Assessment of submicroscopic genetic lesions by single nucleotide polymorphism arrays in a child with acute myeloid leukemia and FLT3-internal tandem duplication

The same FLT3-internal tandem duplication (ITD) positive clone was detected at diagnosis and relapse, but not at birth, in a child with M1 acute myeloid leukemia. Single nucleotide polymorphism arrays demonstrated that chromosome 13 acquired uniparental disomy, in association with del(9q), represented a progressive event in the course of the disease, and it was responsible for the homozygous FLT3-ITD at relapse

Phase space quantum mechanics via frame quantization on finite groups

In this work, the version of Wigner transforms and Wigner functions on discrete systems are formulated. Using frame quantization, the star-product of phase space functions are also computed for a particular finite group. Specifically, the Wigner transform, Wigner function and star-product are computed for the dicyclic group Dien. Frames are the discrete version of coherent states. In the literature, quasiprobability distributions are essential in the study of the phase space representations of quantum mechanics, and are naturally associated to frame quantizations. For this work, the unitary irreducible representations of a finite group play an essential role in the construction

Cold Spraying of Armstrong Process Titanium Powder for Additive Manufacturing

International audienc

Monitoraggio di pesticidi clorurati in campioni di mangimi mediante GC/ECD tandem

Pubblicato on-line dalla SISVE

Perception on the effectiveness of simulation as a learning strategy in improving the decision making skills of nursing students Batches 2015 and 2016 of De La Salle Health Sciences Institute

A non-experimental descriptive type of research design was used in this study. A total of 123 respondents were included in the study and were chosen using non-probability purposive sampling. The research instrument used was patterned from Lasater’s (2006) Clinical Judgement Rubric. Data was analysed using frequency, percentage, mean, t-test, and f-test. Most of the respondents were 18-20 years old, females, on level IV and had participated on six (6) or more simulation activities. Simulation as a learning strategy was highly effective in improving decision making skills as perceived by nursing students batches 2015 and 2016 of De La Salle Health Sciences Institute. Age and gender affected the perception of nursing students batches 2015 and 2016 on the effectiveness of simulation as a learning strategy in improving decision making skills. On the other hand, year level and number of simulation participated did not affect the perception of nursing students batches 2015 and 2016 on the effectiveness of simulation as a learning strategy in improving the decision making skills

Manufacturing of aluminum coating on 3D-printed onyx with cold spray technology

Composite materials are widely used as main parts and structural components in different fields, especially for automotive and military applications. Although these materials supply different advantages comparing to the metals, their implementation in engineering applications is limited due to low electrical and thermal properties and low resistance to erosion. To enhance these above-mentioned properties, the metallization of composite materials by creating a thin metal film on their surface can be achieved. Among different coating deposition techniques, Cold Spray appears to be the most suitable one for the metallization of temperature-sensitive materials such as polymers and composites with a thermoplastic matrix. This process relies on kinetic energy for the formation of the coating rather than on thermal energy and consequent erosion and degradation of the polymer-based composite can be avoided. In the last years, a new method to produce composite materials, as known as Fused Filament Fabrication (FFF), has been developed for industrial applications. This technique consists of a 3D printing process that involves the thermal extrusion of thermoplastic polymer and fibers in the form of filaments from a heated mobile nozzle. The implementation of this new technique is leading to the manufacturing of customized composite materials for the cold spray application. In the presented experimental campaign, Onyx material is used as a substrate. This material is made of Nylon, a thermoplastic matrix, and chopped carbon fibers randomly dispersed in it. Aluminum powders were cold sprayed on the Onyx substrate with a low-pressure cold spray (LPCS) system. This study aims to investigate the possibility of the metalizing 3D-printed composite material by cold spray technology. For this purpose, optical and microscopical analyses are carried out. Based on the results, the feasibility of the process and the influence of the morphology of the substrate are discussed, and optimal spraying conditions are proposed

Fused filament fabrication of ONYX-based composites coated with aluminum powders: A preliminary analysis on feasibility and characterization

Polymer-based AM methods are the most mature additive technologies for their versatility and variety of products obtainable. The addition of fibre reinforcement can also confer to the manufactures produced good mechanical properties. Unfortunately, several applications are still precluded because polymers cannot guarantee appropriate electrical conductivity, erosion resistance and operating temperature. Aiming to overcome these issues, the metallization of the surfaces emerges as a possible solution. Unfortunately, thermoplastic polymers exhibit thermosensitive behaviour and run the risk of being damaged when traditional metallization techniques, which require the melting of metal powders which will act as a protective coating. For this reason, studies have focused on Cold Gas Dynamic Spray, an additive manufacturing technology, which exploits kinetic energy to favour the adhesion of metal particles rather than the increase in temperature. In this work, a first attempt is made to verify the feasibility of cold spray coatings on 3D printed composite substrates, produced by means of Fused Filament Fabrication (FFF) technique. FFF technology allows the deposition of two different types of filaments by using a double extruder. These composite fibres within 3D printed parts manage to give the object a resistance comparable to that of a metal part with lower production cost and a high degree of automation. These structures, made of ONYX, a Nylon matrix in which short carbon fibres are dispersed, and reinforced with long carbon fibres, are designed to better fit the CS deposition. Aluminium coatings have been produced and a characterization campaign has been carried on

Corrugated electrode/electrolyte iInterfaces in SOFC : theoretical and experimental development

International audienceThe present work proposes to explore how the presence of a periodic pattern at electrode/electrolyte interfaces of a SOFC could impact the electrochemical performances, from theoretical and experimental points of view. The model results demonstrate that a patterned interfaces along with an electrolyte having a thickness smaller than the dimensions of the pattern, lead to a strong increase of the exchange surface, hence to the exchange currents (up to 64%) with respect to flat interfaces. With the use of laboratory standard ceramic processes, this architecturation was experimented on YSZ-Ni self supported anodes on top of which a thin YSZ electrolyte was deposited. The first electrical tests for such a cell with a non-optimized thickness show an increase of the current density with respect to a cell with flat interfaces, from 130 to 300 mA cm-2 at 0.7 V, that is even higher than anticipated by the modeling