Measurement of abdominal muscle thickness using ultrasound: A reliability study on patients with chronic nonspecific low back pain

Background and purpose: The purpose of this study was to assess the Within-day and Between-days reliability of abdominal muscles size measurement in patients with chronic non-specific low back pain (LBP) using ultrasound (US). Materials and methods: In this study, 15 patients with chronic non-specific LBP (20-50 years old) were recruited. The reliability of the abdominal muscle size (External and Internal oblique, and Transversus abdominis) was assessed in a relaxed and contraction state by a real time US. Two images were taken on the same day with an hour interval to assess the within day reliability and the third image was taken a week later to determine the between- days reliability. Results: Within-day and between-days reliability of abdominal muscles thickness measurements using US in patients with nonspecific chronic LBP in both rest and contraction state found to be high, ICC = 0.90 for within and ICC=0.85 for between-days of Transversus abdominis muscle in rest state and ICC= 0.82 and 0.86 in contraction state, respectively. For Internal oblique muscle, ICC=0.90 (82) and ICC=0.88 (88) were found for within-day and between-days in rest and contraction state, respectively. Within-day and between-days reliability at rest of ICC=0.86 (79) and in contraction state of ICC=0.79 (75) were demonstrated for External Oblique muscle. Conclusion: Results of the present study suggest US as a reliable method to evaluate the thickness of the abdominal muscles which could be used as a reliable tool in the assessment of patients and also in evaluating the effect of different therapeutic interventions. © 2015, Mazandaran University of Medical Sciences. All rights reserved

The possible impact of sortilin in reducing HBsAg expression in chronic hepatitis B

Hepatitis B virus (HBV) infection is a major global health problem. Chronically infected people are at risk for progressive hepatic fibrosis and consequent cirrhosis. Hepatitis B surface antigen (HBsAg) level in serum is a complementary marker for intrahepatic HBV DNA and covalently closed circular DNA (cccDNA). Sortilin-1 (SORT1) has been reported to be involved in the post-Golgi vesicle trafficking of Apo lipoproteins degradation pathways. This study was designed to evaluate the hepatic and serum expression of HBsAg and its association with hepatic SORT1 gene expression in patients with chronic HBV. Thirty chronic hepatitis B patients with histological examination results were enrolled in this study. Liver biopsies were analyzed for hepatic HBsAg and SORT1 gene expression by immunohistochemistry and quantitative real time PCR (qRT-PCR), respectively. Twenty seven out of 30 (90%) liver biopsies had positive staining for HBsAg and showed a significant inverse association with hepatic SORT1 fold change gene expression (β=-0.5, P=0.042). There was significant association between HBV DNA levels and HBsAg expression in hepatocyte or serum titer of HBsAg (r=0.39, P=0.029; r=0.39, P=0.032 respectively). Serum ALT was also correlated with hepatic activity index (HAI) score (β=0.6, P=0.001). Inverse association between hepatic SORT1 gene expression and hepatic HBsAg expression indicates the possible role of sortilin in HBsAg particle formation. © 2016 Wiley Periodicals, Inc

A UHF 4th-order band-pass filter based on contour-mode PZT-on-silicon resonators

A UHF 4th-order band-pass filter (BPF) based on the subtraction of two 2nd-order contour-mode resonators with slightly different resonance frequencies is presented. The resonators consists of a 1 μm pulsed-laser deposited (PLD) lead zirconate titanate (PZT) thin-film on top of a 3 μm silicon (PZT-on-Si). The resonators are actuated in-phase and their outputs are subtracted. Utilizing this technique, the outputs of the resonators are added up constructively while the feed-through signals are eliminated. The BPF presented a bandwidth of approximately 28.6 MHz and more than 30 dB stopband rejection at around 700 MHz

Study of existing biological communities in Hormuzgan province waters (Persian Gulf) for installation of artificial reefs

To determine the suitable locations for installation of artificial reefs we studied Persian Gulf waters (Hormuzgan province) from December 2006 to March 2007 seasonally. The area was stratified to 10 transects and each transect was divided to three layers and used random sampling method. Habitats of fauna and flora including: Communities of corals, seaweeds, sea cucumbers and sea grasses, and sedimentation depth using SCUBA diving method were studied in each transect and layer. Sea grass communities existed in some places with below 10m depth of Bandar Mesan, Bandar Kang, Kish Island and Bandar Chirooyeh transects. Also, seaweed habitats were seen in Bandar Mesan and some areas in Bandar Lengeh and Kish Island in 10-20m depth transect. The study of coral and sea cucumber communities indicated presence of Acropora sp. habitats in Bahman jetty, Bandar Mesan and Bandar Bostaneh transects , and Porites sp. habitats in Hengam island transect, Holothuria sp. habitats in Bandar masen and Bandar Lengeh transects and Stichopus sp. habitat in Hengam Island transect. All these species were found in shallow waters bellow 10 meters depth and showed a patchy distribution. Sedimentation depth results showed a statistically significant difference between layer <10m in Bandar Salakh and the same layers in other transects, also between layer 10-20m and 20-30m in other transects. Based on the sedimentation depth and habitats studies, we recommend layer 10-20m in Bandar Lengeh area and Bandar Lengeh to Hendurabi Island area as suitable for artificial reefs installation

Gastrointestinal microflora of captured stellate sturgeon (Acipenser stellatus, Pallas, 1771) from Southeast Caspian Sea, Iran

