714 research outputs found
Kinetic resolution of alkyne-substituted quaternary oxindoles via copper catalysed azide-alkyne cycloadditions
Kinetic resolution of alkyne-substituted quaternary oxindoles via copper catalysed azide-alkyne cycloaddition
Asymmetric copper catalyzed azide-alkyne cycloadditions
Since its discovery independently by Sharpless and Meldal in 2002, the copper-catalyzed azideâalkyne cycloaddition (CuAAC) has become a ubiquitous molecular linking platform. Easy access to substituted 1,4-triazoles can be exploited to engender asymmetry to a myriad of potentially useful targets in high yields. Utilizing the CuAAC to form chiral triazolic products in a single step is an attractive and powerful approach for the synthetic chemist. The area of asymmetric CuAAC is still in its infancy compared to more established asymmetric metal-mediated transformations; however, this leads to exciting challenges that need to be overcome to usher in the next era in the story of the triazole and click chemistry in general. This review details the steps taken into asymmetric CuAAC and the exciting results achieved thus far. [Note that diagrams accompany this abstract in the published version and can be found at http://dx.doi.org/10.1021/acscatal.6b00996.
On the power counting of loop diagrams in general relativity
A class of loop diagrams in general relativity appears to have a behavior
which would upset the utility of the energy expansion for quantum effects. We
show through the study of specific diagrams that cancellations occur which
restore the expected behaviour of the energy expansion. By considering the
power counting in a physical gauge we show that the apparent bad behavior is a
gauge artifact, and that the quantum loops enter with a well behaved energy
expansion.Comment: 29 pages, uses axodraw and epsfig.tex, one small .eps file is
included. The full PostScript version is also available as
http://het.phast.umass.edu/students/kakukk/powercount_hepth.p
An NMR-based nanostructure switch for quantum logic
We propose a nanostructure switch based on nuclear magnetic resonance (NMR)
which offers reliable quantum gate operation, an essential ingredient for
building a quantum computer. The nuclear resonance is controlled by the magic
number transitions of a few-electron quantum dot in an external magnetic field.Comment: 4 pages, 2 separate PostScript figures. Minor changes included. One
reference adde
On B_s -> mu+ mu- and Cold Dark Matter Scattering in the MSSM with Non-Universal Higgs Masses
We show that present experimental constraints on B_s -> mu+ mu- decay and the
CDMS upper limit on the cold dark matter elastic scattering cross section
already have significant impact on the parameter space of the minimal
supersymmetric extension of the Standard Model (MSSM) with non-universal
supersymmetry-breaking scalar masses for the Higgs multiplets (NUHM). The
relaxation of scalar universality in the MSSM allows the possibility of a
relatively light mass M_A for the pseudoscalar Higgs boson. The present upper
limit on B_s -> mu+ mu- already excludes much of the scope for this possibility
in the NUHM, in contrast to the constrained MSSM with universal scalar masses
(CMSSM), where B_s -> mu+ mu- decay does not exclude any ranges of parameters
not already excluded by b -> s \gamma decay. Cold dark matter scattering is
also enhanced for small M_A, but the impact of present upper limit on B_s ->
mu+ mu- on the NUHM parameter space is in many cases greater than that of the
CDMS scattering limit, particularly at large tanb.Comment: 17 pages, 14 eps figure
Ulcerative Colitis Physician Team-Work in the Treatment
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68011/2/10.1177_000992286400300203.pd
Physical Optimization of Quantum Error Correction Circuits
Quantum error correcting codes have been developed to protect a quantum
computer from decoherence due to a noisy environment. In this paper, we present
two methods for optimizing the physical implementation of such error correction
schemes. First, we discuss an optimal quantum circuit implementation of the
smallest error-correcting code (the three bit code). Quantum circuits are
physically implemented by serial pulses, i.e. by switching on and off external
parameters in the Hamiltonian one after another. In contrast to this, we
introduce a new parallel switching method that allows faster gate operation by
switching all external parameters simultaneously. These two methods are applied
to electron spins in coupled quantum dots subject to a Heisenberg coupling
H=J(t) S_1*S_2 which can generate the universal quantum gate
`square-root-of-swap'. Using parallel pulses, the encoding for three-bit
quantum error correction in a Heisenberg system can be accelerated by a factor
of about two. We point out that parallel switching has potential applications
for arbitrary quantum computer architectures.Comment: 13 pages, 6 figure
Quantum-Hall Quantum-Bits
Bilayer quantum Hall systems can form collective states in which electrons
exhibit spontaneous interlayer phase coherence. We discuss the possibility of
using bilayer quantum dot many-electron states with this property to create
two-level systems that have potential advantages as quantum bits.Comment: 4 pages, 4 figures included, version to appear in Phys. Rev. B (Rapid
Communications
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