569 research outputs found

    Noise Radiation by Instability Waves in Coaxial Jets

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    In this paper predictions are made for the noise radiation from supersonic coaxial jets. The noise in the downstream arc of a supersonic jet is dominated by highly directional radiation from the supersonically convecting large scale structures in the jet mixing layer. Since the mean flow is not described easily in terms of simple analytic functions, a numerical prediction is made for its development. The compressible Reynolds-averaged boundary layer equations in cylindrical polar coordinates are solved. A mixing length turbulence model is used. Empirical correlations are developed the effects of velocity and temperature ratio and Mach number. Both normal and inverted velocity profiles are considered. Comparisons with measurements for both single and coaxial jets show good agreement. The large scale structures are modeled as instability waves. The noise radiation generated by the instability waves is determined by a matching between the inner instability wave solution and the outer acoustic solution. Predictions are made for the differences between the noise radiated by coaxial jets with different operating conditions and a single equivalent jet with the same exit area, thrust, and mass-flow

    Supersonic coaxial jet noise predictions

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    Predictions are made for the noise radiation from supersonic, coaxial jets. These predictions are based on the assumption that the noise radiation in the downstream direction of supersonic jets is dominated by sound generated by instability waves with supersonic phase velocities relative to ambient. Since the analysis requires a known mean flow and the coaxial jet mean flow is not described easily in terms of analytical functions, a numerical prediction is made for its development. The compressible, Reynolds averaged, boundary layer equations are solved with a modified mixing length turbulence model. The model has been calibrated to account for compressibility and temperature effects on the rate of mixing. Both normal and inverted velocity profile jets are considered. Predictions are made for the differences between the noise radiated by coaxial jets with difference operating conditions and a single reference jet with the same thrust, mass flow, and exit area. The effects of area ratio changes and simulated enhanced mixing on noise radiation are also considered

    Supersonic Jet Noise Reductions Predicted with Increased Jet Spreading Rate

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    In this paper, predictions are made of noise radiation from single, supersonic, axisymmetric jets. We examine the effects of changes in operating conditions and the effects of simulated enhanced mixing that would increase the spreading rate of the jet shear layer on radiated noise levels. The radiated noise in the downstream direction is dominated by mixing noise and it is well described by the instability wave noise radiation analysis. A numerical prediction scheme is used for the mean flow providing an efficient method to obtain the mean flow development for various operating conditions and to simulate the enhanced mixing. Using far field radiated noise measurements as a reference, the calculations predict that enhanced jet spreading results in a reduction of radiated noise

    Noise from Supersonic Coaxial Jets

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    The instability wave noise generation model is used to study the instability waves in the two shear layers of an inverted velocity profile, supersonic, coaxial jet and the noise radiated from the dominant wave. The inverted velocity profile jet has a high speed outer stream surrounding a low speed inner stream and the outer shear layer is always larger than the inner shear layer. The jet mean flows are calculated numerically. The operating conditions are chosen to exemplify the effect of the coaxial jet outer shear layer initial spreading rates. Calculations are made for the stability characteristics in the coaxial jet shear layers and the noise radiated from the instability waves for different operating conditions with the same total thrust, mass flow and exit area as a single reference jet. Results for inverted velocity profile jets indicate that relative maximum instability wave amplitudes and far field peak noise levels can be reduced from that of the reference jet by having higher spreading rates for the outer shear layer, low velocity ratios, and outer streams hotter than the inner stream

    Single wall carbon nanotubes enter cells by endocytosis and not membrane penetration

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    <p>Abstract</p> <p>Background</p> <p>Carbon nanotubes are increasingly being tested for use in cellular applications. Determining the mode of entry is essential to control and regulate specific interactions with cells, to understand toxicological effects of nanotubes, and to develop nanotube-based cellular technologies. We investigated cellular uptake of Pluronic copolymer-stabilized, purified ~145 nm long single wall carbon nanotubes (SWCNTs) through a series of complementary cellular, cell-mimetic, and in vitro model membrane experiments.</p> <p>Results</p> <p>SWCNTs localized within fluorescently labeled endosomes, and confocal Raman spectroscopy showed a dramatic reduction in SWCNT uptake into cells at 4°C compared with 37°C. These data suggest energy-dependent endocytosis, as shown previously. We also examined the possibility for non-specific physical penetration of SWCNTs through the plasma membrane. Electrochemical impedance spectroscopy and Langmuir monolayer film balance measurements showed that Pluronic-stabilized SWCNTs associated with membranes but did not possess sufficient insertion energy to penetrate through the membrane. SWCNTs associated with vesicles made from plasma membranes but did not rupture the vesicles.</p> <p>Conclusions</p> <p>These measurements, combined, demonstrate that Pluronic-stabilized SWCNTs only enter cells via energy-dependent endocytosis, and association of SWCNTs to membrane likely increases uptake.</p

    Single wall carbon nanotubes enter cells by endocytosis and not membrane penetration

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    <p>Abstract</p> <p>Background</p> <p>Carbon nanotubes are increasingly being tested for use in cellular applications. Determining the mode of entry is essential to control and regulate specific interactions with cells, to understand toxicological effects of nanotubes, and to develop nanotube-based cellular technologies. We investigated cellular uptake of Pluronic copolymer-stabilized, purified ~145 nm long single wall carbon nanotubes (SWCNTs) through a series of complementary cellular, cell-mimetic, and in vitro model membrane experiments.</p> <p>Results</p> <p>SWCNTs localized within fluorescently labeled endosomes, and confocal Raman spectroscopy showed a dramatic reduction in SWCNT uptake into cells at 4°C compared with 37°C. These data suggest energy-dependent endocytosis, as shown previously. We also examined the possibility for non-specific physical penetration of SWCNTs through the plasma membrane. Electrochemical impedance spectroscopy and Langmuir monolayer film balance measurements showed that Pluronic-stabilized SWCNTs associated with membranes but did not possess sufficient insertion energy to penetrate through the membrane. SWCNTs associated with vesicles made from plasma membranes but did not rupture the vesicles.</p> <p>Conclusions</p> <p>These measurements, combined, demonstrate that Pluronic-stabilized SWCNTs only enter cells via energy-dependent endocytosis, and association of SWCNTs to membrane likely increases uptake.</p
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