Type-2 diabetes mellitus diagnosis from time series clinical data using deep learning models.

Clinical data is usually observed and recorded at irregular intervals and includes: evaluations, treatments, vital sign and lab test results. These provide an invaluable source of information to help diagnose and understand medical conditions. In this work, we introduce the largest patient records dataset in diabetes research: King Abdullah International Research Centre Diabetes (KAIMRCD) which includes over 14k patient data. KAIMRCD contains detailed information about the patient’s visit and have been labelled against T2DM by clinicians. The data is processed as time series and then investigated using temporal predictive Deep Learning models with the goal of diagnosing Type 2 Diabetes Mellitus (T2DM). Long Short-Term Memory (LSTM) and Gated-Recurrent Unit (GRU) are trained on KAIMRCD and are demonstrated here to outperform classical machine learning approaches in the literature with over 97% accuracy

Collaborative Denoising Autoencoder for High Glycated Haemoglobin Prediction

A pioneering study is presented demonstrating that the presence of high glycated haemoglobin (HbA1c) levels in a patient’s blood can be reliably predicted from routinely collected clinical data. This paves the way for performing early detection of Type-2 Diabetes Mellitus (T2DM). This will save healthcare providers a major cost associated with the administration and assessment of clinical tests for HbA1c. A novel collaborative denoising autoencoder framework is used to address this challenge. The framework builds an independent denoising autoencoder model for the high and low HbA1c level, which extracts feature representations in the latent space. A baseline model using just three features: patient age together with triglycerides and glucose level achieves 76% F1-score with an SVM classifier. The collaborative denoising autoencoder uses 78 features and can predict HbA1c level with 81% F1-score

Type-2 Diabetes Mellitus Diagnosis from Time Series Clinical Data using Deep Learning Models

Clinical data is usually observed and recorded at irregular intervals and includes: evaluations, treatments, vital sign and lab test results. These provide an invaluable source of information to help diagnose and understand medical conditions. In this work, we introduce the largest patient records dataset in diabetes research: King Abdullah International Research Centre Diabetes (KAIMRCD) which includes over 14k patient data. KAIMRCD contains detailed information about the patient’s visit and have been labelled against T2DM by clinicians. The data is processed as time series and then investigated using temporal predictive Deep Learning models with the goal of diagnosing Type 2 Diabetes Mellitus (T2DM). Long Short-Term Memory (LSTM) and Gated-Recurrent Unit (GRU) are trained on KAIMRCD and are demonstrated here to outperform classical machine learning approaches in the literature with over 97% accuracy