Patient-reported change of sensibility and pain after parotid and labial gland biopsy applied for primary Sjogren's syndrome diagnostics: One-year follow-up study

Objective. To assess how patients perceived pain and change of sensibility of the biopsied area after having undergone parotid and labial gland biopsy as part of the diagnostic work-up of primary Sjogren's syndrome (pSS). Methods. Simultaneously, parotid and labial salivary gland biopsies were taken under local anesthesia. One week, 6 months and 12 months post-operatively, each patient was sent a postal questionnaire to quantify the severity of pain and change of sensibility in the biopsied areas with a visual analogue scale (VAS; range 0-100). Results. 110 patients were included. The median age of patients was 54 years (IQR=47-65) and 92% were female. Changes in sensibility and pain in the biopsied area were significantly higher after a parotid gland biopsy than after a labial gland biopsy at one week and 6 months post-operatively, but rather minor in both areas. At 12 months post-operatively, the change in sensibility and pain level was negligible in most patients and comparable for both biopsied areas. The duration of the technique, outcome of the biopsy, exposure of nerve branches during the biopsy and bleeding during the biopsy did not affect the reported change of sensibility or pain in the biopsied area. ESSPRI was not related to pain level or change of sensibility at any time point (r0.05). Conclusion. Patient-reported post-operative change of sensibility and pain in the area of the parotid and labial gland biopsy are minor and comparable. Parotid and labial gland biopsies are diagnostic techniques well tolerated by patients suspected with pSS

Design, manufacturing and characterization of integrated inductors with magnetic layers for DC-DC converter

International audienc

DEVELOPMENT OF AN ELECTRICAL MODEL FOR INTEGRATED MAGNETIC INDUCTORS

International audienceNowadays, the current trend consists in the development of new technologies with the aim of reducing volume, weight as well as production cost. With the aim of decreasing occupied component area, it will be interesting to use magnetic materials to confine the fields. Therefore, our works concern the modelling and the characterization of magnetic planar inductors. The proposed model is detailed for inductors fabricated with one magnetic layer. The model can take into account, the capacitance between turns and the capacitance between the last turn and the ground plane, the magnetic permeability, the skin and proximity effects of the conductors according to the frequency. The structure of optimization developed to extract the parameters of the model will be presented. Results of extracted parameters are compared with the simulation parameters. A good correlation is observed on Y11 and Y12 parameters on all the broad band frequency