Ethical dilemmas encountered during clinical drug trials

Ethical standards have a basis in antiquity and changes in practice need to be measured by moral considerations that are slower to change. This paper considers present day ethical problems in clinical trials-especially in infection, conflict of interest, financing of scientific studies and publishing (or non-publishing) of the results. (C) 2004 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved