Late Eocene-Oligocene granulite facies garnet-sillimanite migmatites from the Mogok Metamorphic belt, Myanmar, and implications for timing of slip along the Sagaing Fault

MPS is grateful to the Oxford-Burma Aung San Suu Kyi trust for funding research and field visits to Mogok. U-Th-Pb geochronology was funded by UCSB and NSF grants EAR-1348003 and EAR-1551054 to BH.The Mogok Metamorphic Belt (MMB) in Myanmar is a polymetamorphic, mainly Paleogene granulite-uppermost amphibolite facies terrane consisting mainly of marbles and calc-silicates hosting spinel, ruby and sapphire. Jurassic charnockite-syenite intrusions, as well as Eocene-Miocene leucogranite intrusions are also present. Pelitic rocks are uncommon, and where present, have sillimanite, both as primary inclusions in garnet and as secondary Bt + Sil coronas around garnet. Core samples from the Kyi-Tauk-Pauk gold mine at Thabeikkiyin, north of Mandalay, are mostly Grt + Bt + Sill gneisses and migmatites with uncommon interbanded Opx + Grt + Bt gneisses. Pseudosection modelling suggests prograde garnet growth occurred by biotite-dehydration melting that reached peak P–T conditions of 870–970 °C and ~ 0.9 GPa, and was followed by garnet breakdown forming coarse retrograde Bt + Sil coronas. U[sbnd]Pb monazite data show an early high-grade granulite event at 43–32 Ma, and a later upper amphibolite sillimanite-grade event peaking at 23–20 Ma, with a change in monazite chemistry after c. 22 Ma that is consistent with fluid/(melt) interaction and garnet breakdown. Elevated Th/U ratios from ~35 to 22 Ma, and at ~18 Ma are compatible with melt influx at that time, timing that is similar to the age of the regional Kabaing leucogranite in the Mogok valley area. Our data show that peak granulite facies metamorphism along the Mogok Metamorphic belt was mainly Middle Eocene-Early Oligocene, with upper amphibolite facies metamorphism extending to earliest Miocene. The MMB is cut abruptly by the Sagaing fault, a large-scale dextral fault that extends from the Andaman Sea north to the East Himalayan syntaxis. Our new U[sbnd]Pb monazite data constrain the oldest age of initiation of the eastern branch of the cross-cutting Sagaing dextral strike-slip fault atPostprintPeer reviewe

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Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.

Effective public health measures against SARS-CoV-2 require granular knowledge of population-level immune responses. We developed a Tripartite Automated Blood Immunoassay (TRABI) to assess the IgG response against three SARS-CoV-2 proteins. We used TRABI for continuous seromonitoring of hospital patients and blood donors (n = 72'250) in the canton of Zurich from December 2019 to December 2020 (pre-vaccine period). We found that antibodies waned with a half-life of 75 days, whereas the cumulative incidence rose from 2.3% in June 2020 to 12.2% in mid-December 2020. A follow-up health survey indicated that about 10% of patients infected with wildtype SARS-CoV-2 sustained some symptoms at least twelve months post COVID-19. Crucially, we found no evidence of a difference in long-term complications between those whose infection was symptomatic and those with asymptomatic acute infection. The cohort of asymptomatic SARS-CoV-2-infected subjects represents a resource for the study of chronic and possibly unexpected sequelae

Rho GTPase function in flies: insights from a developmental and organismal perspective.

Morphogenesis is a key event in the development of a multicellular organism and is reliant on coordinated transcriptional and signal transduction events. To establish the segmented body plan that underlies much of metazoan development, individual cells and groups of cells must respond to exogenous signals with complex movements and shape changes. One class of proteins that plays a pivotal role in the interpretation of extracellular cues into cellular behavior is the Rho family of small GTPases. These molecular switches are essential components of a growing number of signaling pathways, many of which regulate actin cytoskeletal remodeling. Much of our understanding of Rho biology has come from work done in cell culture. More recently, the fruit fly Drosophila melanogaster has emerged as an excellent genetic system for the study of these proteins in a developmental and organismal context. Studies in flies have greatly enhanced our understanding of pathways involving Rho GTPases and their roles in development

