Efficacy and safety of brivudine for the treatment of herpes zoster: a systematic review and meta-analysis

Background and objective Brivudine has been used in herpes zoster (HZ) treatment for years, but the safety and efficacy of brivudine are inconclusive. Here we perform a meta-analysis to assess the efficacy, safety, incidence of postherpetic neuralgia of brivudine.Methods Data of randomized controlled Trials (RCTS) were obtained from the databases of both English (PubMed, Embase, and Cochrane Library) and Chinese (China National Knowledge Infrastructure, China Science Journal Database, and WanFang Database) literatures from inception to 12 September 2022. Meta-analyses of efficacy and safety of Brivudine for the treatment of herpes zoster for RCTS were conducted.Results The analyses included seven RCTS (2095 patients in experimental group and 2076 patients in control group) in the treatment of HZ with brivudine. It suggested that the brivudine group was superior to the control group in terms of efficacy (p = .0002) and incidence of postherpetic neuralgia (p = .04). But the incidence of adverse reactions has no significant difference between the brivudine and the control groups (p = .22). In addition, subgroup analysis of adverse events also showed that brivudine was about the same safety as other modalities in the treatment of HZ (p > .05).Conclusions Brivudine is effective for HZ. However, the evidence on the safety of brivudine is insufficient

Assessment of important soil properties related to Chinese Soil Taxonomy based on vis–NIR reflectance spectroscopy

Assessment of important soil properties related to Chinese Soil Taxonomy based on vis–NIR reflectance spectroscop

天然气水合物物理化学性质和相平衡数据库系统的设计和开发

天然气水合物作为一种重要的潜在能源，一种导致全球气候变化的因素，一种地质灾害的诱发因素，已经引起了各领域科研工作者的广泛关注。因此，迫切需要建立一个天然气水合物信息系统，以便交流和共享各领域的研究成果。在本工作中，我们设计开发了关于天然气水合物基础性质的数据库系统。目前，本系统所收集的数据主要集中在与天然气水合物开采和应用技术相关的物理化学性质、晶体结构和相平衡数据。本系统不仅能够提供数据检索服务，还能够提供相平衡数据的网络计算功能。本文将对数据收集和数据库开发这两个方面进行讨论

天然气水合物物理化学性质和相平衡数据库系统的设计和开发

天然气水合物作为一种重要的潜在能源，一种导致全球气候变化的因素，一种地质灾害的诱发因素，已经引起了各领域科研工作者的广泛关注。因此，迫切需要建立一个天然气水合物信息系统，以便交流和共享各领域的研究成果。在本工作中，我们设计开发了关于天然气水合物基础性质的数据库系统。目前，本系统所收集的数据主要集中在与天然气水合物开采和应用技术相关的物理化学性质、晶体结构和相平衡数据。本系统不仅能够提供数据检索服务，还能够提供相平衡数据的网络计算功能。本文将对数据收集和数据库开发这两个方面进行讨论

designanddevelopmentofdatabasesystemonthephysicalpropertiesandphaseequilibriaofgashydrates

天然气水合物作为一种重要的潜在能源，一种导致全球气候变化的因素，一种地质灾害的诱发因素，已经引起了各领域科研工作者的广泛关注。因此，迫切需要建立一个天然气水合物信息系统，以便交流和共享各领域的研究成果。在本工作中，我们设计开发了关于天然气水合物基础性质的数据库系统。目前，本系统所收集的数据主要集中在与天然气水合物开采和应用技术相关的物理化学性质、晶体结构和相平衡数据。本系统不仅能够提供数据检索服务，还能够提供相平衡数据的网络计算功能。本文将对数据收集和数据库开发这两个方面进行讨论