Investigation of the use of a radioisotope for space environment simulation Final report

Beta emitting strontium 90 used as electron source for material testing in space environment simulation chambe

The art of HIV elimination: past and present science

Introduction: Remarkable strides have been made in controlling the HIV epidemic, although not enough to achieve epidemic control. More recently, interest in biomedical HIV control approaches has increased, but substantial challenges with the HIV cascade of care hinder successful implementation. We summarise all available HIV prevention methods and make recommendations on how to address current challenges. Discussion: In the early days of the epidemic, behavioural approaches to control the HIV dominated, and the few available evidence-based interventions demonstrated to reduce HIV transmission were applied independently from one another. More recently, it has become clear that combination prevention strategies targeted to high transmission geographies and people at most risk of infections are required to achieve epidemic control. Biomedical strategies such as male medical circumcision and antiretroviral therapy for treatment in HIV-positive individuals and as preexposure prophylaxis in HIV-negative individuals provide immense promise for the future of HIV control. In resourcerich settings, the threat of HIV treatment optimism resulting in increased sexual risk taking has been observed and there are concerns that as ART roll-out matures in resource-poor settings and the benefits of ART become clearly visible, behavioural disinhibition may also become a challenge in those settings. Unfortunately, an efficacious vaccine, a strategy which could potentially halt the HIV epidemic, remains elusive. Conclusion: Combination HIV prevention offers a logical approach to HIV control, although what and how the available options should be combined is contextual. Therefore, knowledge of the local or national drivers of HIV infection is paramount. Problems with the HIV care continuum remain of concern, hindering progress towards the UNAIDS target of 90-90-90 by 2020. Research is needed on combination interventions that address all the steps of the cascade as the steps are not independent of each other. Until these issues are addressed, HIV elimination may remain an unattainable goal

Multi-Person Pose Estimation with Local Joint-to-Person Associations

Despite of the recent success of neural networks for human pose estimation, current approaches are limited to pose estimation of a single person and cannot handle humans in groups or crowds. In this work, we propose a method that estimates the poses of multiple persons in an image in which a person can be occluded by another person or might be truncated. To this end, we consider multi-person pose estimation as a joint-to-person association problem. We construct a fully connected graph from a set of detected joint candidates in an image and resolve the joint-to-person association and outlier detection using integer linear programming. Since solving joint-to-person association jointly for all persons in an image is an NP-hard problem and even approximations are expensive, we solve the problem locally for each person. On the challenging MPII Human Pose Dataset for multiple persons, our approach achieves the accuracy of a state-of-the-art method, but it is 6,000 to 19,000 times faster.Comment: Accepted to European Conference on Computer Vision (ECCV) Workshops, Crowd Understanding, 201

Rapid testing may not improve uptake of HIV testing and same day results in a rural South African community: a cohort study of 12,000 women

<p>Background: Rapid testing of pregnant women aims to increase uptake of HIV testing and results and thus optimize care. We report on the acceptability of HIV counselling and testing, and uptake of results, before and after the introduction of rapid testing in this area.</p> <p>Methods and Principal Findings: HIV counsellors offered counselling and testing to women attending 8 antenatal clinics, prior to enrolment into a study examining infant feeding and postnatal HIV transmission. From August 2001 to April 2003, blood was sent for HIV ELISA testing in line with the Prevention of Mother-to-Child Transmission (PMTCT) programme in the district. From May 2003 to September 2004 women were offered a rapid HIV test as part of the PMTCT programme, but also continued to have ELISA testing for study purposes. Of 12,323 women counselled, 5,879 attended clinic prior to May 2003, and 6,444 after May 2003 when rapid testing was introduced; of whom 4,324 (74.6%) and 4,810 (74.6%) agreed to have an HIV test respectively. Of the 4,810 women who had a rapid HIV test, only 166 (3.4%) requested to receive their results on the same day as testing, the remainder opted to return for results at a later appointment. Women with secondary school education were less likely to agree to testing than those with no education (AOR 0.648, p<0.001), as were women aged 21–35 (AOR 0.762, p<0.001) and >35 years (AOR 0.756, p<0.01) compared to those <20 years.</p> <p>Conclusions: Contrary to other reports, few women who had rapid tests accepted their HIV results the same day. Finding strategies to increase the proportion of pregnant women knowing their HIV results is critical so that appropriate care can be given.</p&gt

