Influência do certifica minas café nas lavouras cafeeiras de Alfenas – Sul de Minas Gerais

The Brazilian coffee production is outstanding in the world, especially the specialty coffee produced in Minas Gerais. The domestic and especially the international market are increasingly demanding the consumption of agricultural products; so coffee certification becomes a form of quality assurance and sustainable production. This study aimed at verifying whether the Certifica Minas Café coffee certification is a valid management tool for producers and the gains obtained from the quality of certified coffee. A semi-structured questionnaire was used to carry out a research among coffee producers of the Alfenas regional office served by the office of EMATER-MG in Machado-MG. The analysis revealed that certification stimulates the producer to better manage his or her property, helps to increase the production of specialty coffee and increases profitability. Therefore it is a valid management tool for small and medium producers, once large producers usually have an operational management control in their properties. However it is important that EMATER-MG be aware that the more the certified producers share their experience in the certification process with uncertified farmers, the greater the number of producers interested to join the certification program, once person-to-person advertising is still a market strength.A cafeicultura brasileira está em destaque no mundo, principalmente o café especial produzido no estado de Minas Gerais. O mercado nacional e principalmente o internacional está cada vez mais exigente no consumo de produtos agrícolas; sendo assim, a certificação do café torna-se uma ferramenta de garantia da qualidade e produção sustentável. Este trabalho teve por objetivo analisar se a certificação “Certifica Minas Café” que constitui uma ferramenta de gestão é válida para o produtor, bem como analisar os ganhos em função da qualidade do café certificado. Desta forma, realizou-se uma pesquisa, por meio de questionário semiestruturado, com os produtores de café de Alfenas. Dentre os fatores analisados, verificou-se que a certificação beneficia o produtor a gerir melhor a sua propriedade, auxilia no aumento da produção de café especial e aumenta a lucratividade. Portanto, é uma ferramenta de gestão válida para o agricultor familiar e médio produtor, visto que os grandes produtores geralmente possuem um controle gerencial ativo em suas propriedades. Contudo é importante a atenção de que quanto mais o agricultor familiar certificado compartilhar sua experiência no processo de certificação com os outros produtores que ainda não estão certificados, maior será o número de produtores interessado em aderir ao programa de certificação, porque a propaganda de pessoa para pessoa ainda é um dos canais de marketing mais fortes do mercado

Efeito dos diferentes intervalos de recuperação na percepção subjetiva de homens e mulheres

O tempo de intervalo entre as séries no exercício físico é uma variável que vem sendo utilizada como um meio de controle da intensidade e densidade do treinamento. Assim, o objetivo do estudo foi verificar a Percepção Subjetiva Esforço (PSE) em intervalos de recuperação (IRs) de 1 e 3 minutos durante 3 séries consecutivas no aparelho Leg Press 45° até a falha concêntrica momentânea entre homens e mulheres, utilizando-se da escala de OMNI-RES. Fizeram parte do estudo 14 voluntários, sendo 7 homens (22 anos ±3,14; 78 ±11,42Kg; 1,74m ±0,05) e 7 mulheres (23 anos ±3,76; 56,4Kg ±6,88; 1,63m ±0,07), ambos fisicamente ativos. Os dados foram coletados em dias alternados e de forma aleatorizada, respeitando um intervalo de 48 horas para realização da coleta da PSE. Para comprovar a distribuição da amostra foi utilizado o teste de Shapiro Wilk. Para identificar as diferenças entre o número de repetições e a PSE entre os gêneros foi adotado o teste de Mann-Whitney. Os resultados mostraram que na comparação entre os gêneros nas variáveis PSE, número de repetições e a soma do número de repetições nos dois intervalos estudados, não foi possível identificar diferença significativa entre os gêneros. Houve uma diminuição no número de repetições nos dois IRs, porém, não houve diferença significativa na PSE entre as séries em ambos os intervalos. A utilização da mesma para controle de intensidade para homens e mulheres, ainda é questionável, necessitando de mais estudos acerca do tema

Sensitivity and Specificity of Soluble Triggering Receptor Expressed on Myeloid Cells-1, Midregional Proatrial Natriuretic Peptide and Midregional Proadrenomedullin for Distinguishing Etiology and to Assess Severity in Community-Acquired Pneumonia

