2,465 research outputs found

    The U.S. fusion energy program

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    Differential scattering with charge transfer to the 2s state of hydrogen from H/+/-He and H/+/-Ar collisions

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    Differential scattering with charge transfer to hydrogen 2s state from proton collisions with helium and argo

    Repeatability of brown adipose tissue measurements on FDG PET/CT following a simple cooling procedure for BAT activation

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    Brown Adipose Tissue (BAT) is present in a significant number of adult humans and can be activated by exposure to cold. Measurement of active BAT presence, activity, and volume are desirable for determining the efficacy of potential treatments intended to activate BAT. The repeatability of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) measurements of BAT presence, activity, and volume under controlled conditions has not been extensively studied. Eleven female volunteers underwent double baseline FDG PET imaging performed following a simple, regional cold intervention intended to activate brown fat. The cold intervention involved the lightly-clothed participants intermittently placing their feet on a block of ice while sitting in a cooled room. A repeat study was performed under the same conditions within a target of two weeks. FDG scans were obtained and maximum standardized uptake value adjusted for lean body mass (SULmax), CT Hounsfield units (HU), BAT metabolic volume (BMV), and total BAT glycolysis (TBG) were determined according to the Brown Adipose Reporting Criteria in Imaging STudies (BARCIST) 1.0. A Lin's concordance correlation (CCC) of 0.80 was found for BMV between test and retest imaging. Intersession BAT SULmax was significantly correlated (r = 0.54; p < 0.05). The session #1 mean SULmax of 4.92 ± 4.49 g/mL was not significantly different from that of session #2 with a mean SULmax of 7.19 ± 7.34 g/mL (p = 0.16). BAT SULmax was highly correlated with BMV in test and retest studies (r ≥ 0.96, p < 0.001). Using a simplified ice-block cooling method, BAT was activated in the majority (9/11) of a group of young, lean female participants. Quantitative assessments of BAT SUL and BMV were not substantially different between test and retest imaging, but individual BMV could vary considerably. Intrasession BMV and SULmax were strongly correlated. The variability in estimates of BAT activity and volume on test-retest with FDG should inform sample size choice in studies quantifying BAT physiology and support the dynamic metabolic characteristics of this tissue. A more sophisticated cooling method potentially may reduce variations in test-retest BAT studies

    High Gene Flow Due to Pelagic Larval Dispersal Among South Pacific Archipelagos in Two Amphidromous Gastropods (Neritomorpha: Neritidae)

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    The freshwater stream fauna of tropical oceanic islands is dominated by amphidromous species, whose larvae are transported to the ocean and develop in the plankton before recruiting back to freshwater habitat as juveniles. Because stream habitat is relatively scarce and unstable on oceanic islands, this life history would seem to favor either the retention of larvae to their natal streams, or the ability to delay metamorphosis until new habitat is encountered. To distinguish between these hypotheses, we used population genetic methods to estimate larval dispersal among five South Pacific archipelagos in two amphidromous species of Neritid gastropod (Neritina canalis and Neripteron dilatatus). Sequence data from mitochondrial COI revealed that neither species is genetically structured throughout the Western Pacific, suggesting that their larvae have a pelagic larval duration of at least eight weeks, longer than many marine species. Additionally, the two species have recently colonized isolated Central Pacific archipelagos in three independent events. Since colonization, there has been little to no gene flow between the Western and Central Pacific archipelagos in Neritina canalis, and high levels of gene flow across the same region in Neripteron dilatatus. Both species show departures from neutrality and recent dates for colonization of the Central Pacific archipelagos consistent with frequent extinction and recolonization of stream populations in this area. Similar results from other amphidromous species suggest that unstable freshwater habitats promote long-distance dispersal capabilities

    Collisional Excitation Of N+ At 50 KeV

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    The excitation spectrum of N+ has been observed by examining the energy lost by a 50- keV N+ beam passing through a He target. The spectrum exhibits dramatic features with large cross sections. Determination of the approximate ratio of metastable to ground-state ions in the primary ion beam has permitted measurement of excitation cross sections from both ground-state and metastable N+ ions colliding with He target atoms. © 1972 The American Physical Society

    Geometric approach to nonvariational singular elliptic equations

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    In this work we develop a systematic geometric approach to study fully nonlinear elliptic equations with singular absorption terms as well as their related free boundary problems. The magnitude of the singularity is measured by a negative parameter (γ−1)(\gamma -1), for 0<γ<10 < \gamma < 1, which reflects on lack of smoothness for an existing solution along the singular interface between its positive and zero phases. We establish existence as well sharp regularity properties of solutions. We further prove that minimal solutions are non-degenerate and obtain fine geometric-measure properties of the free boundary F=∂{u>0}\mathfrak{F} = \partial \{u > 0 \}. In particular we show sharp Hausdorff estimates which imply local finiteness of the perimeter of the region {u>0}\{u > 0 \} and Hn−1\mathcal{H}^{n-1} a.e. weak differentiability property of F\mathfrak{F}.Comment: Paper from D. Araujo's Ph.D. thesis, distinguished at the 2013 Carlos Gutierrez prize for best thesis, Archive for Rational Mechanics and Analysis 201