Generalized survival in equilibrium step fluctuations

We investigate the dynamics of a generalized survival probability $S(t,R)$ defined with respect to an arbitrary reference level $R$ (rather than the average) in equilibrium step fluctuations. The exponential decay at large time scales of the generalized survival probability is numerically analyzed. $S(t,R)$ is shown to exhibit simple scaling behavior as a function of system-size $L$, sampling time $\delta t$, and the reference level $R$. The generalized survival time scale, $\tau_s(R)$, associated with $S(t,R)$ is shown to decay exponentially as a function of $R$.Comment: 4 pages, 2 figure

Bostonia. Volume 6

Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs

Does My Stigma Look Big in This? Considering the acceptability and desirability in the inclusive design of technology products

This paper examines the relationship between stigmatic effects of design of technology products for the older and disabled and contextualizes this within wider social themes such as the functional, social, medical and technology models of disability. Inclusive design approaches are identified as unbiased methods for designing for the wider population that may accommodate the needs and desires of people with impairments, therefore reducing ’aesthetic stigma’. Two case studies illustrate stigmatic and nonstigmatic designs

Nonlinear tunneling in two-dimensional lattices

We present thorough analysis of the nonlinear tunneling of Bose-Einstein condensates in static and accelerating two-dimensional lattices within the framework of the mean-field approximation. We deal with nonseparable lattices considering different initial atomic distributions in the highly symmetric states. For analytical description of the condensate before instabilities are developed, we derive several few-mode models, analyzing both essentially nonlinear and quasi-linear regimes of tunneling. By direct numerical simulations, we show that two-mode models provide accurate description of the tunneling when either initially two states are populated or tunneling occurs between two stable states. Otherwise a two-mode model may give only useful qualitative hints for understanding tunneling but does not reproduce many features of the phenomenon. This reflects crucial role of the instabilities developed due to two-body interactions resulting in non-negligible population of the higher bands. This effect becomes even more pronounced in the case of accelerating lattices. In the latter case we show that the direction of the acceleration is a relevant physical parameter which affects the tunneling by changing the atomic rates at different symmetric states and by changing the numbers of bands involved in the atomic transfer

Deep Eyes: Binocular Depth-from-Focus on Focal Stack Pairs

Human visual system relies on both binocular stereo cues and monocular focusness cues to gain effective 3D perception. In computer vision, the two problems are traditionally solved in separate tracks. In this paper, we present a unified learning-based technique that simultaneously uses both types of cues for depth inference. Specifically, we use a pair of focal stacks as input to emulate human perception. We first construct a comprehensive focal stack training dataset synthesized by depth-guided light field rendering. We then construct three individual networks: a Focus-Net to extract depth from a single focal stack, a EDoF-Net to obtain the extended depth of field (EDoF) image from the focal stack, and a Stereo-Net to conduct stereo matching. We show how to integrate them into a unified BDfF-Net to obtain high-quality depth maps. Comprehensive experiments show that our approach outperforms the state-of-the-art in both accuracy and speed and effectively emulates human vision systems

Are you a researcher as well as a medical illustrator?

When we list the areas of practice for medical illustrators we always include research, but how involved in research are we? The aim of this activity is to encourage your professional development not just as a medical illustrator but your involvement with research whether that is undertaking your own research, undertaking evidence based practice (1) , working as part of a research team, advising researchers on the value of medical illustration or supporting a student undertaking a research project for their degree or post-graduate qualification