This study aimed to evaluate the diagnostic accuracy of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1), midregional proatrial natriuretic peptide (MR-proANP) and midregional proadrenomedullin (MR-proADM) to distinguish bacterial from viral community-acquired pneumonia (CAP) and to identify severe cases in children hospitalized for radiologically confirmed CAP. Index test results were compared with those derived from routine diagnostic tests, i.e., white blood cell (WBC) counts, neutrophil percentages, and serum C-reactive protein (CRP) and procalcitonin (PCT) levels.This prospective, multicenter study was carried out in the most important children’s hospitals (n = 11) in Italy and 433 otherwise healthy children hospitalized for radiologically confirmed CAP were enrolled. Among cases for whom etiology could be determined, CAP was ascribed to bacteria in 235 (54.3%) children and to one or more viruses in 111 (25.6%) children. A total of 312 (72.2%) children had severe disease.CRP and PCT had the best performances for both bacterial and viral CAP identification. The cut-off values with the highest combined sensitivity and specificity for the identification of bacterial and viral infections using CRP were ≥7.98 mg/L and ≤7.5 mg/L, respectively. When PCT was considered, the cut-off values with the highest combined sensitivity and specificity were ≥0.188 ng/mL for bacterial CAP and ≤0.07 ng/mL for viral CAP. For the identification of severe cases, the best results were obtained with evaluations of PCT and MR-proANP. However, in both cases, the biomarker cut-off with the highest combined sensitivity and specificity (≥0.093 ng/mL for PCT and ≥33.8 pmol/L for proANP) had a relatively good sensitivity (higher than 70%) but a limited specificity (of approximately 55%).This study indicates that in children with CAP, sTREM-1, MR-proANP, and MR-proADM blood levels have poor abilities to differentiate bacterial from viral diseases or to identify severe cases, highlighting that PCT maintains the main role at this regard

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney

BACKGROUND: The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal anti-inflammatory drugs (NSAIDs) with differing selectivity profiles: robenacoxib (COX-2 selective) and ketoprofen (COX-1 selective). RESULTS: In this four period crossover study, we compared the effect of four treatments: placebo, robenacoxib once or twice daily and ketoprofen once daily concomitantly with furosemide in seven healthy cats. For each period, urine and blood samples were collected at baseline and within 48 h of treatment starting. Plasma renin activity (PRA), plasma and urinary aldosterone concentrations, glomerular filtration rate (GFR) and 24 h urinary volumes, electrolytes and eicosanoids (PGE(2), 6-keto-PGF1(α,) TxB(2)), renal injury biomarker excretions [N-acetyl-beta-D-glucosaminidase (NAG) and Gamma-Glutamyltransferase] were measured. Urine volume (24 h) and urinary sodium, chloride and calcium excretions increased from baseline with all treatments. Plasma creatinine increased with all treatments except placebo, whereas GFR was significantly decreased from baseline only with ketoprofen. PRA increased significantly with placebo and once daily robenacoxib and the increase was significantly higher with placebo compared to ketoprofen (10.5 ± 4.4 vs 4.9 ± 5.0 ng ml(−1) h(−1)). Urinary aldosterone excretion increased with all treatments but this increase was inhibited by 75 % with ketoprofen and 65 % with once daily robenacoxib compared to placebo. Urinary PGE(2) excretion decreased with all treatments and excretion was significantly lower with ketoprofen compared to placebo. Urinary TxB(2) excretion was significantly increased from baseline only with placebo. NAG increased from baseline with all treatments. Immunohistochemistry on post-mortem renal specimens, obtained from a different group of cats that died naturally of non-renal causes, suggested constitutive COX-1 and COX-2 co-localization in many renal structures including the macula densa (MD). CONCLUSIONS: These data suggest that both COX-1 and COX-2 could generate the signal from the MD to the renin secreting cells in cats exposed to furosemide. Co-localization of COX isoenzymes in MD cells supports the functional data reported here. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12917-015-0598-z) contains supplementary material, which is available to authorized users

Extrato bruto de bactéria Teredinibacter turnera, processo de obtenção do extrato bruto, composição farmacêutica contendo o mesmo e uso no tratamento de distúrbios e desordens proliferativas

ConcedidaA presente invenção se refere ao extrato bruto de bactéria Teredinibacter turnera atuante como agente antiproliferativo e antiviral, empregado em uma composição farmacêutica para o uso em tratamento de distúrbios e desordens proliferativas em mamíferos e infecções celulares e virais