    Contrasting Demographic History and Phylogeographic Patterns in Two Indo-Pacific Gastropods

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    Marine species with ranges that span the Indo-Australian Archipelago (IAA) exhibit a range of phylogeographic patterns, most of which are interpreted in the context of vicariance between Indian and Pacific Ocean populations during Pliocene and Pleistocene low sea level stands. However, patterns often vary among ecologically similar taxa, sometimes even within genera. This study compares phylogeographic patterns in two species of highly dispersive Neritid gastropod, Nerita albicilla and Nerita plicata, with nearly sympatric ranges that span the Indo-Pacific. Mitochondrial COI sequences from \u3e 1000 individuals from 97 sites reveal similar phylogenies in both species (two divergent clades differing by 3.2% and 2.3%, for N. albicilla and N. plicata respectively). However, despite ecological similarity and congeneric status, the two species exhibit phylogeographic discordance, with N. albicilla maintaining reciprocal monophyly of Indian and Pacific Ocean populations, while N. plicata is panmictic between oceans, but displays a genetic cline in the Central Pacific. Although this difference might be explained by qualitatively different demographic histories, parameter estimates from three coalescent models indicate that both species have high levels of gene flow between demes (2Ne m \u3e 75), and share a common history of population expansion that is likely associated with cyclical flooding of continental shelves and island lagoons following low sea level stands. Results indicate that ecologically similar co-distributed species may respond very differently to shared environmental processes, suggesting that relatively minor differences in traits such as pelagic larval duration or microhabitat association may profoundly impact phylogeographic structure

    Dynamical response of the "GGG" rotor to test the Equivalence Principle: theory, simulation and experiment. Part I: the normal modes

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    Recent theoretical work suggests that violation of the Equivalence Principle might be revealed in a measurement of the fractional differential acceleration η\eta between two test bodies -of different composition, falling in the gravitational field of a source mass- if the measurement is made to the level of η≃10−13\eta\simeq 10^{-13} or better. This being within the reach of ground based experiments, gives them a new impetus. However, while slowly rotating torsion balances in ground laboratories are close to reaching this level, only an experiment performed in low orbit around the Earth is likely to provide a much better accuracy. We report on the progress made with the "Galileo Galilei on the Ground" (GGG) experiment, which aims to compete with torsion balances using an instrument design also capable of being converted into a much higher sensitivity space test. In the present and following paper (Part I and Part II), we demonstrate that the dynamical response of the GGG differential accelerometer set into supercritical rotation -in particular its normal modes (Part I) and rejection of common mode effects (Part II)- can be predicted by means of a simple but effective model that embodies all the relevant physics. Analytical solutions are obtained under special limits, which provide the theoretical understanding. A simulation environment is set up, obtaining quantitative agreement with the available experimental data on the frequencies of the normal modes, and on the whirling behavior. This is a needed and reliable tool for controlling and separating perturbative effects from the expected signal, as well as for planning the optimization of the apparatus.Comment: Accepted for publication by "Review of Scientific Instruments" on Jan 16, 2006. 16 2-column pages, 9 figure

    Dynamics of a lattice Universe

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    We find a solution to Einstein field equations for a regular toroidal lattice of size L with equal masses M at the centre of each cell; this solution is exact at order M/L. Such a solution is convenient to study the dynamics of an assembly of galaxy-like objects. We find that the solution is expanding (or contracting) in exactly the same way as the solution of a Friedman-Lema\^itre-Robertson-Walker Universe with dust having the same average density as our model. This points towards the absence of backreaction in a Universe filled with an infinite number of objects, and this validates the fluid approximation, as far as dynamics is concerned, and at the level of approximation considered in this work.Comment: 14 pages. No figure. Accepted version for Classical and Quantum Gravit

    Expansion Dating: Calibrating Molecular Clocks in Marine Species from Expansions onto the Sunda Shelf Following the Last Glacial Maximum

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    The rate of change in DNA is an important parameter for understanding molecular evolution and hence for inferences drawn from studies of phylogeography and phylogenetics. Most rate calibrations for mitochondrial coding regions in marine species have been made from divergence dating for fossils and vicariant events older than 1-2 My and are typically 0.5-2% per lineage per million years. Recently, calibrations made with ancient DNA (aDNA) from younger dates have yielded faster rates, suggesting that estimates of the molecular rate of change depend on the time of calibration, decaying from the instantaneous mutation rate to the phylogenetic substitution rate. aDNA methods for recent calibrations are not available for most marine taxa so instead we use radiometric dates for sea-level rise onto the Sunda Shelf following the Last Glacial Maximum (starting similar to 18,000 years ago), which led to massive population expansions for marine species. Instead of divergence dating, we use a two-epoch coalescent model of logistic population growth preceded by a constant population size to infer a time in mutational units for the beginning of these expansion events. This model compares favorably to simpler coalescent models of constant population size, and exponential or logistic growth, and is far more precise than estimates from the mismatch distribution. Mean rates estimated with this method for mitochondrial coding genes in three invertebrate species are elevated in comparison to older calibration points (2.3-6.6% per lineage per million years), lending additional support to the hypothesis of calibration time dependency for molecular rates
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