All-sky search for long-duration gravitational wave transients with initial LIGO

We present the results of a search for long-duration gravitational wave transients in two sets of data collected by the LIGO Hanford and LIGO Livingston detectors between November 5, 2005 and September 30, 2007, and July 7, 2009 and October 20, 2010, with a total observational time of 283.0 days and 132.9 days, respectively. The search targets gravitational wave transients of duration 10-500 s in a frequency band of 40-1000 Hz, with minimal assumptions about the signal waveform, polarization, source direction, or time of occurrence. All candidate triggers were consistent with the expected background; as a result we set 90% confidence upper limits on the rate of long-duration gravitational wave transients for different types of gravitational wave signals. For signals from black hole accretion disk instabilities, we set upper limits on the source rate density between 3.4×10-5 and 9.4×10-4 Mpc-3 yr-1 at 90% confidence. These are the first results from an all-sky search for unmodeled long-duration transient gravitational waves. © 2016 American Physical Society

All-sky search for long-duration gravitational wave transients with initial LIGO

We present the results of a search for long-duration gravitational wave transients in two sets of data collected by the LIGO Hanford and LIGO Livingston detectors between November 5, 2005 and September 30, 2007, and July 7, 2009 and October 20, 2010, with a total observational time of 283.0 days and 132.9 days, respectively. The search targets gravitational wave transients of duration 10-500 s in a frequency band of 40-1000 Hz, with minimal assumptions about the signal waveform, polarization, source direction, or time of occurrence. All candidate triggers were consistent with the expected background; as a result we set 90% confidence upper limits on the rate of long-duration gravitational wave transients for different types of gravitational wave signals. For signals from black hole accretion disk instabilities, we set upper limits on the source rate density between 3.4×10-5 and 9.4×10-4 Mpc-3 yr-1 at 90% confidence. These are the first results from an all-sky search for unmodeled long-duration transient gravitational waves. © 2016 American Physical Society

Timing of syenite-charnockite magmatism and ruby- and sapphire metamorphism in the Mogok valley region, Myanmar

We thank the Oxford–Burma Aung San Suu Kyi trust for funding research and fieldwork visits to Myanmarfor MS,NG and LR. Geochronology was funded by UCSB and NSF grants EAR-1348003and EAR-1551054.The Mogok metamorphic belt (MMB) extends for over 1,000 km along central Burma from the Andaman Sea to the East Himalayan syntaxis and represents exhumed lower and middle crustal metamorphic rocks of the Sibumasu plate. In the Mogok valley region, the MMB consists of regional high‐grade marbles containing calcite + phlogopite + spinel + apatite ± diopside ± olivine and hosts world class ruby and sapphire gemstones. The coarse‐grained marbles have been intruded by orthopyroxene‐ and clinopyroxene‐bearing charnockite‐syenite sheet‐like intrusions that have skarns around the margins. Syenites range from hornblende‐ to quartz‐bearing and frequently show layering that could be a primary igneous texture or a later metamorphic overprint. Calc‐silicate skarns contain both rubies and blue sapphires with large biotites. Rubies occur in marbles with scapolite, phlogopite, graphite, occasional diopside, and blue apatite. Both marbles and syenites have been intruded by the Miocene Kabaing garnet‐muscovite‐biotite peraluminous leucogranite. New mapping and structural observations combined with U‐Th‐Pb zircon, monazite, and titanite geochronology from syenites, charnockites, leucogranites, meta‐rhyolite‐tuffs, and skarns have revealed a complex multiphase igneous and metamorphic history for the MMB. U‐Pb zircon ages of the charnockite‐syenites fall into three categories, Jurassic (170–168 Ma), latest Cretaceous to early Paleocene (~68‐63 Ma), and late Eocene–Oligocene (44–21 Ma). New ages from five samples suggest that metamorphism in the presence of garnet and melt occurred between ~45 and 24 Ma. U‐Pb titanite ages from the ruby marbles and meta‐skarns at Le Oo mine in the Mogok valley are 21 Ma, similar to titanite ages from an adjacent syenite (22 Ma). U‐Th‐Pb dating shows that all the metamorphic ages are Late Cretaceous–early Miocene and related to the India‐Sibumasu collision.Publisher PDFPeer reviewe