High-throughput in-situ characterization and modelling of precipitation kinetics in compositionally graded alloys

The development of new engineering alloy chemistries is a time consuming and iterative process. A necessary step is characterization of the nano/microstructure to provide a link between the processing and properties of each alloy chemistry considered. One approach to accelerate the identification of optimal chemistries is to use samples containing a gradient in composition, ie. combinatorial samples, and to investigate many different chemistries at the same time. However, for engineering alloys, the final properties depend not only on chemistry but also on the path of microstructure development which necessitates characterization of microstructure evolution for each chemistry. In this contribution we demonstrate an approach that allows for the in-situ, nanoscale characterization of the precipitate structures in alloys, as a function of aging time, in combinatorial samples containing a composition gradient. The approach uses small angle x-ray scattering (SAXS) at a synchrotron beamline. The Cu-Co system is used for the proof-of-concept and the combinatorial samples prepared contain a gradient in Co from 0% to 2%. These samples are aged at temperatures between 450{\textdegree}C and 550{\textdegree}C and the precipitate structures (precipitate size, volume fraction and number density) all along the composition gradient are simultaneously monitored as a function of time. This large dataset is used to test the applicability and robustness of a conventional class model for precipitation that considers concurrent nucleation, growth and coarsening and the ability of the model to describe such a large dataset.Comment: Published in Acta Materiali

Vies moyennes de quelques niveaux du noyau 19F

Les énergies d'excitations et les vies moyennes de 9 niveaux du 19 F d'énergie inférieure à 6 MeV ont été déterminées à l'aide de la réaction 18O(d, nγ) 19F. De ces vies moyennes, mesurées à partir de la méthode du déplacement Doppler, ont été déduites certaines largeurs de transition M1 qui sont comparées aux prédictions de modèles en couches

Total knee arthroplasty for osteoarthritis secondary to extra-articular malunions

SummaryIntroductionPost-traumatic total knee arthroplasty for extra-articular malunion requires correction of the deformity, either through asymmetrical bone resection (possibly inducing ligaments imbalance) or osteotomy at the time of arthroplasty. We report the results of a continuous multicenter, retrospective series of 78 patients (18 implants with osteotomy) with a mean 4 years of follow-up. The hypothesis is that the selected procedure requires to be based on the deformity's location and severity.PatientsWith a mean age of 63 years (younger in the osteotomy group), 38 patients had femoral malunion, 36 had tibial malunion, and four had a combined malunion. There were 70 frontal deformities (48 varus and 22 valgus) and 10 rotational deformities, often diaphyseal, four of which more than 20°. Twelve patients had a history of infection; eight had frontal laxity greater than 10°, and 15 a limited range of motion in flexion. In 70 cases, semi- or nonconstrained implants were used, and in eight cases more constrained implants, including four hinge prostheses.ResultsWe observed two deep infections, one case of avulsion of the extensor mechanism, and two cases of aseptic loosening with femoral malunion and varus deformity. Two osteotomies resulted in nonunion, one with internal fixation devices mobilization requiring revision using extension rods. The function and pain scores were significantly improved. The mobility improvements were moderate but did not compromise the surgical procedure main objective. The preoperative hip-knee angle was corrected with both techniques. Only the function score gain was greater for the isolated arthroplasty procedures.Discussion and conclusionThe indications for arthroplasty alone were extended to 20° varus and 15° valgus, with no major residual laxity. Beyond 10°, hinge prosthesis should be available. Associated osteotomy can correct rotational deformities that cannot be compensated with bone cuts. In deformities that are close to the joint, osteotomy facilitates implantation of moderately constrained prosthesis. This indication is based on CAT scan rotational deformities measurements because rotational deformities require an osteotomy, and/or the presence of extraligamentous deformity that cannot be reduced with collateral ligaments surgical release.Level of evidenceLevel 4. Non-controlled retrospective study

Produção de Forragem e Interceptação de Luz.

bitstream/item/28554/1/ClicNews-2010-3.pd

Estrutura da Pastagem e Produtividade de Forragem.

bitstream/item/28563/1/ClicNews-2010-5.pd

Área Foliar e Produtividade de Forragem.

bitstream/item/28405/1/ClicNews-2010-7.pd

An update on the human and animal enteric pathogen Clostridium perfringens

Clostridium perfringens, a rapid-growing pathogen known to secrete an arsenal of >20 virulent toxins, has been associated with intestinal diseases in both animals and humans throughout the past century. Recent advances in genomic analysis and experimental systems make it timely to re-visit this clinically and veterinary important pathogen. This Review will summarise our understanding of the genomics and virulence-linked factors, including antimicrobial potentials and secreted toxins of this gut pathogen, and then its up-to-date clinical epidemiology and biological role in the pathogenesis of several important human and animal-associated intestinal diseases, including pre-term necrotising enterocolitis. Finally, we highlight some of the important unresolved questions in relation to C. perfringens-mediated infections, and implications for future research directions

Women, ethnicity and nationalisms in Latin America

Gutierrez Chong, Natividad (ed. lit.) "Women, ethnicity and nationalisms in Latin America". Aldershot : Ashgate, 2007. 235 p. ISBN 978-075-464-925-0Nationalism is a multifaceted phenomenon that has recently become a focus of redefinition through new multidisciplinary and multi-method approaches. The complex links among gender, ethnicity and nationalism, neglected for a long time in academic research, are increasingly receiving coverage in the scholarly literature. The book "Women, Ethnicity and Nationalisms in Latin America”, edited by Natividad Gutiérrez Chong, systematically explores these links in the context of Latin America, with case studies covering Argentina, Ecuador, Bolivia and Mexico. Contributions are by leading Latin American scholars from diverse academic fields who share the aim of overcoming the limitations of the Eurocentric and androcentric framework that characterizes the main approaches to nationalism