Acipenser stellatus is one of the most invaluable species of Sturgeon fishes in the world. The purpose of this study was to identify the resident microbial community from the gastrointestinal tract (GIT) of Acipenser stellatus. One hundred and twenty three fungi were isolated from the GIT of 7 Acipenser stellatus samples including Aspergillus spp (45.5%), Trichoderma spp (8.9%) and Cladophialophora spp (8.1%). Among different Aspergillus isolates, A. niger was the predominant species. Although, fungi were predominantly isolated from stomach (36.6%), but with respect to frequency of fungal isolates there were no significant differences between stomach and other parts of GI. In general, the bacterial isolates recovered were mostly gram negative and related to Enterobacteriaceae family such as Aeromonas, Pseudomonas and Salmonella species. The most bacterial species were isolated from intestine and pre stomach region (88.2%). It is concluded that A. niger and Aeromonas species were predominant fugal and bacterial microbes isolated from understudy fish GIT, respectively

Regeneralized London free-energy for high-c T vortex lattices

Abstract The London free-energy is regeneralized by the Ginsburg-Landau free-energy density in the presence of both d and s order parameters. We have shown that the strength of the s-d coupling, , makes an important rule to determine the form of the lattice vortex. Appearance of the ratios of the coherence length to penetration depth in the higher order corrections of the free-energy density will truncate these corrections for even large values of

Giant segregation transition as origin of liquid metal embrittlement in the Fe-Zn system

A giant Zn segregation transition is revealed using CALPHAD-integrated density-based modelling of Zn segregation into Fe grain boundaries (GBs). The results show that above a threshold of only a few atomic percent Zn in the alloy, a substantial amount of up to 60 at.% Zn can segregate to the GB. We also found that the amount of segregation significantly increases with decreasing temperature, while the required Zn content in the alloy for triggering the segregation transition decreases. Direct evidence of this Zn segregation transition is obtained using high-resolution scanning transmission electron microscopy. We trace the origin of the segregation transition and its temperature dependence back to the low cohesive energy of Zn and a miscibility gap in Fe-Zn GB, arising from the magnetic ordering effect, which is demonstrated by ab initio calculations. We show that the massive Zn segregation resulting from the segregation transition greatly assists with liquid wetting and reduces the work of separation along the GB. These findings reveal the fundamental origin of GB weakening and therefore liquid metal embrittlement in the Fe-Zn system.Comment: Original work, Letter, 14 pages including supplementary material (SM), 8 figures (3 in SM), 2 tables in S

Pretreatment with Ultrasonication Reduces the Size of Azelaic Acid-Chitosan Nanoparticles Prepared by Electrospray

Nowadays, electrospray is becoming a favourable approach for preparing monodispersed nanoparticles. However, this approach is quite recent and requires further works to optimize control over physicochemical properties of its products. This study aimed to determine the possible effects of sonication as a pretreatment to reduce the size of azelaic acid-chitosan particle before using electrospray. The results showed that sonication treatment can produce submicron particles of azelaic acid-chitosan. By diluting the solution and increasing sonication time and amplitude, smaller particles were obtained with the smallest one at 516 nm, sized by dynamic light scattering. The pretreated solution was then electrosprayed to reduce the size of nanoparticles to 80 nm, indicating that sonication may play an important role in reducing the size of electrosprayed nanoparticles. The electrosprayed nanoparticles were nearly monodispersed and almost spherical in shape

Fairness of health financing before and after introduction of iranian health sector evolution plan: A case study

Introduction: Since out-of-pocket payments of household are a serious obstacle to the equitable utilization of health services, paying attention to the direct payment of households and, consequently, incidence of catastrophic health expenditures should always be considered in the planning and policy-making of health services. Iranian Health Sector Evolution Plan (HSEP) has been implemented since 2014, aiming at achieving universal coverage of health services and reducing the amount of out-of-pocket payments as a percentage of total health expenditures. Aim: To measure the fairness of health care financing and to identify incidence rate of catastrophic health expenditures and it�s most important determinants before and after implementing the HSEP among households in one province of Iran (Lorestan). Materials and Methods: The study population of present cross-sectional research was Lorestan households whose information was collected by a three-stage randomized cluster sampling method by the Statistics Center of Iran during 4/2012-3/2015. For data analysis, Logit�s regression model using Stata14 software was performed. Results: Based on the findings between 4/2012 and 3/2015, the incidence rate of Catastrophic Health Expenditure (CHE) reduced from 6.7 to 4.34 and Fairness Financial Contribution Index (FFCI) varied from 0.66 to 0.74 and percentage of poverty due to health expenditure varied from 1.96 to 0.28. The most important determinants of facing catastrophic health expenditure are economic status of households, location of households (urban or rural), and number of people over the age of 65 and under the age of 5 in the household, age and sex of household head and insurance status of households. The use of health care also showed a significant relationship with the incidence of catastrophic health expenditure. Conclusion: After implementing Iranian HSEP, the incidence of CHE and the percentage of poverty caused by health expenditure at the level of households were reduced to some degree, and fairness financial contribution index improved. The finding of this study will help health policymakers to identify factors increasing the likelihood of household exposure to catastrophic health expenditure, and based on these factors, to review and revise the programs implemented within the framework of Iranian HSEP and adopt appropriate policies to promote the protection of households against catastrophic health expenditure. © 2018, Journal of Clinical and Diagnostic Research. All rights reserved