2 research outputs found

    APROVEITAMENTO DO RESÍDUO DE CAMARÃO

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    O presente trabalho de revisão de literatura teve como objetivo fornecer informações sobre a importância do aproveitamento dos resíduos do beneficiamento do camarão. Foram abordados os componentes estruturais do camarão e suas características químicas, a evolução da carcinicultura e sua relação com o meio ambiente e o aproveitamento dos resíduos do beneficiamento. O estudo evidenciou o grande potencial nutricional que os resíduos do beneficiamento do camarão apresentam, sendo necessárias pesquisas com o objetivo de viabilizar o seu aproveitamento para a alimentação humana

    Prospecting in silico antibacterial activity of a peptide from trypsin inhibitor isolated from tamarind seed

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    AbstractBacterial infections have become a global concern, stimulating the growing demand for natural and biologically safe therapeutic agents with antibacterial action. This study was evaluated the genotoxicity of the trypsin inhibitor isolated from tamarind seeds (TTI) and the antibacterial effect of TTI theoric model, number 56, and conformation number 287 (TTIp 56/287) and derived peptides in silico. TTI (0.3 and 0.6 mg.mL−1) did not cause genotoxicity in cells (p > 0.05). In silico, a greater interaction of TTIp 56/287 with the Gram-positive membrane (GP) was observed, with an interaction potential energy (IPE) of −1094.97 kcal.mol−1. In the TTIp 56/287-GP interaction, the Arginine, Threonine (Thr), and Lysine residues presented lower IPE. In molecular dynamics (MD), Peptidotrychyme59 (TVSQTPIDIPIGLPVR) showed an IPE of −518.08 kcal.mol−1 with the membrane of GP bacteria, and the Thr and Arginine residues showed the greater IPE. The results highlight new perspectives on TTI and its derived peptides antibacterial activity
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