461 research outputs found
Are Revealed Intentions Possible?
This paper asks whether it is possible to design an Intentions Revealing Experiment – that is, an
experiment in which the early moves of the decision maker in a dynamic decision problem reveal
the intentions of that decision maker regarding later moves in the decision problem. If such a type
of experiment is possible, then it will enable economists to test whether individuals have plans and
implement them – a basic assumption of all economic theories of dynamic decision making.
Unfortunately the main finding of the paper is in the form of two Impossibility Theorems which
show that, unless one is prepared to make certain assumptions, such an Intentions Revealing
Experiment is impossible. However, the paper does have a positive side – it describes the type of
assumptions that one needs to make in order to make an Intentions Revealing Experiment possible.This paper asks whether it is possible to design an Intentions Revealing Experiment – that is, an
experiment in which the early moves of the decision maker in a dynamic decision problem reveal
the intentions of that decision maker regarding later moves in the decision problem. If such a type
of experiment is possible, then it will enable economists to test whether individuals have plans and
implement them – a basic assumption of all economic theories of dynamic decision making.
Unfortunately the main finding of the paper is in the form of two Impossibility Theorems which
show that, unless one is prepared to make certain assumptions, such an Intentions Revealing
Experiment is impossible. However, the paper does have a positive side – it describes the type of
assumptions that one needs to make in order to make an Intentions Revealing Experiment possible.Articles published in or submitted to a Journal with I
Inferring Social Preferences over Income Distributions through Axioms
Numerous prior experimental studies have attempted to elicit people’s preferences over income
distributions through appropriately incentivated questions asking subjects to choose between distributions.
Instead, we follow the theoretical literature and start with the principles underlying these preferences.
Such principles include, for example, the Rawlsian principle and the Lorenz principle. We implement
possibly the first incentivated experiment concentrating solely and directly on these underlying principles.
In essence, the experiment asks subjects to state their preferred principles, with the appropriate incentive
being provided by the experimenter using the stated axioms to choose a preferred distribution from a
randomly generated set, and this preferred distribution then being implemented on the participants in the
experiment. Thus one of the subjects becomes the Social Planner. (We have two treatments, one in which
the Social Planner is part of society and the second in which the Social Planner is outside society.) We solve
problems implied when the chosen set of principle is either mutually contradictory or incomplete (by allowing sequential choice). We observe that the implied social preferences are different from those inferred indirectly through choice over distributions as in the earlier experimental studies, and that elicited preferences are different between the two treatments, suggesting that the disinterested Social Planner is more Equality-preferring than the Social Planner with self-interest.Numerous prior experimental studies have attempted to elicit people’s preferences over income
distributions through appropriately incentivated questions asking subjects to choose between distributions.
Instead, we follow the theoretical literature and start with the principles underlying these preferences.
Such principles include, for example, the Rawlsian principle and the Lorenz principle. We implement
possibly the first incentivated experiment concentrating solely and directly on these underlying principles.
