Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options

Mast cell activation disease comprises disorders characterized by accumulation of genetically altered mast cells and/or abnormal release of these cells' mediators, affecting functions in potentially every organ system, often without causing abnormalities in routine laboratory or radiologic testing. In most cases of mast cell activation disease, diagnosis is possible by relatively non-invasive investigation. Effective therapy often consists simply of antihistamines and mast cell membrane-stabilising compounds supplemented with medications targeted at specific symptoms and complications. Mast cell activation disease is now appreciated to likely be considerably prevalent and thus should be considered routinely in the differential diagnosis of patients with chronic multisystem polymorbidity or patients in whom a definitively diagnosed major illness does not well account for the entirety of the patient's presentation

Realistic low-latency mobile AR rendering

When designing a system for mobile augmented reality, problems to be tackled concern tracking, rendering performance, end-to-end latency, battery usage, and communication bandwidth of the mobile platform. We developed an integral solution covering all these aspects, while still being manageable from the application's point of view. In this paper we outline the global layout of our system, and discuss a demo application projecting a statue on the campus

Allergen Immunotherapy Adherence in the Real World: How Bad Is It and How Can It Be Improved?

adherence in allergic disease