3 research outputs found
Autismo: Um s铆ndromo resultante da disfun莽茫o de um sistema cerebral espec铆fico?
The syndrome of childhood autism possibly
results from dysfunction in a system of bilateral
neural structures that includes the ring of mesolimbic
cortex located in the mesial frontal and
temporal lobes, the neostriatum, and the anterior
and medial nuclear groups of the thalamus.
Since part of these structures constitute the
target of dopaminergic mesencephalic neurons,
autism may be related to neuromediator imbalance
in those structures. The dysfunction
could be consequent to macroscopic or microscopic
changes in the target area or in structures
functionally influencing them, and result from
a variety of causes such as perinatal viral infection,
insult to the periventricular watershed
area, or genetically determined neurochemical
abnormalities