82 research outputs found

    Signature of coexistence of superconductivity and ferromagnetism in two-dimensional NbSe\u3csub\u3e2\u3c/sub\u3e triggered by surface molecular adsorption

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    Ferromagnetism is usually deemed incompatible with superconductivity. Consequently, the coexistence of superconductivity and ferromagnetism is usually observed only in elegantly designed multi-ingredient structures in which the two competing electronic states originate from separate structural components. Here we report the use of surface molecular adsorption to induce ferromagnetism in two-dimensional superconducting NbSe2, representing the freestanding case of the coexistence of superconductivity and ferromagnetism in one two-dimensional nanomaterial. Surface-structural modulation of the ultrathin superconducting NbSe2 by polar reductive hydrazine molecules triggers a slight elongation of the covalent Nb–Se bond, which weakens the covalent interaction and enhances the ionicity of the tetravalent Nb with unpaired electrons, yielding ferromagnetic ordering. The induced ferromagnetic momentum couples with conduction electrons generating unique correlated effects of intrinsic negative magnetoresistance and the Kondo effect. We anticipate that the surface molecular adsorption will be a powerful tool to regulate spin ordering in the two-dimensional paradigm

    Study on the breakdown characteristics of multiple-reignition secondary arcs on EHV/UHV transmission lines

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    A long-gap AC arc with a length of more than ten meters (secondary arc) are normally generated at the short-circuit arc channel after a single-phase-to-ground fault. In previous studies, arc breakdowns of secondary arcs have mainly been considered as electrical breakdowns, ignoring the role of heat in the arc channel. Besides, the extinction-reignition theory of secondary arc, i.e., dielectric strength recovery theory, still lack the support of experimental data. In this study, based on the equivalent experiments performed in the laboratory, the influences of compensation degree of transmission lines, initial recovery voltage gradient of air gap, test current, wind speed, and wind direction on the breakdown characteristics of secondary arcs are studied and statistically analyzed. The laws of the transient recovery voltage (TRV) and of the rate of rise of recovery voltage (RRRV) also studied by considering the influencing factors mentioned above. The results of this study will provide a more complete experimental basis for the theory of extinction–reignition of secondary arcs and a deeper understanding of the transient characteristics of arc breakdow

    Methylprednisolone as Adjunct to Endovascular Thrombectomy for Large-Vessel Occlusion Stroke

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    Importance It is uncertain whether intravenous methylprednisolone improves outcomes for patients with acute ischemic stroke due to large-vessel occlusion (LVO) undergoing endovascular thrombectomy. Objective To assess the efficacy and adverse events of adjunctive intravenous low-dose methylprednisolone to endovascular thrombectomy for acute ischemic stroke secondary to LVO. Design, Setting, and Participants This investigator-initiated, randomized, double-blind, placebo-controlled trial was implemented at 82 hospitals in China, enrolling 1680 patients with stroke and proximal intracranial LVO presenting within 24 hours of time last known to be well. Recruitment took place between February 9, 2022, and June 30, 2023, with a final follow-up on September 30, 2023.InterventionsEligible patients were randomly assigned to intravenous methylprednisolone (n = 839) at 2 mg/kg/d or placebo (n = 841) for 3 days adjunctive to endovascular thrombectomy. Main Outcomes and Measures The primary efficacy outcome was disability level at 90 days as measured by the overall distribution of the modified Rankin Scale scores (range, 0 [no symptoms] to 6 [death]). The primary safety outcomes included mortality at 90 days and the incidence of symptomatic intracranial hemorrhage within 48 hours. Results Among 1680 patients randomized (median age, 69 years; 727 female [43.3%]), 1673 (99.6%) completed the trial. The median 90-day modified Rankin Scale score was 3 (IQR, 1-5) in the methylprednisolone group vs 3 (IQR, 1-6) in the placebo group (adjusted generalized odds ratio for a lower level of disability, 1.10 [95% CI, 0.96-1.25]; P = .17). In the methylprednisolone group, there was a lower mortality rate (23.2% vs 28.5%; adjusted risk ratio, 0.84 [95% CI, 0.71-0.98]; P = .03) and a lower rate of symptomatic intracranial hemorrhage (8.6% vs 11.7%; adjusted risk ratio, 0.74 [95% CI, 0.55-0.99]; P = .04) compared with placebo. Conclusions and Relevance Among patients with acute ischemic stroke due to LVO undergoing endovascular thrombectomy, adjunctive methylprednisolone added to endovascular thrombectomy did not significantly improve the degree of overall disability.Trial RegistrationChiCTR.org.cn Identifier: ChiCTR210005172

