561 research outputs found

    Os movimentos do narrador e a matéria rural: notas sobre "Vidas secas"

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    O artigo analisa o narrador e as suas relações com a matéria rural no romance Vida secas, de Graciliano Ramos. O objetivo é caracterizar os movimentos contraditórios do narrador que se configuram no instante mesmo de ele se aproximar, captar e enunciar a experiência de vida de Fabiano, da sua família e da cachorra Baleia. Esses movimentos contraditórios são vistos como formalização da linguagem transpassada pelos impasses e conflitos de classe derivados do estatuto social narrador e sua relação com a matéria rural

    The BioGRID Interaction Database: 2011 update

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    The Biological General Repository for Interaction Datasets (BioGRID) is a public database that archives and disseminates genetic and protein interaction data from model organisms and humans (http://www.thebiogrid.org). BioGRID currently holds 347 966 interactions (170 162 genetic, 177 804 protein) curated from both high-throughput data sets and individual focused studies, as derived from over 23 000 publications in the primary literature. Complete coverage of the entire literature is maintained for budding yeast (Saccharomyces cerevisiae), fission yeast (Schizosaccharomyces pombe) and thale cress (Arabidopsis thaliana), and efforts to expand curation across multiple metazoan species are underway. The BioGRID houses 48 831 human protein interactions that have been curated from 10 247 publications. Current curation drives are focused on particular areas of biology to enable insights into conserved networks and pathways that are relevant to human health. The BioGRID 3.0 web interface contains new search and display features that enable rapid queries across multiple data types and sources. An automated Interaction Management System (IMS) is used to prioritize, coordinate and track curation across international sites and projects. BioGRID provides interaction data to several model organism databases, resources such as Entrez-Gene and other interaction meta-databases. The entire BioGRID 3.0 data collection may be downloaded in multiple file formats, including PSI MI XML. Source code for BioGRID 3.0 is freely available without any restrictions

    A simple radionuclide-driven single-ion source

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    We describe a source capable of producing single barium ions through nuclear recoils in radioactive decay. The source is fabricated by electroplating 148Gd onto a silicon {\alpha}-particle detector and vapor depositing a layer of BaF2 over it. 144Sm recoils from the alpha decay of 148Gd are used to dislodge Ba+ ions from the BaF2 layer and emit them in the surrounding environment. The simultaneous detection of an {\alpha} particle in the substrate detector allows for tagging of the nuclear decay and of the Ba+ emission. The source is simple, durable, and can be manipulated and used in different environments. We discuss the fabrication process, which can be easily adapted to emit most other chemical species, and the performance of the source

    Gene Ontology annotations at SGD: new data sources and annotation methods

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    The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org/) collects and organizes biological information about the chromosomal features and gene products of the budding yeast Saccharomyces cerevisiae. Although published data from traditional experimental methods are the primary sources of evidence supporting Gene Ontology (GO) annotations for a gene product, high-throughput experiments and computational predictions can also provide valuable insights in the absence of an extensive body of literature. Therefore, GO annotations available at SGD now include high-throughput data as well as computational predictions provided by the GO Annotation Project (GOA UniProt; http://www.ebi.ac.uk/GOA/). Because the annotation method used to assign GO annotations varies by data source, GO resources at SGD have been modified to distinguish data sources and annotation methods. In addition to providing information for genes that have not been experimentally characterized, GO annotations from independent sources can be compared to those made by SGD to help keep the literature-based GO annotations current

    Search for Neutrinoless Double-Beta Decay in 136^{136}Xe with EXO-200

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    We report on a search for neutrinoless double-beta decay of 136^{136}Xe with EXO-200. No signal is observed for an exposure of 32.5 kg-yr, with a background of ~1.5 x 10^{-3} /(kg yr keV) in the ±1σ\pm 1\sigma region of interest. This sets a lower limit on the half-life of the neutrinoless double-beta decay T1/20νββT_{1/2}^{0\nu\beta\beta}(136^{136}Xe) > 1.6 x 1025^{25} yr (90% CL), corresponding to effective Majorana masses of less than 140-380 meV, depending on the matrix element calculation
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