8 research outputs found
Effects of an antisense napin gene on seed storage compounds in transgenic Brassica napus seeds
Heterogeneity in prey distribution allows for higher food intake in planktivorous fish, particularly when hot
Estimating Fish Exploitation and Aquatic Habitat Loss across Diffuse Inland Recreational Fisheries
Phytoplankton Spatial Variability in the River-Dominated Estuary, Apalachicola Bay, Florida
Hypertrophic Scarring and Keloids: Pathomechanisms and Current and Emerging Treatment Strategies
Excessive scars form as a result of aberrations of physiologic wound healing and may arise following any insult to the deep dermis. By causing pain, pruritus and contractures, excessive scarring significantly affects the patient’s quality of life, both physically and psychologically. Multiple studies on hypertrophic scar and keloid formation have been conducted for decades and have led to a plethora of therapeutic strategies to prevent or attenuate excessive scar formation. However, most therapeutic approaches remain clinically unsatisfactory, most likely owing to poor understanding of the complex mechanisms underlying the processes of scarring and wound contraction. In this review we summarize the current understanding of the pathophysiology underlying keloid and hypertrophic scar formation and discuss established treatments and novel therapeutic strategies