389 research outputs found
The Hubbard model on the honeycomb lattice: from static and dynamical mean-field theories to lattice quantum Monte Carlo simulations
We study the one-band Hubbard model on the honeycomb lattice using a
combination of quantum Monte Carlo (QMC) simulations and static as well as
dynamical mean-field theory (DMFT). This model is known to show a quantum phase
transition between a Dirac semi-metal and the antiferromagnetic insulator. The
aim of this article is to provide a detailed comparison between these
approaches by computing static properties, notably ground-state energy,
single-particle gap, double occupancy, and staggered magnetization, as well as
dynamical quantities such as the single-particle spectral function. At the
static mean-field level local moments cannot be generated without breaking the
SU(2) spin symmetry. The DMFT approximation accounts for temporal fluctuations,
thus captures both the evolution of the double occupancy and the resulting
local moment formation in the paramagnetic phase. As a consequence, the DMFT
approximation is found to be very accurate in the Dirac semi-metallic phase
where local moment formation is present and the spin correlation length small.
However, in the vicinity of the fermion quantum critical point the spin
correlation length diverges and the spontaneous SU(2) symmetry breaking leads
to low-lying Goldstone modes in the magnetically ordered phase. The impact of
these spin fluctuations on the single-particle spectral function --
\textit{waterfall} features and narrow spin-polaron bands -- is only visible in
the lattice QMC approach.Comment: 10 pages + appendix on the structure of the self energy; 5 figure
Fast algorithm for calculating two-photon absorption spectra
We report a numerical calculation of the two-photon absorption coefficient of
electrons in a binding potential using the real-time real-space higher-order
difference method. By introducing random vector averaging for the intermediate
state, the task of evaluating the two-dimensional time integral is reduced to
calculating two one-dimensional integrals. This allows the reduction of the
computation load down to the same order as that for the linear response
function. The relative advantage of the method compared to the straightforward
multi-dimensional time integration is greater for the calculation of non-linear
response functions of higher order at higher energy resolution.Comment: 4 pages, 2 figures. It will be published in Phys. Rev. E on 1, March,
199
Proteome-level display by 2-dimensional chromatography of extracellular matrix-dependent modulation of the phenotype of bladder cancer cells
BACKGROUND: The extracellular matrix can have a profound effect upon the phenotype of cancer cells. Previous work has shown that growth of bladder cancer cells on a matrix derived from normal basement membrane suppresses many malignant features that are displayed when the cells are grown on a matrix that has been modified by malignant tumors. This work was undertaken to investigate proteome-level changes as determined by a new commercially available proteome display involving 2-dimensional chromatography for bladder cancer cells grown on different extracellular matrix preparations that modulate the expression of the malignant phenotype. RESULTS: Depending on the matrix, between 1300 and 2000 distinct peaks were detected by two-dimensional chromatographic fractionation of 2.1 – 4.4 mg of total cellular protein. The fractions eluting from the reversed-phase fractionation were suitable for mass spectrometric identification following only lyophilization and trypsin digestion and achieved approximately 10-fold higher sensitivity than was obtained with gel-based separations. Abundant proteins that were unique to cells grown on one of the matrices were identified by mass spectrometry. Following concentration, peaks of 0.03 AU provided unambiguous identification of protein components when 10% of the sample was analyzed, whereas peaks of 0.05 AU was approximately the lower limit of detection when the entire sample was separated on a gel and in-gel digestion was used. Although some fractions were homogeneous, others were not, and up to 3 proteins per fraction were identified. Strong evidence for post-translational modification of the unique proteins was noted. All 13 of the unique proteins from cells grown on Matrigel were related to MYC pathway. CONCLUSION: The system provides a viable alternative to 2-dimensional gel electrophoresis for proteomic display of biological systems. The findings suggest the importance of MYC to the malignant phenotype of bladder cancer cells
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector
Elevations in circulating glucose and gut hormones during feeding promote pancreatic islet cell viability in part via the calcium- and cAMP-dependent activation of the transcription factor CREB. Here, we describe a signaling module that mediates the synergistic effects of these pathways on cellular gene expression by stimulating the dephosphorylation and nuclear entry of TORC2, a CREB coactivator. This module consists of the calcium-regulated phosphatase calcineurin and the Ser/Thr kinase SIK2, both of which associate with TORC2. Under resting conditions, TORC2 is sequestered in the cytoplasm via a phosphorylation-dependent interaction with 14-3-3 proteins. Triggering of the calcium and cAMP second messenger pathways by glucose and gut hormones disrupts TORC2:14-3-3 complexes via complementary effects on TORC2 dephosphorylation; calcium influx increases calcineurin activity, whereas cAMP inhibits SIK2 kinase activity. Our results illustrate how a phosphatase/kinase module connects two signaling pathways in response to nutrient and hormonal cues
Light emission from a scanning tunneling microscope: Fully retarded calculation
The light emission rate from a scanning tunneling microscope (STM) scanning a
noble metal surface is calculated taking retardation effects into account. As
in our previous, non-retarded theory [Johansson, Monreal, and Apell, Phys. Rev.
