5 research outputs found
Intermolecular Aryl C-H amination through sequential iron and copper catalysis
A mild, efficient and regioselective method for paraâamination of activated arenes has been developed through a combination of iron and copper catalysis. A diverse range of products were obtained from an operationally simple oneâpot, twoâstep procedure involving bromination of the aryl substrate with the powerful Lewis acid iron(III) triflimide, followed by a copper(I)âcatalysed Nâarylation reaction. This twoâstep dehydrogenative process for the regioselective coupling of aromatic CâH bonds with nonâactivated amines was applicable to anisoleâ, phenolâ, anilineâ and acetanilideâtype aryl compounds. Importantly, the arene substrates were used as the limiting reagent and required no protectingâgroup manipulations during the transformation
Molecular memory with downstream logic processing exemplified by switchable and self-indicating guest capture and release
While many processes in biological cells can be understood in terms of molecular logic gates that process information sequentially and combinationally, the design and construction of such devices in the laboratory are unknown. Here the authors achieve this by the reversibly-controlled capture and release of guest molecules from host containers