53 research outputs found
Simultaneous Determination of Simvastatin and Ezetimibe in Tablets by HPLC
Abstract: A reverse phase high performance liquid chromatographic method was developed for the simultaneous determination of simvastatin and ezetimibe in tablet dosage forms. The separation was effected on a C18 Supelcosil column (250 mm x 4.6 mm; 5µ) using a mobile phase consisting of 0.01 M ammonium acetate buffer and acetonitrile (35:65 v/v) at a flow rate of 1 mL/min. The detection was made at 240 nm. The retention times for ezetimibe and simvastatin were 5.9 and 8.5 min respectively. Calibration curves were linear over the ranges of 0.5-40 µg/mL for simvastatin and 2.5-50 µg/mL for ezetimibe. The proposed method was validated as per the ICH and USP guidelines. The method is accurate and precise and found to be suitable for the quantitative analysis of both the drugs individually and in combination in tablet dosage forms
Major and minor fisheries harbours of India. 8. Fisherries harbours along the coasts of North Andhra Pradesh, Orissa and West Bengal
The present account gives information about the three major and five minor fisheries harbours along the coasts of north Andhra Pradesh, Orissa and West Benga
Safety and efficiency of eptifibatide in primary angioplasty patients with renal insufficiency
Is there any analytical bias in determining the association between ABO Blood group and coronary artery disease
Efficiency of bivalirudin in improving coronary flow in obstructive coronary artery disease patients
Prevalence of obesity and its influencing factors among rural and urban school children in Prakasam District of Andhra Pradesh, South India
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