorite Wildlife Species, Bobwhites

    Get PDF
    A primary cause of the decline of northern bobwhite (Colinus virginianus) is that landowners often lack adequate motivation for the arduous task of creating and managing habitat. We gained insight into some of these motivations through survey questionnaires and focus groups in Missouri, and report findings from 3 studies containing 3,057 survey responses during 2004–2007. One of the surveys targeted Conservation Reserve Program (CRP) lands (‘CRP survey’), another lands with potential for bobwhite restoration (‘bobwhite survey’), and the third focused on grassland bird restoration. Landowners in each survey identified bobwhites as the most popular (.80% of respondents chose ‘somewhat’ or ‘very’ ‘important’ to have bobwhites ‘on my land’) natural resource among a list that included deer, turkeys, prairie-chickens, native plants, grassland birds, rabbits, hawks/owls, etc. Bobwhites were highly valued by landowners, but other answers in these surveys revealed many obstacles to habitat management including economics, time, knowledge, skill, and equipment. For example, only 39% of respondents in the bobwhite survey were interested in joining a habitat restoration cooperative, and ,50% of respondents in all surveys were willing to adopt quail-friendly habitat management (prescribed fire, disking, herbicides, moderate grazing, native vegetation, presence of weeds, etc.). Bobwhite restoration programs, because of the gap between landowners’ fondness for quail, but being less willing to take action, must include a comprehensive approach, ranging from local community involvement by agency biologists and non-government organizations to resource-use policy in Washington, D.C
    • 

    corecore