Flight simulators. Part 1: Present situation and trends. Part 2: Implications for training

The present situation and developments in the technology of flight simulators based on digital computers are evaluated from the standpoint of training airline flight crews. Areas covered are minicomputers and their advantages in terms of cost, space and time savings, software data packets, motion simulation, visual simulation and instructor aids. The division of training time between aircraft and simulator training and the possible advantages from increased use of simulators are evaluated

Transpiration during life cycle in controlled wheat growth

A previously developed model of wheat growth, designed for convenient incorporation into system level models of advanced space life support systems is described. The model is applied to data from an experiment that grew wheat under controlled conditions and measured fresh biomass and cumulated transpiration as a function of time. The adequacy of modeling the transpiration as proportional to the inedible biomass and an age factor that varies during the life cycle are discussed

Mass balances for a biological life support system simulation model

Design decisions to aid the development of future space based biological life support systems (BLSS) can be made with simulation models. The biochemistry stoichiometry was developed for: (1) protein, carbohydrate, fat, fiber, and lignin production in the edible and inedible parts of plants; (2) food consumption and production of organic solids in urine, feces, and wash water by the humans; and (3) operation of the waste processor. Flux values for all components are derived for a steady state system with wheat as the sole food source. The large scale dynamics of a materially closed (BLSS) computer model is described in a companion paper. An extension of this methodology can explore multifood systems and more complex biochemical dynamics while maintaining whole system closure as a focus

The Evidence Behind the Treatment of Canine Idiopathic Epilepsy

Oral phenobarbital and imepitoin in particular, followed by potassium bromide and levetiracetam are likely to be effective for the treatment of canine idiopathic epilepsy. There is strong evidence supporting the use of oral phenobarbital and imepitoin as ‘first line’ medications. However, there remains a lack of evidence for targeted treatment for the various individual epileptic phenotypes and quite limited evidence on direct comparisons of the efficacy between various anti-epileptic drugs

The Evidence Behind the Diagnostic Investigation of Canine Idiopathic Epilepsy

<p><strong>Clinical bottom line</strong></p><p>There remains until recently an overall lack of clarity for the practical criteria for the diagnosis of canine idiopathic epilepsy. Signalment and an interictal neurological examination are vital for the diagnosis of idiopathic epilepsy. Despite the current insufficient evidence, the emerge of new diagnostic methods, such as cerebrospinal fluid and/or serum biomarkers, advanced functional neuroimaging techniques and electroencephalography, is likely to change the diagnostic approach in canine epilepsy in the near future.</p

The Scattered Disk as the source of the Jupiter Family comets

The short period Jupiter family comets (JFCs) are thought to originate in the Kuiper Belt; specifically, a dynamical subclass of the Kuiper Belt known as the `scattered disk' is argued to be the dominant source of JFCs. However, the best estimates from observational surveys indicate that this source may fall short by more than two orders of magnitude the estimates obtained from theoretical models of the dynamical evolution of Kuiper belt objects into JFCs. We re-examine the scattered disk as a source of the JFCs and make a rigorous estimate of the discrepancy. We find that the uncertainties in the dynamical models combined with a change in the size distribution function of the scattered disk at faint magnitudes (small sizes) beyond the current observational limit offer a possible but problematic resolution to the discrepancy. We discuss several other possibilities: that the present population of JFCs is a large fluctuation above their long term average, that larger scattered disk objects tidally break-up into multiple fragments during close planetary encounters as their orbits evolve from the trans-Neptune zone to near Jupiter, or that there are alternative source populations that contribute significantly to the JFCs. Well-characterized observational investigations of the Centaurs, objects that are transitioning between the trans-Neptune Kuiper belt region and the inner solar system, can test the predictions of the non-steady state and the tidal break-up hypotheses. The classical and resonant classes of the Kuiper belt are worth re-consideration as significant additional or alternate sources of the JFCs.Comment: 33 pages, 6 figures. Revised Content. To be published in The Astrophysical Journa

Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?

We sought to identify the association between clinical risk factors and the diagnosis of idiopathic epilepsy (IE) or structural epilepsy (SE) in cats, using statistical models to identify combinations of discrete parameters from the patient signalment, history and neurological examination findings that could suggest the most likely diagnosis. Data for 138 cats with recurrent seizures were reviewed, of which 110 were valid for inclusion. Seizure aetiology was classified as IE in 57% and SE in 43% of cats. Binomial logistic regression analyses demonstrated that pedigree status, older age at seizure onset (particularly >7 years old), abnormal neurological examinations, and ictal vocalisation were associated with a diagnosis of SE compared to IE, and that ictal salivation was more likely to be associated with a diagnosis of IE than SE. These findings support the importance of considering inter-ictal neurological deficits and seizure history in clinical reasoning