742 research outputs found

    Rare coding variants in RCN3 are associated with blood pressure

    Get PDF

    Observational evidence of the influence of Antarctic stratospheric ozone variability on middle atmosphere dynamics

    Get PDF
    Modeling results have suggested that the circulation of the stratosphere and mesosphere in spring is strongly affected by the perturbations in heating induced by the Antarctic ozone hole. Here using both mesospheric MF radar wind observations from Rothera Antarctica (67°S, 68°W) as well as stratospheric analysis data, we present observational evidence that the stratospheric and mesospheric wind strengths are highly anti-correlated, and show their largest variability in November. We find that these changes are related to the total amount of ozone loss that occurs during the Antarctic spring ozone hole and particularly with the ozone gradients that develop between 57.5°S and 77.5°S. The results show that with increasing ozone loss during spring, winter conditions in the stratosphere and mesosphere persist longer into the summer. These results are discussed in the light of observations of the onset and duration of the Antarctic polar mesospheric cloud seaso

    Effective action and interaction energy of coupled quantum dots

    Full text link
    We obtain the effective action of tunnel-coupled quantum dots, by modeling the system as a Luttinger liquid with multiple barriers. For a double dot system, we find that the resonance conditions for perfect conductance form a hexagon in the plane of the two gate voltages controlling the density of electrons in each dot. We also explicitly obtain the functional dependence of the interaction energy and peak-splitting on the gate voltage controlling tunneling between the dots and their charging energies. Our results are in good agreement with recent experimental results, from which we obtain the Luttinger interaction parameter K=0.74K=0.74.Comment: 5 pgs,latex,3 figs,revised version to be publshed in Phys.Rev.

    Spontaneous Chiral-Symmetry Breaking in Three-Dimensional QED with a Chern--Simons Term

    Full text link
    In three-dimensional QED with a Chern--Simons term we study the phase structure associated with chiral-symmetry breaking in the framework of the Schwinger--Dyson equation. We give detailed analyses on the analytical and numerical solutions for the Schwinger--Dyson equation of the fermion propagator, where the nonlocal gauge-fixing procedure is adopted to avoid wave-function renormalization for the fermion. In the absence of the Chern--Simons term, there exists a finite critical number of four-component fermion flavors, at which a continuous (infinite-order) chiral phase transition takes place and below which the chiral symmetry is spontaneously broken. In the presence of the Chern--Simons term, we find that the spontaneous chiral-symmetry-breaking transition continues to exist, but the type of phase transition turns into a discontinuous first-order transition. A simple stability argument is given based on the effective potential, whose stationary point gives the solution of the Schwinger-Dyson equation.Comment: 34 pages, revtex, with 9 postscriptfigures appended (uuencoded

    The genetics of obesity and the metabolic syndrome

    Get PDF
    In this review, we discuss the genetic architecture of obesity and the metabolic syndrome, highlighting recent advances in identifying genetic variants and loci responsible for a portion of the variation in components of the metabolic syndrome, namely, adiposity traits, serum HDL and triglycerides, blood pressure, and glycemic traits. We focus particularly on recent progress from large-scale genome-wide association studies (GWAS), by detailing their successes and how lessons learned can pave the way for future discovery. Results from recent GWAS coalesce with earlier work suggesting numerous interconnections between obesity and the metabolic syndrome, developed through several potentially pleiotropic effects. We detail recent work by way of a case study on the cadherin 13 gene and its relation with adiponectin in the HyperGEN and the Framingham Heart Studies, and its association with obesity and the metabolic syndrome. We provide also a gene network analysis of recent variants related to obesity and metabolic syndrome discovered through genome-wide association studies, and 4 gene networks based on searching the NCBI database

    Spin Susceptibility and Superexchange Interaction in the Antiferromagnet CuO

    Full text link
    Evidence for the quasi one-dimensional (1D) antiferromagnetism of CuO is presented in a framework of Heisenberg model. We have obtained an experimental absolute value of the paramagnetic spin susceptibility of CuO by subtracting the orbital susceptibility separately from the total susceptibility through the 63^{63}Cu NMR shift measurement, and compared directly with the theoretical predictions. The result is best described by a 1D S=1/2S=1/2 antiferromagnetic Heisenberg (AFH) model, supporting the speculation invoked by earlier authors. We also present a semi-quantitative reason why CuO, seemingly of 3D structure, is unexpectedly a quasi 1D antiferromagnet.Comment: 7 pages including 4 tables and 9 figure

    Electronic structure, phase stability and chemical bonding in Th2_2Al and Th2_2AlH4_4

    Full text link
    We present the results of theoretical investigation on the electronic structure, bonding nature and ground state properties of Th2_2Al and Th2_2AlH4_4 using generalized-gradient-corrected first-principles full-potential density-functional calculations. Th2_2AlH4_4 has been reported to violate the "2 \AA rule" of H-H separation in hydrides. From our total energy as well as force-minimization calculations, we found a shortest H-H separation of 1.95 {\AA} in accordance with recent high resolution powder neutron diffraction experiments. When the Th2_2Al matrix is hydrogenated, the volume expansion is highly anisotropic, which is quite opposite to other hydrides having the same crystal structure. The bonding nature of these materials are analyzed from the density of states, crystal-orbital Hamiltonian population and valence-charge-density analyses. Our calculation predicts different nature of bonding for the H atoms along aa and cc. The strongest bonding in Th2_2AlH4_4 is between Th and H along cc which form dumb-bell shaped H-Th-H subunits. Due to this strong covalent interaction there is very small amount of electrons present between H atoms along cc which makes repulsive interaction between the H atoms smaller and this is the precise reason why the 2 {\AA} rule is violated. The large difference in the interatomic distances between the interstitial region where one can accommodate H in the acac and abab planes along with the strong covalent interaction between Th and H are the main reasons for highly anisotropic volume expansion on hydrogenation of Th2_2Al.Comment: 14 pages, 9 figure
    • …
    corecore