27 research outputs found
A classmate in distress: schoolchildren as bystanders and their reasons for how they act
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hShroom1 links a membrane bound protein to the actin cytoskeleton.
No full texthShroom1 (hShrm1) is a member of the Apx/Shroom (Shrm) protein family and was identified from a yeast two-hybrid screen as a protein that interacts with the cytoplasmic domain of melanoma cell adhesion molecule (MCAM). The characteristic signature of the Shrm family is the presence of a unique domain, ASD2 (Apx/Shroom domain 2). mRNA analysis suggests that hShrm1 is expressed in brain, heart, skeletal muscle, colon, small intestine, kidney, placenta and lung tissue, as well a variety of melanoma and other cell lines. Co-immunoprecipitation and bioluminescence resonance energy transfer (BRET) experiments indicate that hShrm1 and MCAM interact in vivo and by immunofluorescence microscopy some co-localization of these proteins is observed. hShrm1 partly co-localises with beta-actin and is found in the Triton X-100 insoluble fraction of melanoma cell extracts. We propose that hShrm1 is involved in linking MCAM to the cytoskeleton
The effect of cultivar maturity on the resistance of potatoes to early blight caused byAlternaria solani
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The tectono‐sedimentary evolution of a supra‐detachment rift basin at a deep‐water magma‐poor rifted margin: the example of the Samedan Basin preserved in the Err nappe in SE Switzerland
No full textPLASMA CORTICOTROPHIN LEVELS DURING INSULIN-HYPOGLYCAEMIA : COMPARISON OF RADIOIMMUNOASSAY AND CYTOCHEMICAL BIOASSAY
No full textCaracterização etiológica, epidemiológica e clínico-patológica da meningoencefalite por herpesvírus bovino em bovinos no Estado de Goiás
No full textTopographical distribution of corticotropin-releasing factor type 2 receptor-like immunoreactivity in the rat dorsal raphe nucleus: co-localization with tryptophan hydroxylase
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