Du Mésolithique au Néolithique en Méditerranée occidentale: l’impact africain - MeNeMOIA

[EN] Between the 8th and 5th millennia BC, the human societies of the Western Mediterranean underwent several major changes. The first occurred during the 7th millennium with the appearance of the ‘Second Mesolithic’. It can be seen mainly in the material productions of these populations, in particular their stone tool industries, by a fundamental change in production, operating sequences and technical procedures. Deeper changes in the social organization of these societies are also perceptible, in particular through changes in rites and funeral practices. The precise origin of these changes escapes us at present, but they seem to occur initially in North Africa before spreading rapidly along the Mediterranean shores and reaching Western Europe. A second major upheaval took place a few centuries later, with the appearance of the Neolithic. In this extensive process, the southern shores of the Mediterranean should not be ignored. Recent data suggest that, during the 6th millennium before our era, human communities practicing hunting and gathering and having acquired ceramic technology, occupied parts of the Maghreb. Interactions with spheres of the Impresso / Cardial complex occurred in southern Italy and, at the other end, southern Spain. This seems to be indicated by some traits of the technical systems of the first Neolithic communities of Andalusia. These hypotheses should now be tested by close examination of timelines and technical systems which if confirmed may offer a possible alternative to the strictly European scenarios. The international program of research, MeNeMOIA, financed for 2016 and 2017, will attempt to estimate the importance of a North African impact on European societies of recent prehistory (Second Mesolithic, Early Neolithic), a scenario breaking with the traditional scenario which, since decolonization, has recognized in Europe only movements of east-west diffusion and completely ignored any that might indicate movement from the south northward (or from the north southward) on both shores of the western Mediterranean.[FR] Entre les viiie et ve millénaires avant notre ère, les sociétés humaines du Bassin occidental de la Méditerranée connaissent plusieurs évolutions majeures. La première d’entre elles se déroule durant le viie millénaire avec l’apparition du «Second Mésolithique». Elle se matérialise principalement dans les productions matérielles de ces populations, et notamment dans leurs industries lithiques par un bouleversement des modes de production, des séquences opératoires et des gestes techniques. Des évolutions plus profondes, dans l’organisation sociale même de ces sociétés, sont également sensibles, notamment au travers de l’évolution des rites et pratiques funéraires. L’origine précise de ces évolutions nous échappe encore actuellement, mais elles semblent se produire initialement en Afrique du Nord avant de diffuser ensuite le long des rivages méditerranéens de manière rapide, et gagner ensuite l’ensemble de l’Europe occidentale. Un second bouleversement majeur se déroule quelques siècles après le précédent, avec l’apparition du Néolithique. Dans ce vaste processus, les rives sud de la Méditerranée ne doivent pas être ignorées. De récentes données suggèrent en effet que, durant le vie millénaire avant notre ère, des communautés humaines pratiquant chasse et cueillette et ayant acquis la technologie céramique occupaient certaines parties du Maghreb. Des interactions avec les sphères du complexe Impresso / Cardial ont ainsi pu voir le jour dans le Sud italien et, à l’autre extrémité, dans le sud de l’Espagne. C’est d’ailleurs ce que semblent montrer certains caractères des systèmes techniques des premières communautés néolithiques d’Andalousie. Ces hypothèses qu’il faut désormais confirmer par la confrontation étroite des chronologies et des systèmes techniques offrent donc une alternative possible aux scénarios classiques strictement européens. Le programme international de recherche MeNeMOIA, financé par l’IDEX toulousain pour 2016 et 2017, va donc s’attacher à évaluer l’importance des impacts nord-africains sur les sociétés européennes de la Préhistoire récente (Second Mésolithique, Néolithique ancien), scénario rompant avec les schémas traditionnels qui, depuis la décolonisation, se cantonnent à ne reconnaitre en Europe que des mouvements de diffusion est-ouest et ignorent complètement ceux allant du sud vers le nord (ou du nord vers le sud) de part et d’autre du Bassin occidental de la Méditerranée.Peer Reviewe

Objectivation des lesions traumatiques anciennes: evaluation clinique

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Electrophysiological assessment of the effect of intrathecal baclofen in spastic children

Objectives: To evaluate the effect of intrathecal baclofen in a group of spastic children using electrophysiological procedures described in adults. Methods: Six children (aged 1-14 years) with severe spasticity of various aetiologies underwent transcranial magnetic stimulation, H reflex and flexor reflex studies before and after intrathecal injection of baclofen. Ashworth scale was used for clinical evaluation of spasticity. Results: Motor evoked potentials, present in two patients before baclofen, were preserved after injection. Before baclofen, H reflex was present in 5 patients (Hmax/Mmax from 0.23 to 0.84) and absent in one who had infantile neuroaxonal dystrophy. After baclofen, it was absent in 4 patients and markedly reduced in one. Surface of flexor reflex significantly decreased after baclofen (P = 0.01), while threshold significantly increased (P = 0.003). Conclusions: In spastic children, the action of baclofen on spinal pathways may be quantified by the same electrophysiological procedures as in adults. This approach may contribute to select optimal dosage. © 2002 Elsevier Science Ireland Ltd. All rights reserved.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Spasticité: Physiopathologie et implications thérapeutiques

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Neuroanatomie fonctionnelle de la parole: Définition et classification des dysarthries

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La plasticité cérébrale: Avantage ou handicap surajouté

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Prise en charge d’une migraine

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Is selective dorsal rhizotomy a well-founded treatment for spasticity?

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Transcranial magnetic stimulation: A path from pyramidal to extrapyramidal syndrome ?

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Electrophysiological assessment of the effect of intrathecal baclofen in dystonic children.

OBJECTIVE: To evaluate the effect of intrathecal baclofen in a group of dystonic children using electrophysiological procedures previously validated in spastic children. METHODS: Seven children (aged 2-16 years) with dystonia of various aetiologies (dyskinetic cerebral palsy, pantothenate kinase-associated neurodegeneration and Aicardi-Goutières syndrome) underwent transcranial magnetic stimulation, H-reflex and flexor reflex studies before and after intrathecal injection of baclofen. The Barry-Albright Dystonia Scale (BADS) was used for clinical evaluation of dystonia. RESULTS: Motor-evoked potentials, present in 2 of 5 patients before baclofen, were preserved after injection. Before baclofen, H reflex was present in 6 of 7 patients (mean H(max)/M(max:) 0.45+/-0.21). It was markedly reduced after the injection (mean H(max)/M(max:) 0.09+/-0.11) (P<0.001). Area of flexor reflex significantly decreased after baclofen (P=0.047), while threshold significantly increased (P=0.01). No significant clinical improvement of the BADS scores was observed (P=0.058). CONCLUSIONS: These electrophysiological procedures, previously demonstrated to quantify the action of intrathecal baclofen in spastic adults and children, also appear sensitive in dystonic children. The electrophysiological changes are consistent with primarily spinal sites of action of baclofen. They appear more sensitive than clinical evaluation.Clinical TrialJournal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe