Tecnología educativa radiofónica en la frontera colombo-venezolana a mediados del siglo XX

Se establecen los orígenes y las diferencias entre la programación radial para la instrucción pública y la educación popular articulada a la estrategia radial nacional de Acción Cultural Popular —ACPO—, que se apoyaba en materiales didácticos multimediales, como locutores, tutores, libros, periódicos, manuales, etc., y fue emprendida desde Colombia hasta la frontera con Venezuela. Los análisis son descriptivos y se demuestra el interés estatal por la educación formal y virtual con apoyo de tecnologías remplazables y adaptables entre sí.This study establishes the origins of and differences between the radio programming for public education and radio programming for popular education articulated by the national radio strategy of Popular Cultural Action (Acción Cultural Popular —ACPO—). This strategy was based on multimedia teaching materials, such as speakers, tutors, books, newspapers, and manuals, and was implemented across Colombia to the Colombia-Venezuela border. The analyses are descriptive and demonstrate the state’s interest in formal and virtual education with support from replaceable and adaptable technologies

Metabolism of captopril carboxyl ester derivatives for percutaneous absorption

Original article can be found at: http://www.medicinescomplete.com/journals/jpp/current/ Copyright Pharmaceutical Press [Full text of this article is not available in the UHRA]To determine the metabolism of captopril n-carboxyl derivatives and how this may impact on their use as transdermal prodrugs. The pharmacological activity of the ester derivatives was also characterised in order to compare the angiotensin converting enzyme inhibitory potency of the derivatives compared with the parent drug, captopril.Peer reviewe

Moving beyond mindfulness: defining equanimity as an outcome measure in meditation and contemplative research

In light of a growing interest in contemplative practices such as meditation, the emerging field of contemplative science has been challenged to describe and objectively measure how these practices affect health and well-being. While "mindfulness" itself has been proposed as a measurable outcome of contemplative practices, this concept encompasses multiple components, some of which, as we review here, may be better characterized as equanimity. Equanimity can be defined as an even-minded mental state or dispositional tendency toward all experiences or objects, regardless of their origin or their affective valence (pleasant, unpleasant, or neutral). In this article, we propose that equanimity be used as an outcome measure in contemplative research. We first define and discuss the inter-relationship between mindfulness and equanimity from the perspectives of both classical Buddhism and modern psychology and present existing meditation techniques for cultivating equanimity. We then review psychological, physiological, and neuroimaging methods that have been used to assess equanimity either directly or indirectly. In conclusion, we propose that equanimity captures potentially the most important psychological element in the improvement of well-being, and therefore should be a focus in future research studies

Deexcitation Dynamics of Muonic Atoms Revealed by High-Precision Spectroscopy of Electronic K X rays

International audienceWe observed electronic K x rays emitted from muonic iron atoms using superconducting transition-edge sensor microcalorimeters. The energy resolution of 5.2 eV in FWHM allowed us to observe the asymmetric broad profile of the electronic characteristic Kα and Kβ x rays together with the hypersatellite Khα x rays around 6 keV. This signature reflects the time-dependent screening of the nuclear charge by the negative muon and the L-shell electrons, accompanied by electron side feeding. Assisted by a simulation, these data clearly reveal the electronic K- and L-shell hole production and their temporal evolution on the 10–20 fs scale during the muon cascade process

Measuring the electron neutrino mass with improved sensitivity: the HOLMES experiment

International audienceHOLMES is a new experiment aiming at directly measuring the neutrino mass with a sensitivity below 2 eV . HOLMES will perform a calorimetric measurement of the energy released in the decay of (163)Ho. The calorimetric measurement eliminates systematic uncertainties arising from the use of external beta sources, as in experiments with spectrometers. This measurement was proposed in 1982 by A. De Rujula and M. Lusignoli, but only recently the detector technological progress has allowed to design a sensitive experiment. HOLMES will deploy a 1000 pixels array of low temperature microcalorimeters with implanted (163)Ho nuclei. HOLMES, besides being an important step forward in the direct neutrino mass measurement with a calorimetric approach, will also establish the potential of this approach to extend the sensitivity down to 0.1 eV and lower. The detectors used for the HOLMES experiment will be Mo/Cu bilayers TESs (Transition Edge Sensors) on SiN(x) membrane with gold absorbers. Microwave multiplexed rf-SQUIDs are the best available technique to read out large array of such detectors. An extensive R&D activity is in progress in order to maximize the multiplexing factor while preserving the performances of the individual detectors. To embed the (163)Ho into the gold absorbers a custom mass separator ion implanter is being developed. The current activities are focused on the the single detector performances optimization and on the (163)Ho isotope production and embedding. A preliminary measurement of a sub-array of 4× 16 detectors is planned late in 2017. In this contribution we present the HOLMES project with its technical challenges, its status and perspectives