In essence, the experiment asks subjects to state their preferred principles, with the appropriate incentive
being provided by the experimenter using the stated axioms to choose a preferred distribution from a
randomly generated set, and this preferred distribution then being implemented on the participants in the
experiment. Thus one of the subjects becomes the Social Planner. (We have two treatments, one in which
the Social Planner is part of society and the second in which the Social Planner is outside society.) We solve
problems implied when the chosen set of principle is either mutually contradictory or incomplete (by allowing sequential choice). We observe that the implied social preferences are different from those inferred indirectly through choice over distributions as in the earlier experimental studies, and that elicited preferences are different between the two treatments, suggesting that the disinterested Social Planner is more Equality-preferring than the Social Planner with self-interest.Non-Refereed Working Papers / of national relevance onl
Corporate Image. Un secolo d'immagine coordinata dall'AEG alla NIke
La corporate image (o corporate identity) \ue8 tema di grande interesse e attualit\ue0. Cresce e si allarga, infatti, l\u2019esigenza delle aziende e delle istituzioni pubbliche di definire la propria identit\ue0 e di costruire una strategia per comunicarla, dal logo e dal lettering fino all\u2019articolazione di appositi eventi. Questo libro ne ricostruisce le origini e gli sviluppi teorici attraverso le principali fasi che hanno caratterizzato lo sviluppo della societ\ue0 industriale dagli inizi del Novecento a oggi. Approfondisce poi, con schede dettagliate, una serie di casi significativi di cui analizza le principali caratteristiche progettuali. Fino ai giorni nostri, in cui la mondializzazione e la rivoluzione informativo-informatica modificano la stessa concezione della grafica e sembrano delineare differenti ipotesi di lavoro sul terreno della comunicazione aziendale
On Choosing a Constitution (at least the part relating to the distribution of income)
A Constitution is a collection of principles or axioms determining how society should be organised, and a description of the ordering of the axioms in terms of their importance and of their invocation. We report on an experiment aimed at discovering preferred axioms relating to the distribution of income within society.A Constitution is a collection of principles or axioms determining how society should be organised, and a description of the ordering of the axioms in terms of their importance and of their invocation. We report on an experiment aimed at discovering preferred axioms relating to the distribution of income within society.Articles published in or submitted to a Journal with I
Architectural Challenges and Solutions for Collocated LWIP - A Network Layer Perspective
Achieving a tighter level of aggregation between
LTE and Wi-Fi networks at the radio access network (a.k.a.
LTE-Wi-Fi Aggregation or LWA) has become one of the most
prominent solutions in the era of 5G to boost network capacit
y
and improve end user's quality of experience. LWA offers
flexible resource scheduling decisions for steering user tr
affic
via LTE and Wi-Fi links. In this work, we propose a Collocated
LTE/WLAN Radio Level Integration architecture at IP layer
(C-LWIP), an enhancement over 3GPP non-collocated LWIP
architecture. We have evaluated C-LWIP performance in vari
ous
link aggregation strategies (LASs). A C-LWIP node (
i.e.
, the node
having collocated, aggregated LTE eNodeB and Wi-Fi access
point functionalities) is implemented in NS-3 which introd
uces a
traffic steering layer (
i.e.
, Link Aggregation Layer) for efficient
integration of LTE and Wi-Fi. Using extensive simulations,
we
verified the correctness of C-LWIP module in NS-3 and evaluat
ed
the aggregation benefits over standalone LTE and Wi-Fi netwo
rks
with respect to varying number of users and traffic types. We
found that split bearer performs equivalently to switched b
earer
for UDP flows and switched bearer outperforms split bearer in
the case of TCP flows. Also, we have enumerated the potential
challenges to be addressed for unleashing C-LWIP capabilit
ies.
Our findings also include WoD-Link Aggregation Strategy whi
ch
is shown to improve system throughput by 50% as compared to
Naive-LAS in a densely populated indoor stadium environmen
t
Assessing Measurable Residual Disease in Chronic Myeloid Leukemia. BCR-ABL1 IS in the Avant-Garde of Molecular Hematology
Chronic myelogenous leukemia (CML) is a malignancy of the myeloid cell lineage characterized by a recurrent chromosomal abnormality: the Philadelphia chromosome, which results from the reciprocal translocation of the chromosomes 9 and 22. The Philadelphia chromosome contains a fusion gene called BCR-ABL1. The BCR-ABL1 codes for an aberrantly functioning tyrosine kinase that drives the malignant proliferation of the founding clone. The advent of tyrosine kinase inhibitors (TKI) represents a landmark in the treatment of CML, that has led to tremendous improvement in the remission and survival rates. Since the introduction of imatinib, the first TKI, several other TKI have been approved that further broadened the arsenal against CML. Patients treated with TKIs require sensitive monitoring of BCR-ABL1 transcripts with quantitative real-time polymerase chain reaction (qRT-PCT), which has become an essential part of managing patients with CML. In this review, we discuss the importance of the BCR-ABL1 assay, and we highlight the growing importance of BCR-ABL1 dynamics. We also introduce a mathematical correction for the BCR-ABL1 assay that could help homogenizing the use of the ABL1 as a control gene. Finally, we discuss the growing body of evidence concerning treatment-free remission. Along with the continuous improvement in the therapeutic arsenal against CML, the molecular monitoring of CML represents the avant-garde in the struggle to make CML a curable disease
Versatile regularisation toolkit for iterative image reconstruction with proximal splitting algorithms
Ill-posed image recovery requires regularisation to ensure stability. The presented open-source regularisation toolkit consists of state-of-the-art variational algorithms which can be embedded in a plug-and-play fashion
into the general framework of proximal splitting methods. The packaged regularisers aim to satisfy various prior expectations of the investigated objects, e.g., their structural characteristics, smooth or non-smooth surface morphology.
