Creative Engagements and Cross-Disciplinary Approaches to the Study of Business

published_or_final_versio

Optimization of facade design based on the impact of interior obstructions to daylighting

Overcrowding in the perimeter zone is an inevitable issue in residential rooms with limited space. Obstructions, such as furniture and household items, may block the existing windows, and therefore affect interior daylight conditions. A facade design approach is needed that simultaneously takes into account daylighting and the volume of usable space for obstructions in the perimeter zone of such rooms. This study simulates daylight distributions in a typical small residential room with obstructions in front of windows. The simulation consists of two parts. First, the effects on horizontal illuminances caused by different positions and shapes of obstructions are examined under an overcast sky. Second, the maximum usable space volumes for obstructions of 51 optimized facade configurations are calculated in terms of four window-to-wall ratios (WWRs). The results of this study show that optimizing the forms of facade design can increase the usable interior space volume and meet the daylighting requirements of Chinese standards for small residential rooms. Additionally, by using the optimized facade forms, a facade with a WWR value of 50% provides the maximum usable space for obstructions. Based on the above results, this paper presents two matrices that can help architects in selecting the appropriate fenestration methods and confirming the size of usable space and allocation for residents

The role of deoxycytidine-metabolizing enzymes in the cytotoxicity induced by 3′-amino-2′,3′-dideoxycytidine and cytosine arabinoside

The cellular metabolism of 3′-amino-2′,3′-dideoxycytidine (3′-NH 2 -dCyd), a cytotoxic agent previously reported to be a poor substrate for purified Cyd/dCyd deaminase (dCydD), was compared with that of cytosine arabinoside (ara-C) in cells that displayed dCydD activity (HeLa) and in cells that did not (L1210). Growth inhibition induced by 3′-NH 2 -dCyd was dependent on the levels of anabolic enzymes, particularly dCyd kinase (dCydK), whereas cytotoxicity induced by ara-C was dependent on the expression of both anabolic and catabolic enzyme activities. Competition kinetics using purified enzyme revealed that the binding affinity of ara-C to dCydK was 5-fold that of the amino analog. However, this binding advantage is apparently offset in cells that contain high levels of dCydD, since the K i values for this enzyme were 0.2 and 23 mm for ara-C and 3′-NH 2 -dCyd, respectively. This was reflected in the decrease in analog sensitivity observed between the two cell lines, whereby the concentrations of ara-C and 3′-NH 2 -dCyd required to inhibit growth by 50% were 200 and 7 times higher, respectively, in the dCydD-containing HeLa cells as compared with the dCydD-deficient L1210 cells. The metabolic stability and cytotoxicity of 3′-NH 2 -dCyd was independent of cell number. An unexpected finding was the extent to which the effectiveness of ara-C could be mitigated by the number of dCydD-containing cells. A completely cytotoxic concentration of ara-C was rendered nontoxic by a 10-fold increase in cell number. This observation was supported by an increase in I-β- d -arabinofuranosyluracil (ara-U) formation, a decrease in ara-C 5′-triphosphate (ara-CTP) accumulation, and a rise in cell viability with increasing cell number. These findings indicate that unlike ara-C, the effectiveness of 3′-NH 2 -dCyd is independent of the level of deaminase, which suggests its possible utility in situations in which high levels of deaminase are manifest.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46922/1/280_2004_Article_BF00686406.pd

A Case of Banal Nationalism: TV drama and Identity in Hong Kong

Session 3: Formation of Hong Kong Identity and Pop Cultur

Biographical experience, desires, and interests: a case study of individual Hong Kong fans of Japanese Boy Love Comics

Oral Presentation 297 - Visual Turn and Popular Culture: Anime, Manga and Comics in Japan, Korea and China: no. 297.1Congress Theme: Facing an Unequal World: Challenges for Global SociologyThis paper is an ethnographic attempt to understand the relationship between individual Hong Kong fans of Japanese Boy Love (BL) comics and the general image of male characters in BL through the fans’ derivative creation of BL. The key concept here is the desire. We show that while Hong Kong fans of Japanese BL comics share a collective meaning of the general image of male characters in BL comics, each of them tends to maintain a unique interest in it. We further argue that the unique interest in the general image of male characters in BL comics is closely related to the biographical experience of each individual Hong Kong fan. The biographical experience itself is a product of many social factors, among which family is the most important one. Following Sangren (2000), we argue that in order to understand how biographical experience shapes unique interest of each individual fan, we should understand how family as a social institution underlies the desire of individual fans toward BL comics in general and the general image of male character in BL comics in particular. The desires instituted by family in turn will be shown to motivate the unique behavior of individual fans toward BL comics. Through this ethnographic attempt, we shall try to transcend the classic dichotomy of individual and society, sociology and psychology, and culture and personality lingering in social sciences in general and sociology in particular

公共財の知の空間としての大学－学術資本主義の諸問題

Organised by: 日本学術会議（第一部国際協力分科会）、国際社会科学団体連盟（OFSSO）、成城大

Creative Potential of the Fan Culture in Hong Kong

由日本神大学主办, 北京大学文化产业研究院协办会议主题: 亚洲文化新浪潮与创意产业的新生