ARGON PLASMA COAGULATION USE IN PALLIATIVE TREATMENT OF TYPICAL-ATYPICAL CARCINOID TUMORS

Bronchial carcinoid tumors constitute 1-2% of all primary lung tumors. The main treatment for lung carcinoid tumors is surgery but bronchoscopic endobronchial therapy is also a palliative option for poor surgical candidates. This study will discuss the outcomes of bronchoscopic endobronchial treatment for two cases. Case 1 has a typical carcinoid tumor in right upper lobe and has multiple comorbidities. Case 2 is a patient with metastatic atypical carcinoid tumor who was operated before. We used argon plasma coagulation technique in treatment of both cases

Early effects of low molecular weight heparin therapy with soft-mist inhaler for covid-19-induced hypoxemia: A phase iib trial

© 2021 by the authors. Licensee MDPI, Basel, Switzerland.In COVID-19-induced acute respiratory distress syndrome, the lungs are incapable of filling with sufficient air, leading to hypoxemia that results in high mortality among hospitalized patients. In clinical trials, low-molecular-weight heparin was administered via a specially designed soft-mist inhaler device in an investigator initiated, single-center, open-label, phase-IIb clinical trial. Patients with evidently worse clinical presentations were classed as the “Device Group”; 40 patients were given low-molecular-weight heparin via a soft mist inhaler at a dose of 4000 IU per administration, twice a day. The Control Group, also made up of 40 patients, received the standard therapy. The predetermined severity of hypoxemia and the peripheral oxygen saturation of patients were measured on the 1st and 10th days of treatment. The improvement was particularly striking in cases of severe hypoxemia. In the 10-day treatment, low-molecular-weight heparin was shown to significantly improve breathing capability when delivered via a soft-mist inhaler