The flexibility of the toolkit helps with the design of more advanced model-based iterative reconstruction methods
for different imaging modalities while operating with simpler building blocks. The toolkit is written for CPU and
GPU architectures and wrapped for Python/MATLAB. We demonstrate the functionality of the toolkit in application
to Positron Emission Tomography (PET) and X-ray synchrotron computed tomography (CT)
Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation
AbstractPancreatic cancers driven by KRAS mutations require additional mutations for tumor progression. The tumor suppressor FBXW7 is altered in pancreatic cancers, but its contribution to pancreatic tumorigenesis is unknown. To determine potential cooperation between Kras mutation and Fbxw7 inactivation in pancreatic tumorigenesis, we generated P48-Cre;LSL-KrasG12D;Fbxw7fl/fl (KFCfl/fl) compound mice. We found that KFCfl/fl mice displayed accelerated tumorigenesis: all mice succumbed to pancreatic ductal adenocarcinoma (PDA) by 40 days of age, with PDA onset occurring by 2 weeks of age. PDA in KFCfl/fl mice was preceded by earlier onset of acinar-to-ductal metaplasia (ADM) and pancreatic intraepithelial neoplasia (PanIN) lesions, and associated with chromosomal instability and the accumulation of Fbxw7 substrates Yes-associated protein (Yap), c-Myc, and Notch. Using KFCfl/fl and FBXW7-deficient human pancreatic cancer cells, we found that Yap silencing attenuated growth promotion by Fbxw7 deletion. Our data demonstrate that Fbxw7 is a potent suppressor of KrasG12D-induced pancreatic tumorigenesis due, at least in part, to negative regulation of Yap
Laser cleaning of gilded wood: a comparative study of colour variations induced by irradiation at different wavelengths
There is a growing interest by art conservators for laser cleaning of wood artworks, since traditional cleaning with chemical solvents can be a source of decay, due to the prolonged action of chemicals after the restoration. In this experiment we used excimer and Nd:YAGlasers, emitting radiation in the ultraviolet (248 nm), visible (532 nm) and near infrared (1064 nm), to investigate the effect of laser interaction on gilded wood samples at different wavelengths
Vibration issues in timber structures: A state-of-the-art review
The increasing use of timber structures worldwide has brought attention to the challenges posed by their lightweight nature, making them more prone to vibrations than more massive structures. Consequently, significant research efforts have been dedicated to understanding and mitigating vibrations in timber structures, while scientific committees strive to establish suitable design regulations. This study aims to classify and identify the main research themes related to timber structure vibrations and highlight future research needs and directions. A bibliometricbased selection process briefly introduces each research topic, presenting the latest findings and proposals for vibration design in timber structures. The paper emphasizes the key outcomes and significant contributions to understanding and addressing vibration issues in timber structures. These findings serve as valuable guidance for researchers, designers, and regulatory bodies involved in designing and assessing timber structures subjected to vibrations
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