    Comprehensive Forecast of Urban Water-Energy Demand Based on a Neural Network Model

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    Water-energy nexus has been a popular topic of rese arch in recent years. The relationships between the demand for water resources and energy are intense and closely connected in urban areas. The primary, secondary, and tertiary industry gross domestic product (GDP), the total population, the urban population, annual precipitation, agricultural and industrial water consumption, tap water supply, the total discharge of industrial wastewater, the daily sewage treatment capacity, total and domestic electricity consumption, and the consumption of coal in industrial enterprises above the designed size were chosen as input indicators. A feedforward artificial neural network model (ANN) based on a back-propagation algorithm with two hidden layers was constructed to combine urban water resources with energy demand. This model used historical data from 1991 to 2016 from Wuxi City, eastern China. Furthermore, a multiple linear regression model (MLR) was introduced for comparison with the ANN. The results show the following: (a) The mean relative error values of the forecast and historical urban water-energy demands are 1.58 % and 2.71%, respectively; (b) The predicted water-energy demand value for 2020 is 4.843 billion cubic meters and 47.561 million tons of standard coal equivalent; (c) The predicted water-energy demand value in the year 2030 is 5.887 billion cubic meters and 60.355 million tons of standard coal equivalent; (d) Compared with the MLR, the ANN performed better in fitting training data, which achieved a more satisfactory accuracy and may provide a reference for urban water-energy supply planning decisions

    PAK1-Dependent Regulation of Microtubule Organization and Spindle Migration Is Essential for the Metaphase I–Metaphase II Transition in Porcine Oocytes

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    P21-activated kinase 1 (PAK1) is a critical downstream target that mediates the effect of small Rho GTPase on the regulation of cytoskeletal kinetics, cell proliferation, and cell migration. PAK1 has been identified as a crucial regulator of spindle assembly during the first meiotic division; however, its roles during the metaphase I (MI) to metaphase II (MII) transition in oocytes remain unclear. In the present study, the potential function of PAK1 in regulating microtubule organization and spindle positioning during the MI–MII transition was addressed in porcine oocytes. The results showed that activated PAK1 was co-localized with α-tubulin, and its expression was increased from the MI to MII stage (p p p p < 0.001). Nevertheless, these adverse effects of IPA-3 on oocytes were reversed when the disulfide bond between PAK1 and IPA-3 was reduced by dithiothreitol (DTT). Co-immunoprecipitation revealed that PAK1 could recruit activated Aurora A and transform acidic coiled-coil 3 (TACC3) to regulate spindle assembly and interact with LIM kinase 1 (LIMK1) to facilitate actin filament-mediated spindle migration. Together, PAK1 is essential for microtubule organization and spindle migration during the MI–MII transition in porcine oocytes, which is associated with the activity of p-Aurora A, p-TACC3 and p-LIMK1

    Experimental Investigation of Coherent Vortex Structures in a Backward-Facing Step Flow

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    Coherent vortex structures (CVS) are discovered for more than half a century, and they are believed to play a significant role in turbulence especially for separated flows. An experimental study is conducted for a pressured backward-facing step flow with Reynolds number (Reh) being 4400 and 9000. A synchronized particle image velocimetry (PIV) system is developed for measurement of a wider range of velocity fields with high resolution. The CVS are proved to exist in the separation-reattachment process. For their temporal evolution, a life cycle is proposed that vortices form in the free shear layer, develop with pairings and divisions and finally shed at the reattachment zone, and sometimes new vortical structures are restructured with recovery of flow pattern. The CVS favor the free shear layer with frequent pairings and divisions particularly at the developing stage around x/h = 2~5 (x: distance from the step in flow direction, h: step height), which may contribute to the high turbulent intensity and shear stress there. A critical distance is believed to exist among CVS, which affects their amalgamation (pairing) and division events. Statistics show that the CVS are well organized in spatial distribution and show specific local features with the flow structures distinguished. The streamwise and vertical diameters (Dx and Dy) and width to height ratio (Dx/Dy) all obey to the lognormal distribution. With increase of Reh from 4400 to 9000, Dx decreases and Dy increases, but the mean diameter (D=0.5 Ă— (Dx + Dy)) keeps around (0.28~0.29) h. As the increase of Reh, the vortical shape change toward a uniform condition, which may be contributed by enhancement of the shear intensity
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