B 42, 9210 (1990)], the STM tip is modeled by a sphere, and the dielectric
properties of tip and sample are described by experimentally measured
dielectric functions. The calculations are based on exact diffraction theory
through the vector equivalent of the Kirchoff integral. The present results are
qualitatively similar to those of the non-retarded calculations. The light
emission spectra have pronounced resonance peaks due to the formation of a
tip-induced plasmon mode localized to the cavity between the tip and the
sample. At a quantitative level, the effects of retardation are rather small as
long as the sample material is Au or Cu, and the tip consists of W or Ir.
However, for Ag samples, in which the resistive losses are smaller, the
inclusion of retardation effects in the calculation leads to larger changes:
the resonance energy decreases by 0.2-0.3 eV, and the resonance broadens. These
changes improve the agreement with experiment. For a Ag sample and an Ir tip,
the quantum efficiency is 10 emitted photons in the visible
frequency range per tunneling electron. A study of the energy dissipation into
the tip and sample shows that in total about 1 % of the electrons undergo
inelastic processes while tunneling.Comment: 16 pages, 10 figures (1 ps, 9 tex, automatically included); To appear
in Phys. Rev. B (15 October 1998
Search for Supernova Relic Neutrinos at Super-Kamiokande
A search for the relic neutrinos from all past core-collapse supernovae was
conducted using 1496 days of data from the Super-Kamiokande detector. This
analysis looked for electron-type anti-neutrinos that had produced a positron
with an energy greater than 18 MeV. In the absence of a signal, 90% C.L. upper
limits on the total flux were set for several theoretical models; these limits
ranged from 20 to 130 nu_e bar cm^-2 s^-1. Additionally, an upper bound of 1.2
nu_e bar cm^-2 s^-1 was set for the supernova relic neutrino flux in the energy
region E_nu > 19.3 MeV.Comment: 4 pages, 2 figures. Submitted to Physical Review Letters. New version
includes corrections to Figure 1. Also, text has been shortened to conform
with the space limitations of PR
Solar 8B and hep Neutrino Measurements from 1258 Days of Super-Kamiokande Data
Solar neutrino measurements from 1258 days of data from the Super-Kamiokande
detector are presented. The measurements are based on recoil electrons in the
energy range 5.0-20.0MeV. The measured solar neutrino flux is 2.32 +-
0.03(stat.) +0.08-0.07(sys.)*10^6cm^{-2}s^{-1}, which is
45.1+-0.5(stat.)+1.6-1.4(sys.)% of that predicted by the BP2000 SSM. The day vs
night flux asymmetry is 0.033+-0.022(stat.)+0.013-0.012(sys.). The recoil
electron energy spectrum is consistent with no spectral distortion
(\chi^2/d.o.f. = 19.0/18). The seasonal variation of the flux is consistent
with that expected from the eccentricity of the Earth's orbit (\chi^2/d.o.f. =
3.7/7). For the hep neutrino flux, we set a 90% C.L. upper limit of 40
*10^3cm^{-2}s^{-1}, which is 4.3 times the BP2000 SSM prediction.Comment: 7 pages, 5 figures, submitted to PRL (part of this paper
Search for Dark Matter WIMPs using Upward Through-going Muons in Super-Kamiokande
We present the results of indirect searches for Weakly Interacting Massive
Particles (WIMPs) with 1679.6 live days of data from the Super-Kamiokande
detector using neutrino-induced upward through-going muons. The search is
performed by looking for an excess of high energy muon neutrinos from WIMP
annihilations in the Sun, the core of the Earth, and the Galactic Center, as
compared to the number expected from the atmospheric neutrino background. No
statistically significant excess was seen. We calculate flux limits in various
angular cones around each of the above celestial objects. We obtain
conservative model-independent upper limits on WIMP-nucleon cross-section as a
function of WIMP mass and compare these results with the corresponding results
from direct dark matter detection experiments.Comment: 10 pages, 14 figures, Submitted to Phys. Rev.
Evidence for an oscillatory signature in atmospheric neutrino oscillation
Muon neutrino disappearance probability as a function of neutrino flight
length L over neutrino energy E was studied. A dip in the L/E distribution was
observed in the data, as predicted from the sinusoidal flavor transition
probability of neutrino oscillation. The observed L/E distribution constrained
nu_mu nu_tau neutrino oscillation parameters; 1.9x10^-3 < Delta m^2 <
3.0x10^-3 eV^2 and \sin^2(2theta) > 0.90 at 90% confidence level.Comment: 5 pages, 5 figures, submitted to PR
Search for nucleon decay via modes favored by supersymmetric grand unification models in Super-Kamiokande-I
We report the results for nucleon decay searches via modes favored by
supersymmetric grand unified models in Super-Kamiokande. Using 1489 days of
full Super-Kamiokande-I data, we searched for , , and modes. We found no
evidence for nucleon decay in any of these modes. We set lower limits of
partial nucleon lifetime 2.3, 1.3,
1.3 and 1.0 years at 90% confidence level for , , and modes, respectively. These results give a strong constraint on
supersymmetric grand unification models.Comment: 14 pages, 13 figure
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